(Q37673257)

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Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials.

scientific article published on 19 February 2017

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3 April 2020

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3 October 2022

Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials (English)

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3 April 2020

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autism spectrum disorder

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13 March 2019

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19 November 2019

omega-3 fatty acid

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28 April 2021

systematic review

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inferred from title

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Welma Stonehouse

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3 October 2022

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19 November 2019

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19 November 2019

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Peripheral Inflammatory Markers Contributing to Comorbidities in Autism.

1 reference

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23 August 2017

Identification of Biomarkers of Impaired Sensory Profiles among Autistic Patients

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23 August 2017

Omega-3 and Omega-6 Polyunsaturated Fatty Acid Levels and Correlations with Symptoms in Children with Attention Deficit Hyperactivity Disorder, Autistic Spectrum Disorder and Typically Developing Controls

1 reference

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23 August 2017

Plasma Oxytocin in Children with Autism and Its Correlations with Behavioral Parameters in Children and Parents.

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23 August 2017

Maternal diet of polyunsaturated fatty acid altered the cell proliferation in the dentate gyrus of hippocampus and influenced glutamatergic and serotoninergic systems of neonatal female rats

1 reference

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23 August 2017

Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages

1 reference

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23 August 2017

Nutritional and Metabolic Biomarkers in Autism Spectrum Disorders: An Exploratory Study

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23 August 2017

Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans

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23 August 2017

Potential serum biomarkers from a metabolomics study of autism

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23 August 2017

Predictors of placebo response in pharmacological and dietary supplement treatment trials in pediatric autism spectrum disorder: a meta-analysis

1 reference

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23 August 2017

Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells

1 reference

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23 August 2017

Complementary and Alternative Therapies for Autism Spectrum Disorder

1 reference

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23 August 2017

Autistic children exhibit decreased levels of essential Fatty acids in red blood cells

1 reference

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23 August 2017

Ethnicity, sex, FADS genetic variation, and hormonal contraceptive use influence delta-5- and delta-6-desaturase indices and plasma docosahexaenoic acid concentration in young Canadian adults: a cross-sectional study

1 reference

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23 August 2017

Cerebellar gray matter and lobular volumes correlate with core autism symptoms.

1 reference

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23 August 2017

Reduced levels of plasma polyunsaturated fatty acids and serum carnitine in autistic children: relation to gastrointestinal manifestations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

23 August 2017

Brain-Derived Neurotrophic Factor in children with Autism Spectrum Disorder

1 reference

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23 August 2017

White matter correlates of sensory processing in autism spectrum disorders

1 reference

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23 August 2017

Fatty acid metabolism in carriers of apolipoprotein E epsilon 4 allele: is it contributing to higher risk of cognitive decline and coronary heart disease?

1 reference

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23 August 2017

Nutritional status survey of children with autism and typically developing children aged 4-6 years in Heilongjiang Province, China

1 reference

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23 August 2017

Reduction in behavior problems with omega-3 supplementation in children aged 8-16 years: a randomized, double-blind, placebo-controlled, stratified, parallel-group trial

1 reference

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23 August 2017

Does consumption of LC omega-3 PUFA enhance cognitive performance in healthy school-aged children and throughout adulthood? Evidence from clinical trials

1 reference

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23 August 2017

Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies

1 reference

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23 August 2017

Internet-based, randomized, controlled trial of omega-3 fatty acids for hyperactivity in autism

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23 August 2017

Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism

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23 August 2017

Deficits in bioenergetics and impaired immune response in granulocytes from children with autism

1 reference

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23 August 2017

Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort

1 reference

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23 August 2017

Determinants of erythrocyte omega-3 fatty acid content in response to fish oil supplementation: a dose-response randomized controlled trial

1 reference

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23 August 2017

Gastrointestinal problems in children with autism, developmental delays or typical development

1 reference

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23 August 2017

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism.

1 reference

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23 August 2017

Baseline factors predicting placebo response to treatment in children and adolescents with autism spectrum disorders: a multisite randomized clinical trial

1 reference

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23 August 2017

Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids

1 reference

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23 August 2017

Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features

1 reference

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Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [¹H]MRS study.

