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The gates of ion channels and enzymes
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scholarly article
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Europe PubMed Central
PMCID
2867094
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21 August 2017
review article
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Europe PubMed Central
title
The gates of ion channels and enzymes
(English)
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Europe PubMed Central
PMCID
2867094
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21 August 2017
author
J. Andrew McCammon
series ordinal
2
object named as
J Andrew McCammon
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Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
author name string
Huan-Xiang Zhou
series ordinal
1
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PMCID
2867094
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21 August 2017
language of work or name
English
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publication date
18 November 2009
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PMCID
2867094
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21 August 2017
number of pages
7
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published in
Trends in Biochemical Sciences
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Europe PubMed Central
PMCID
2867094
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21 August 2017
volume
35
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Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
page(s)
179-185
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Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
issue
3
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Europe PubMed Central
PMCID
2867094
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21 August 2017
cites work
Structure of a tetrameric MscL in an expanded intermediate state
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23 August 2017
Conformational heterogeneity of the M2 proton channel and a structural model for channel activation
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PubMed Central
reference URL
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retrieved
23 August 2017
Multiple pathways guide oxygen diffusion into flavoenzyme active sites
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PubMed Central
reference URL
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23 August 2017
Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
23 August 2017
High-resolution structure of the open NaK channel
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PubMed Central
reference URL
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23 August 2017
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
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PubMed Central
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23 August 2017
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
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PubMed Central
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23 August 2017
Uncovering channels in photosystem II by computer modelling: current progress, future prospects, and lessons from analogous systems.
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23 August 2017
Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition
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PubMed Central
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23 August 2017
The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †
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PubMed Central
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23 August 2017
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
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PubMed Central
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23 August 2017
Structural basis for the function and inhibition of an influenza virus proton channel
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PubMed Central
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23 August 2017
Structure and mechanism of the M2 proton channel of influenza A virus
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PubMed Central
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23 August 2017
Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
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PubMed Central
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23 August 2017
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera
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PubMed Central
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23 August 2017
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site
1 reference
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PubMed Central
reference URL
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23 August 2017
Atomic structure of a Na+- and K+-conducting channel
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PubMed Central
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23 August 2017
Investigating the putative glycine hinge in Shaker potassium channel.
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23 August 2017
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism
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PubMed Central
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23 August 2017
Enzymes with molecular tunnels
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PubMed Central
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23 August 2017
Structure and gating mechanism of the acetylcholine receptor pore
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
A cysteine scan of the inner vestibule of cyclic nucleotide-gated channels reveals architecture and rearrangement of the pore
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Crystal structure of a bifunctional aldolase-dehydrogenase: sequestering a reactive and volatile intermediate
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Crystal structure of the potassium channel KirBac1.1 in the closed state
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity
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PubMed Central
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23 August 2017
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.
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PubMed Central
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23 August 2017
The closed state of a H+ channel helical bundle combining precise orientational and distance restraints from solid state NMR
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PubMed Central
reference URL
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23 August 2017
Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
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23 August 2017
Molecular dynamics of acetylcholinesterase
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PubMed Central
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23 August 2017
Analysis of a 10-ns molecular dynamics simulation of mouse acetylcholinesterase
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PubMed Central
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23 August 2017
Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Channeling of substrates and intermediates in enzyme-catalyzed reactions
1 reference
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PubMed Central
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23 August 2017
Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
The gating mechanism of the large mechanosensitive channel MscL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis
1 reference
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PubMed Central
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23 August 2017
Conformation gating as a mechanism for enzyme specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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23 August 2017
Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium.
1 reference
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PubMed Central
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23 August 2017
Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein
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23 August 2017
Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis
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PubMed Central
reference URL
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23 August 2017
Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes
1 reference
stated in
PubMed Central
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6 September 2017
On the oxygen reactivity of flavoprotein oxidases: an oxygen access tunnel and gate in brevibacterium sterolicum cholesterol oxidase.
1 reference
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PubMed Central
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14 September 2017
Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome
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PubMed Central
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14 September 2017
Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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25 June 2018
The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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25 June 2018
The open pore conformation of potassium channels
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
25 June 2018
Glucosamine synthetase from Escherichia coli: purification, properties, and glutamine-utilizing site location.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
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25 June 2018
Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
1 September 2018
Channel opening motion of alpha7 nicotinic acetylcholine receptor as suggested by normal mode analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
1 September 2018
Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
1 September 2018
Rotational movement during cyclic nucleotide-gated channel opening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
1 September 2018
Open "back door" in a molecular dynamics simulation of acetylcholinesterase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867094
retrieved
1 September 2018
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19926290
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19926290
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1016/J.TIBS.2009.10.007
1 reference
stated in
Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
PMCID
2867094
1 reference
stated in
Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
PubMed ID
19926290
1 reference
stated in
Europe PubMed Central
PMCID
2867094
retrieved
21 August 2017
ResearchGate publication ID
38113834
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