(Q37643931)

English

c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.

scientific article published on 13 January 2014

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5 March 2020

c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver (English)

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5 March 2020

apoptotic process

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5 March 2020

André L. Simão

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5 March 2020

Diane M. Pereira

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5 March 2020

Pedro M Borralho

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5 March 2020

8

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5 March 2020

Duarte Miguel Sacramento Ferreira

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Duarte M S Ferreira

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5 March 2020

Pedro M Rodrigues

3

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5 March 2020

Cecília M P Rodrigues

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5 March 2020

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13 January 2014

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5 March 2020

Molecular and Cellular Biology

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5 March 2020

34

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5 March 2020

6

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5 March 2020

1100-1120

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1 reference

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1 reference

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MiR-122 in hepatic function and liver diseases

1 reference

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Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity

1 reference

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23 August 2017

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Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid

1 reference

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JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis

1 reference

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23 August 2017

The miR-34 family in cancer and apoptosis

1 reference

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23 August 2017

MiR-34, SIRT1 and p53: the feedback loop

1 reference

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23 August 2017

How does SIRT1 affect metabolism, senescence and cancer?

1 reference

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23 August 2017

miR-34a repression of SIRT1 regulates apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958031

23 August 2017

A microRNA component of the p53 tumour suppressor network

1 reference

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23 August 2017

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

1 reference

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23 August 2017

Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain

1 reference

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23 August 2017

Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.

1 reference

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23 August 2017

Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway

1 reference

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23 August 2017

Bile acids as carcinogens in human gastrointestinal cancers

1 reference

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JNK2: a negative regulator of cellular proliferation

1 reference

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23 August 2017

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

1 reference

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Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors

1 reference

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23 August 2017

A central role for JNK in obesity and insulin resistance

1 reference

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23 August 2017

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

1 reference

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23 August 2017

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress

1 reference

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23 August 2017

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

1 reference

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23 August 2017

Control of cell cycle progression by c-Jun is p53 dependent

1 reference

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23 August 2017

MEKK1/JNK signaling stabilizes and activates p53.

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A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

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23 August 2017

Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production

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23 August 2017

A cytoplasmic inhibitor of the JNK signal transduction pathway

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23 August 2017

Selective interaction of JNK protein kinase isoforms with transcription factors

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23 August 2017

Suppression of human colorectal carcinoma cell growth by wild-type p53

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23 August 2017

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Role of the JNK pathway in human diseases

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6 September 2017

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6 September 2017

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6 September 2017

Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes

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25 June 2018

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1 reference

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25 June 2018

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1 reference

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25 June 2018

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25 June 2018

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1 reference

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1 September 2018

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1 reference

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1 September 2018

Bile acid levels are increased in the liver of patients with steatohepatitis

1 reference

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1 September 2018

Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation

1 reference

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1 September 2018

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

1 reference

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1 September 2018

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1 reference

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1 September 2018

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1 reference

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1 September 2018

Posttranscriptional regulation of mRNA levels in rat liver associated with deoxycholic acid feeding.

1 reference

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1 September 2018

The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation.

1 reference

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1 September 2018

Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes

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3 December 2018

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3 December 2018

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24421392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/24421392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00420-13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421392%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421392%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421392%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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