(Q37602062)

21 August 2017

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title

Bisubstrate inhibitors of protein kinases: from principle to practical applications (English)

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21 August 2017

1

Darja Lavogina

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Erki Enkvist

series ordinal

2

object named as

Erki Enkvist

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21 August 2017

Darja Lavogina

1

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21 August 2017

Asko Uri

series ordinal

3

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21 August 2017

publication date

1 January 2010

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21 August 2017

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21 August 2017

volume

5

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21 August 2017

issue

1

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21 August 2017

page(s)

23-34

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The design of drug candidate molecules as selective inhibitors of therapeutically relevant protein kinases

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Protein kinase inhibitors: insights into drug design from structure.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Extracellular activity of cyclic AMP-dependent protein kinase as a biomarker for human cancer detection: distribution characteristics in a normal population and cancer patients.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Features of selective kinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Designing bisubstrate analog inhibitors for protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Non-ATP-competitive kinase inhibitors - enhancing selectivity through new inhibition strategies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Peptide inhibitors of protein kinases-discovery, characterisation and use

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Modifications of the GSK3beta substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

On the attribution and additivity of binding energies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP- and protein-competitive ligands of cAMP-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Bisubstrate inhibition: Theory and application to N-acetyltransferases.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Protein kinase inhibitors: the tyrosine-specific protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella enterica Aminoglycoside 6‘- N -Acetyltransferase † , ‡

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Design of potent protein kinase inhibitors using the bisubstrate approach

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

PKA: a portrait of protein kinase dynamics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Crystallography for protein kinase drug design: PKA and SRC case studies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Mechanism-based design of a protein kinase inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

A Src-like inactive conformation in the abl tyrosine kinase domain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Protein tyrosine kinase-substrate interactions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Enzymatic transition states and transition state analog design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Fragment-based drug design: how big is too big?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Identification of inhibitors of protein kinase B using fragment-based lead discovery

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Allosteric cooperativity in protein kinase A.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Design, synthesis, and characterization of an ATP-peptide conjugate inhibitor of protein kinase A.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

ATP-conjugated peptide inhibitors for calmodulin-dependent protein kinase II

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Functional interrogation of the kinome using nucleotide acyl phosphates

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Kinase-catalyzed biotinylation for phosphoprotein detection

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Sulfonylbenzoyl-nitrostyrenes: potential bisubstrate type inhibitors of the EGF-receptor tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Synthesis and Evaluation of 3-Phenylpyrazolo[3,4-d]pyrimidine-Peptide Conjugates as Src Kinase Inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Design of new inhibitors for cdc2 kinase based on a multiple pseudosubstrate structure

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Increasing the kinase specificity of k252a by protein surface recognition.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Stepwise combinatorial evolution of Akt bisubstrate inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

A chemical genetic method for generating bivalent inhibitors of protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Adenosine-5'-carboxylic acid peptidyl derivatives as inhibitors of protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Identification of the ability of highly charged nanomolar inhibitors of protein kinases to cross plasma membranes and carry a protein into cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Liquid-phase synthesis of a pegylated adenosine-oligoarginine conjugate, cell-permeable inhibitor of cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Carbocyclic 3'-deoxyadenosine-based highly potent bisubstrate-analog inhibitor of basophilic protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: molecular yardsticks for analyzing catalytic mechanism and inhibitor design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Probing the catalytic mechanism of the insulin receptor kinase with a tetrafluorotyrosine-containing peptide substrate

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Development of photo-crosslinking reagents for protein kinase-substrate interactions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

ATP-phosphopeptide conjugates as inhibitors of Src tyrosine kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Analysis of protein kinase autophosphorylation using expressed protein ligation and computational modeling

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Bi-substrate analogue ligands for affinity chromatography of protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

https://api.crossref.org/works/10.1002%2FCMDC.200900252

1 reference

7 January 2021

Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900252

7 January 2021

Identifiers

DOI

10.1002/CMDC.200900252

1 reference

21 August 2017

1 reference