(Q37604385)

21 August 2017

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title

Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines (English)

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21 August 2017

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Olivier Fardel

1

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21 August 2017

Marc Le Vée

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

1 December 2009

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Expert Opinion on Drug Metabolism & Toxicology

21 August 2017

published in

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21 August 2017

volume

5

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21 August 2017

issue

12

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21 August 2017

page(s)

1469-1481

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Altered theophylline pharmacokinetics during acute respiratory viral illness

21 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Drug uptake systems in liver and kidney

21 January 2018

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Bile acid transporters: structure, function, regulation and pathophysiological implications

21 January 2018

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Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

21 January 2018

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21 January 2018

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Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

21 January 2018

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A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

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The P-glycoprotein multidrug transporter

21 January 2018

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The ATP-binding cassette transporters and their implication in drug disposition: a special look at the heart

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cytokines Alter the Expression and Activity of the Multidrug Resistance Transporters in Human Hepatoma Cell Lines; Analysis Using RT‐PCR and cDNA Microarrays

21 January 2018

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Production of serum amyloid A and C-reactive protein by HepG2 cells stimulated with combinations of cytokines or monocyte conditioned media: the effects of prednisolone

21 January 2018

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Induction of ABCC3 (MRP3) by pregnane X receptor activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

21 January 2018

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Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

21 January 2018

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Methods to evaluate biliary excretion of drugs in humans: an updated review

21 January 2018

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P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

P-glycoprotein expression in human, mouse, hamster and rat hepatocytes in primary culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Decreased expression of an ATP-binding cassette transporter, MRP2, in human livers with hepatitis C virus infection

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Interleukin-1beta represses MRP2 gene expression through inactivation of interferon regulatory factor 3 in HepG2 cells

21 January 2018

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A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene

21 January 2018

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Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

21 January 2018

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Human hepatocytes: isolation, cryopreservation and applications in drug development

21 January 2018

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In vitro-in vivo correlation of hepatobiliary drug clearance in humans.

21 January 2018

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Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

21 January 2018

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Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Inflammation and interleukin-6 mediate reductions in the hepatic expression and transcription of the mdr1a and mdr1b Genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Inflammatory mechanisms in the regulation of insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

The effects of diabetes mellitus on pharmacokinetics and pharmacodynamics in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Hepatocyte nuclear factor (HNF) 1 and HNF4 mediate hepatic multidrug resistance protein 2 up-regulation during hepatitis C virus gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250903304056

Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

An update on metabolism studies using human hepatocytes in primary culture

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425250903304056

10.1517/17425250903304056

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

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