(Q37575417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326426%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats (English)

1 reference

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2 March 2020

0 references

1 reference

1

1 reference

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2 March 2020

E Matthew Morris

3

1 reference

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2 March 2020

John Thyfault

11

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2 March 2020

R Scott Rector

12

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2 March 2020

2

Justin A Fletcher

1 reference

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2 March 2020

4

Grace M Meers

1 reference

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2 March 2020

8

Frank W Booth

1 reference

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2 March 2020

10

Jamal A Ibdah

1 reference

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2 March 2020

5

Monica L Kearney

1 reference

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2 March 2020

6

Jacqueline M Crissey

1 reference

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2 March 2020

author name string

M Harold Laughlin

7

1 reference

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2 March 2020

James R Sowers

9

1 reference

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2 March 2020

publication date

10 December 2013

1 reference

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American Journal of Physiology - Endocrinology and Metabolism

2 March 2020

published in

1 reference

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2 March 2020

volume

306

1 reference

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2 March 2020

issue

3

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2 March 2020

page(s)

E300-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326426%20AND%20SRC:MED&resulttype=core&format=json

Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults

2 March 2020

cites work

1 reference

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Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats

23 August 2017

1 reference

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Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats

23 August 2017

1 reference

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PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion.

23 August 2017

1 reference

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Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial.

23 August 2017

1 reference

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Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease

23 August 2017

1 reference

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The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

23 August 2017

1 reference

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Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease.

23 August 2017

1 reference

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Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Mice lacking TR4 nuclear receptor develop mitochondrial myopathy with deficiency in complex I.

23 August 2017

1 reference

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Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

23 August 2017

1 reference

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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Effects of metformin and weight loss on serum alanine aminotransferase activity in the diabetes prevention program

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Nonalcoholic hepatic steatosis in Zucker diabetic rats: spontaneous evolution and effects of metformin and fenofibrate

23 August 2017

1 reference

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Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Weight regain is related to decreases in physical activity during weight loss

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Effect of exercise on 24-month weight loss maintenance in overweight women

23 August 2017

1 reference

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Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function

23 August 2017

1 reference

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Non-alcoholic fatty liver disease and the metabolic syndrome: an update

23 August 2017

1 reference

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Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Hyperphagia and obesity in OLETF rats lacking CCK-1 receptors

23 August 2017

1 reference

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Hyperphagia and obesity of OLETF rats lacking CCK1 receptors: developmental aspects

23 August 2017

1 reference

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Nonalcoholic fatty liver disease: from steatosis to cirrhosis

23 August 2017

1 reference

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Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

23 August 2017

1 reference

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Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

23 August 2017

1 reference

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Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

A mathematical model for the determination of total area under glucose tolerance and other metabolic curves

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Exercise and Omega-3 Polyunsaturated Fatty Acid Supplementation for the Treatment of Hepatic Steatosis in Hyperphagic OLETF Rats

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Does physical inactivity cause nonalcoholic fatty liver disease?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Metformin reverses fatty liver disease in obese, leptin-deficient mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Effect of 6-month nutritional intervention on non-alcoholic fatty liver disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Comparison of the effects of pioglitazone and metformin on hepatic and extra-hepatic insulin action in people with type 2 diabetes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Metformin in non-alcoholic steatohepatitis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920010

Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease

1 September 2018

1 reference

12 December 2020

Prevalence of and risk factors for hepatic steatosis in Northern Italy

1 reference

12 December 2020

Loss of TR4 Orphan Nuclear Receptor Reduces Phosphoenolpyruvate Carboxykinase Mediated Gluconeogenesis

1 reference

12 December 2020

Metabolic differentiation of distinct muscle types at the level of enzymatic organization

1 reference

12 December 2020

Metformin decreases blood pressure and obesity in OLETF rats via improvement of insulin resistance

1 reference

12 December 2020

Metformin treatment enhances insulin-stimulated glucose transport in skeletal muscle of Sprague-Dawley rats

1 reference

12 December 2020

10.1152/AJPENDO.00427.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326426%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326426%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24326426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326426%20AND%20SRC:MED&resulttype=core&format=json