(Q37627319)

21 August 2017

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title

Potential mechanisms involved in the prevention of neurodegenerative diseases by lithium (English)

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21 August 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

Felix Junyent

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

Carme Pelegrí

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

Jordi Vilaplana

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

Mercè Pallàs

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

author name string

Ester Verdaguer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

Marc Yeste-Velasco

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

publication date

1 January 2009

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CNS Neuroscience & Therapeutics

21 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

volume

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

page(s)

333-344

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

14 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

Inositol and IP3 levels regulate autophagy: biology and therapeutic speculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

FOXO transcription factors in ageing and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00086.X

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

1 reference

12 December 2020

Inhibition of excessive neuronal apoptosis by the calcium antagonist amlodipine and antioxidants in cerebellar granule cells.

1 reference

12 December 2020

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

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12 December 2020

Signaling: cellular insights into the pathophysiology of bipolar disorder

1 reference

12 December 2020

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness

1 reference

12 December 2020

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

1 reference

12 December 2020

Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells

1 reference

12 December 2020

Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease

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12 December 2020

Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease

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12 December 2020

Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage

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12 December 2020

Long-term lithium treatment prevents neurotoxic effects of beta-bungarotoxin in primary cultured neurons.

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12 December 2020

p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism

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12 December 2020

Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3

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12 December 2020

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

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12 December 2020

A myocyte enhancer factor 2D (MEF2D) kinase activated during neuronal apoptosis is a novel target inhibited by lithium

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12 December 2020

Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3.

1 reference

12 December 2020

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model.

1 reference

12 December 2020

Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders

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12 December 2020

Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease

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12 December 2020

Lithium prevents colchicine-induced apoptosis in rat cerebellar granule neurons

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12 December 2020

Inhibition of glycogen synthase kinase 3 beta is involved in the resistance to oxidative stress in neuronal HT22 cells

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12 December 2020

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

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12 December 2020

Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax.

1 reference

12 December 2020

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

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12 December 2020

Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo

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12 December 2020

Lithium neuroprotection: molecular mechanisms and clinical implications

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12 December 2020

Does lithium therapy protect against the onset of dementia?

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12 December 2020

Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress

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12 December 2020

Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs

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12 December 2020

Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons

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12 December 2020

Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium

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12 December 2020

Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells.

1 reference

12 December 2020

Lithium chloride increases the production of amyloid-beta peptide independently from its inhibition of glycogen synthase kinase 3.

1 reference

12 December 2020

Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.

1 reference

12 December 2020

The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials

1 reference

12 December 2020

Lithium induces autophagy by inhibiting inositol monophosphatase

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12 December 2020

FOXO transcription factors at the interface between longevity and tumor suppression

1 reference

12 December 2020

Chronic lithium chloride administration attenuates brain NMDA receptor-initiated signaling via arachidonic acid in unanesthetized rats

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12 December 2020

Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8.

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12 December 2020

Cytoprotection by lithium and valproate varies between cell types and cellular stresses

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12 December 2020

Lithium and dementia: a preliminary study

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12 December 2020

Increased oxidative stress and DNA damage in bipolar disorder: A twin-case report

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12 December 2020

Evaluation of acute antiapoptotic effects of Li+ in neuronal cell cultures

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12 December 2020

Chronic lithium treatment has antioxidant properties but does not prevent oxidative damage induced by chronic variate stress.

1 reference

12 December 2020

Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania.

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12 December 2020

Lithium protects ethanol-induced neuronal apoptosis.

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12 December 2020

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

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12 December 2020

Neuronal cell cycle re-entry mediates Alzheimer disease-type changes

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12 December 2020

Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.

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12 December 2020

Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.

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12 December 2020

Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium

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12 December 2020

The Akt-GSK-3 signaling cascade in the actions of dopamine

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12 December 2020

Lithium normalizes elevated intracellular sodium

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12 December 2020

GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder

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12 December 2020

Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania.

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12 December 2020

Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects

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12 December 2020

Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans

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12 December 2020

The complex p25/Cdk5 kinase in neurofibrillary degeneration and neuronal death: the missing link to cell cycle.

1 reference

12 December 2020

In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked?

1 reference

12 December 2020

Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells.

1 reference

12 December 2020

Lithium: a novel treatment for Alzheimer's disease?

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12 December 2020

Increased permeability of blood–brain barrier on the hippocampus of a murine model of senescence

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12 December 2020

Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans

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12 December 2020

GSK-3 inhibitors for Alzheimer's disease.

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12 December 2020

Functional MRI of delayed chronic lithium treatment in rat focal cerebral ischemia

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12 December 2020

Lithium delays progression of amyotrophic lateral sclerosis

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12 December 2020

Lithium, a potential protective drug in Alzheimer's disease

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12 December 2020

Neuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons

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12 December 2020

Apoptotic mechanisms involved in neurodegenerative diseases: experimental and therapeutic approaches

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12 December 2020

Swedish amyloid precursor protein mutation increases cell cycle-related proteins in vitro and in vivo.

1 reference

12 December 2020

GSK-3 beta inhibition and prevention of mitochondrial apoptosis inducing factor release are not involved in the antioxidant properties of SB-415286.

1 reference

12 December 2020

Lithium treatment decreases activities of tau kinases in a murine model of senescence.

1 reference

12 December 2020

Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model

1 reference

12 December 2020

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

1 reference

12 December 2020

Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro

1 reference

12 December 2020

Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies

1 reference

12 December 2020

The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.

1 reference

12 December 2020

Activation of Akt by lithium: pro-survival pathways in aging.

1 reference

12 December 2020

A protective effect of lithium on rat behaviour altered by ibotenic acid lesions of the basal forebrain cholinergic system.

1 reference

12 December 2020

Lithium delays the radiation-induced apoptotic process in external granule cells of mouse cerebellum

1 reference

12 December 2020

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

1 reference

12 December 2020

Effects of chronic lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat.

1 reference

12 December 2020

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

12 December 2020

10.1111/J.1755-5949.2009.00086.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494035&resulttype=core&format=json

14 May 2020

1 reference