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English
The role of autophagy in tumour development and cancer therapy.
scientific article published on 02 December 2009
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
review article
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stated in
Europe PubMed Central
title
The role of autophagy in tumour development and cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
main subject
autophagy
0 references
author
Kevin M Ryan
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
author name string
Mathias T Rosenfeldt
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
language of work or name
English
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publication date
2 December 2009
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Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
published in
Expert Reviews in Molecular Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
volume
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
page(s)
e36
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
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23 August 2017
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23 August 2017
Ras, PI(3)K and mTOR signalling controls tumour cell growth
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23 August 2017
A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
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23 August 2017
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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23 August 2017
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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23 August 2017
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23 August 2017
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
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23 August 2017
The role of autophagy in cancer development and response to therapy.
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23 August 2017
Autophagy in metazoans: cell survival in the land of plenty
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
23 August 2017
The coordinate regulation of the p53 and mTOR pathways in cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
23 August 2017
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
The expanding TOR signaling network
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
23 August 2017
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Splicing DNA-damage responses to tumour cell death.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
The role of autophagy during the early neonatal starvation period
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Two ubiquitin-like conjugation systems essential for autophagy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Epigenetic regulation of ARHI in breast and ovarian cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
23 August 2017
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
23 August 2017
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
The Hallmarks of Cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
p53 and human cancer: the first ten thousand mutations.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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23 August 2017
Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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14 September 2017
Stimulation of autophagy by the p53 target gene Sestrin2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
14 September 2017
Alkylating DNA damage stimulates a regulated form of necrotic cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
28 September 2017
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
25 June 2018
Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
25 June 2018
Mutant p53 protein localized in the cytoplasm inhibits autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
1 September 2018
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
1 September 2018
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
1 September 2018
A negative feedback signaling network underlies oncogene-induced senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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1 September 2018
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
retrieved
1 September 2018
Ras is involved in the negative control of autophagy through the class I PI3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811398
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1 September 2018
Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1017%2FS1462399409001306
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21 January 2018
Growth factor signaling permits hypoxia-induced autophagy by a HIF1α-dependent, BNIP3/3L-independent transcriptional program in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS1462399409001306
retrieved
21 January 2018
Identifiers
DOI
10.1017/S1462399409001306
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PMC publication ID
2811398
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PubMed publication ID
19951459
1 reference
stated in
Europe PubMed Central
PMC publication ID
2811398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951459%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
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