(Q37604379)

21 August 2017

1 reference

title

Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissues (English)

1 reference

21 August 2017

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Päivi Myllynen

1

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21 August 2017

Elina Immonen

series ordinal

2

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21 August 2017

Maria Kummu

series ordinal

3

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21 August 2017

Kirsi Vähäkangas

series ordinal

4

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21 August 2017

language of work or name

English

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publication date

1 December 2009

1 reference

Expert Opinion on Drug Metabolism & Toxicology

21 August 2017

published in

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21 August 2017

volume

5

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21 August 2017

issue

12

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21 August 2017

page(s)

1483-1499

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The fate and effects of xenobiotics in human placenta

21 August 2017

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21 January 2018

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Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds.

21 January 2018

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Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption

21 January 2018

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UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

21 January 2018

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The ontogeny of drug metabolism enzymes and implications for adverse drug events

21 January 2018

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ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS

21 January 2018

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Cytochrome P450IA expression in adult and fetal human liver

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

The expression and regulation of drug metabolism in human placenta

21 January 2018

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Human placenta: a human organ for developmental toxicology research and biomonitoring

21 January 2018

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Delayed ontogenesis of CYP1A2 in the human liver

21 January 2018

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Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy

21 January 2018

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Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta

21 January 2018

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The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line

21 January 2018

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Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

Developmental expression of human hepatic CYP2C9 and CYP2C19.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in man

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

Expression of CYP2D6 in developing human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Fetal hepatic drug elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

Human Hepatic CYP2E1 Expression during Development

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304049

Expression of CYP2E1 during embryogenesis and fetogenesis in human cephalic tissues: implications for the fetal alcohol syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Biochemical characterization and tissue distribution of human SULT2B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The contribution of fetal metabolism to the disposition of morphine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Fetal morphine metabolism and clearance are constant during late gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The human glutathione S-transferases: developmental aspects of the GST1, GST2, and GST3 loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression and function of efflux drug transporters in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Drug resistance in brain diseases and the role of drug efflux transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Mechanism of multidrug recognition by MDR1/ABCB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The multidrug-resistance P-glycoprotein (Pgp, MDR1) is an early marker of blood-brain barrier development in the microvessels of the developing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Fetal blood-brain barrier P-glycoprotein contributes to brain protection during human development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Functional role of P-glycoprotein in the human blood-placental barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Influence of P-glycoprotein on the transplacental passage of cyclosporine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression of the multidrug resistance P-glycoprotein, (ABCB1 glycoprotein) in the human placenta decreases with advancing gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Transfer of methadone across the dually perfused preterm human placental lobule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Distribution of saquinavir, methadone, and buprenorphine in maternal brain, placenta, and fetus during two different gestational stages of pregnancy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The impact of cocaine and heroin on the placental transfer of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Developmental expression of canalicular transporter genes in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The tissue distribution of murine Abcc6 (Mrp6) during embryogenesis indicates that the presence of Abcc6 in elastic tissues is not required for elastic fiber assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Clinical trial: modulation of human placental multidrug resistance proteins in cholestasis of pregnancy by ursodeoxycholic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Basal Membrane Localization of MRP1 in Human Placental Trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Mutations in ABCC6 cause pseudoxanthoma elasticum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

MRP6 (ABCC6) detection in normal human tissues and tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Role of the multidrug transporter proteins ABCB1 and ABCC2 in the diaplacental transport of talinolol in the term human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

21 January 2018

ABCG2: a perspective.

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression level of ABCG2 in the placenta decreases from the mid stage to the end of gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

BCRP/ABCG2 in the placenta: expression, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The developmental role of serotonin: news from mouse molecular genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Serotonin and its antidepressant-sensitive transport in mouse cumulus-oocyte complexes and early embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Ubiquitous embryonic expression of the norepinephrine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Cocaine up-regulates norepinephrine transporter binding in the rat placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Functional analysis of organic cation transporter 3 expressed in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Norepinephrine transporter (NET), serotonin transporter (SERT), vesicular monoamine transporter (VMAT2) and organic cation transporters (OCT1, 2 and EMT) in human placenta from pre-eclamptic and normotensive pregnancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Discovery of the ergothioneine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Gender-specific and developmental influences on the expression of rat organic anion transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Characterization and identification of steroid sulfate transporters of human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Differential expression of bile salt and organic anion transporters in developing rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Semi quantitative expression analysis of MDR3, FIC1, BSEP, OATP-A, OATP-C,OATP-D, OATP-E and NTCP gene transcripts in 1st and 3rd trimester human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

The role of the human placenta in embryonic nutrition. Impact of environmental and social factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Epigenetics in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Stability and flexibility of epigenetic gene regulation in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Ontogenic expression of hepatic Ahr mRNA is associated with histone H3K4 di-methylation during mouse liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Antiepileptic medication during pregnancy: does fetal genotype affect outcome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Effect of endotoxin on the expression of placental drug transporters and glyburide disposition in pregnant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Identification of definitive and fetal zone markers in the human fetal adrenal gland reveals putative developmental genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Characterization of ABC transporter ABCB1 expressed in human neural stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Genes encoding bile acid, phospholipid and anion transporters are expressed in a human fetal cardiomyocyte culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Therapeutic and adverse actions of serotonin transporter substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Substrate binding stoichiometry and kinetics of the norepinephrine transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304049

10.1517/17425250903304049

21 January 2018

Identifiers

DOI

1 reference

release_zhjepum3dfhs7dw6f7hozupnlm

21 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zhjepum3dfhs7dw6f7hozupnlm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference