(Q37582435)

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Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

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Europe PubMed Central

PMC publication ID

21 August 2017

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

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Ian P Salt

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Benoit Viollet

7

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Erik A Richter

6

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author name string

Sarah J Mancini

1

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Europe PubMed Central

PMC publication ID

21 August 2017

Anna D White

2

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Europe PubMed Central

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21 August 2017

Silvia Bijland

3

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Europe PubMed Central

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21 August 2017

Claire Rutherford

4

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Europe PubMed Central

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21 August 2017

Delyth Graham

5

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Europe PubMed Central

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21 August 2017

Rhian M Touyz

8

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Europe PubMed Central

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21 August 2017

Timothy M Palmer

9

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Europe PubMed Central

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21 August 2017

publication date

10 November 2016

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Europe PubMed Central

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21 August 2017

Molecular and Cellular Endocrinology

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Europe PubMed Central

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21 August 2017

440

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Europe PubMed Central

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21 August 2017

44-56

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Europe PubMed Central

PMC publication ID

21 August 2017

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.

1 reference

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AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia.

1 reference

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1 reference

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23 August 2017

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.

1 reference

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23 August 2017

AMPK activation: a therapeutic target for type 2 diabetes?

1 reference

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The TLR and IL-1 signalling network at a glance

1 reference

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IL-6 in diabetes and cardiovascular complications.

1 reference

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Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue

1 reference

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AMP-activated protein kinase restricts IFN-γ signaling.

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Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

1 reference

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Nitric oxide-induced activation of the AMP-activated protein kinase α2 subunit attenuates IκB kinase activity and inflammatory responses in endothelial cells

1 reference

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Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans

1 reference

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23 August 2017

The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.

1 reference

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23 August 2017

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

1 reference

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AMPK inhibition in health and disease

1 reference

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23 August 2017

Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1

1 reference

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AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes

1 reference

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Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo

1 reference

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23 August 2017

Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

1 reference

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Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

1 reference

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The selectivity of protein kinase inhibitors: a further update

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

1 reference

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23 August 2017

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

1 reference

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Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

1 reference

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23 August 2017

Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes.

1 reference

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6 September 2017

Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes.

1 reference

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Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation.

1 reference

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Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.

1 reference

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AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300.

1 reference

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Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK.

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AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

1 reference

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AMPK-independent down-regulation of cFLIP and sensitization to TRAIL-induced apoptosis by AMPK activators

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14 September 2017

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase

1 reference

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A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism

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1 reference

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The total phenolic fraction of Anemarrhena asphodeloides inhibits inflammation and reduces insulin resistance in adipocytes via regulation of AMP-kinase activity

1 reference

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Induction of mitochondrial uncoupling enhances VEGF₁₂₀ but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways

1 reference

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25 June 2018

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5228585

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Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling.

1 reference

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PCR array and protein array studies demonstrate that IL-1β (interleukin-1β) stimulates the expression and secretion of multiple cytokines and chemokines in human adipocytes.

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Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase.

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Berberine suppresses proinflammatory responses through AMPK activation in macrophages

1 reference

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Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

1 reference

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Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase

1 reference

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1 September 2018

JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5228585

1 September 2018

AICAR stimulates adiponectin and inhibits cytokines in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5228585

1 September 2018

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5228585

1 September 2018

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27840174

12 December 2020

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10.1016/J.MCE.2016.11.010

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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