(Q37612417)

English

Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer

scientific article published on 18 January 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

dichloroacetate

0 references

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Heather R Christofk

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Edward B Garon

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Wylie Hosmer

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Carolyn D Britten

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Agnes Bahng

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Matthew J Crabtree

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Candice Sun Hong

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Naeimeh Kamranpour

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Sharon Pitts

9

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Fairooz Kabbinavar

10

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Cecil Patel

11

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Erika von Euw

12

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Alexander Black

13

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Evangelos D Michelakis

14

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Steven M Dubinett

15

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Dennis J Slamon

16

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 January 2014

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Journal of Cancer Research and Clinical Oncology

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

140

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

443-452

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

https://scigraph.springernature.com/pub.10.1007/s00432-014-1583-9

0 references

Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Combination of sulindac and dichloroacetate kills cancer cells via oxidative damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Treatment for mitochondrial disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Mitaplatin increases sensitivity of tumor cells to cisplatin by inducing mitochondrial dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Metabolic modulation of glioblastoma with dichloroacetate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Why do cancers have high aerobic glycolysis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Akt stimulates aerobic glycolysis in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Multidisciplinary management of lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Activation of K+ channels: an essential pathway in programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

On the Origin of Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Toxicity and response criteria of the Eastern Cooperative Oncology Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

23 August 2017

Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

6 September 2017

Dichloroacetate induces apoptosis of epithelial ovarian cancer cells through a mechanism involving modulation of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

6 September 2017

In vitro cytotoxicity of novel platinum-based drugs and dichloroacetate against lung carcinoid cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

14 September 2017

Causes of death of patients with lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

25 June 2018

Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and promising therapeutic applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

25 June 2018

The cellular response to hypoxia: tuning the system with microRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

25 June 2018

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939783

1 September 2018

Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1583-9

21 January 2018

The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1583-9

21 January 2018

Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1583-9

21 January 2018

Plasma concentrations and metabolic effects of intravenous sodium dichloroacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24442098

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-Inducible Factor-1 (HIF-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24442098

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human kinetics of orally and intravenously administered low-dose 1,2-(13)C-dichloroacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24442098

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-014-1583-9

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37612417&oldid=2158849251"