(Q38349877)

English

Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes

scientific article published on 26 September 2003

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scholarly article

1 reference

Europe PubMed Central

2 September 2017

Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes (English)

1 reference

Europe PubMed Central

2 September 2017

apoptotic process

1 reference

based on heuristic

inferred from title

4

object named as

Betsy T Kren

1 reference

Europe PubMed Central

2 September 2017

Clifford J Steer

5

object named as

Clifford J Steer

1 reference

Europe PubMed Central

2 September 2017

author name string

Susana Sola

1

1 reference

Europe PubMed Central

2 September 2017

Xiaoming Ma

2

1 reference

Europe PubMed Central

2 September 2017

Rui E Castro

3

1 reference

Europe PubMed Central

2 September 2017

Cecilia M P Rodrigues

6

1 reference

Europe PubMed Central

2 September 2017

language of work or name

0 references

publication date

26 September 2003

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Europe PubMed Central

2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

2 September 2017

278

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Europe PubMed Central

2 September 2017

49

1 reference

Europe PubMed Central

2 September 2017

48831-48838

1 reference

Europe PubMed Central

2 September 2017

Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Mechanisms of TGF-beta-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The retinoblastoma protein: more than a tumor suppressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

E2F-1 induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Control of pRB phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

E2F-1-induced p53-independent apoptosis in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Distinct roles for E2F proteins in cell growth control and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Apaf-1 is a transcriptional target for E2F and p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Functional properties of a Drosophila homolog of the E2F1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Identification of a growth suppression domain within the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

How cells read TGF-beta signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Stress signals utilize multiple pathways to stabilize p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Role of caspases and possible involvement of retinoblastoma protein during TGFbeta-mediated apoptosis of human B lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300468200

21 January 2018

Identifiers

10.1074/JBC.M300468200

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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