1 reference

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23 August 2017

Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white matter injury after experimental traumatic brain injury.

1 reference

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Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder

1 reference

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Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism.

1 reference

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23 August 2017

Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008

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23 August 2017

Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)

1 reference

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23 August 2017

A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development

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23 August 2017

Solving the autism puzzle a few pieces at a time

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23 August 2017

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

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A study of nuclear transcription factor-kappa B in childhood autism

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23 August 2017

Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism.

1 reference

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23 August 2017

Impaired plasma phospholipids and relative amounts of essential polyunsaturated fatty acids in autistic patients from Saudi Arabia

1 reference

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23 August 2017

Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia

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23 August 2017

Changes in prefrontal axons may disrupt the network in autism

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23 August 2017

A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder

1 reference

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23 August 2017

Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study

1 reference

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The severity of autism is associated with toxic metal body burden and red blood cell glutathione levels

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Phenotypic expression of autoimmune autistic disorder (AAD): a major subset of autism.

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23 August 2017

Omega-3 fatty acids for autistic spectrum disorder: a systematic review

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23 August 2017

Implications of clinical trial design on sample size requirements

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23 August 2017

Regional gray matter volumetric changes in autism associated with social and repetitive behavior symptoms

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23 August 2017

Gray matter abnormalities in autism spectrum disorder revealed by T2 relaxation

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n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases

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23 August 2017

Dietary fatty acids and membrane protein function

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23 August 2017

Essential fatty acids and phospholipase A2 in autistic spectrum disorders

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23 August 2017

Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatment

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23 August 2017

Pervasive Developmental Disorders in Preschool Children

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23 August 2017

Red blood cell fatty acid compositions in a patient with autistic spectrum disorder: a characteristic abnormality in neurodevelopmental disorders?

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23 August 2017

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23 August 2017

Monoamines (serotonin and catecholamines) and their derivatives in infantile autism: age-related changes and drug effects

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23 August 2017

Omega-6 to Omega-3 Fatty Acid Ratio in Patients with ADHD: A Meta-Analysis

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6 September 2017

Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression

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6 September 2017

Abnormal fatty acids in Canadian children with autism

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6 September 2017

Omega-3 fatty acids in the management of autism spectrum disorders: findings from an open-label pilot study in Singapore

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6 September 2017

Omega-3 polyunsaturated fatty acids inhibit the increase in cytokines and chemotactic factors induced in vitro by lymph fluid from an intestinal ischemia-reperfusion injury model

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6 September 2017

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health

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6 September 2017

Meta-regression analysis of placebo response in antipsychotic trials, 1970-2010.

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6 September 2017

Dietary methods and biomarkers of omega 3 fatty acids: a systematic review

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6 September 2017

Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries.

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14 September 2017

Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation

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14 September 2017

Fatty acid and phospholipase A2 plasma levels in children with autism

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28 September 2017

Omega-3 fatty acid and ADHD: blood level analysis and meta-analytic extension of supplementation trials

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25 June 2018

Impact of nutrition on serum levels of docosahexaenoic acid among Omani children with autism.

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25 June 2018

Lipid mediators in plasma of autism spectrum disorders

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25 June 2018

Brain serotonin and dopamine transporter bindings in adults with high-functioning autism.

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25 June 2018

Omega 3 fatty acid treatment in autism

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25 June 2018

Behavioral effects of omega-3 fatty acid supplementation in young adults with severe autism: an open label study

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25 June 2018

Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

25 June 2018

Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

25 June 2018

Competitive Interaction Between Plasma Omega-3 Fatty Acids and Arachidonic Acid is Related to Down-Regulation of A Signaling Mediator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Increased ω-3 polyunsaturated fatty acid/arachidonic acid ratios and upregulation of signaling mediator in individuals with autism spectrum disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

A Single Bolus of Docosahexaenoic Acid Promotes Neuroplastic Changes in the Innervation of Spinal Cord Interneurons and Motor Neurons and Improves Functional Recovery after Spinal Cord Injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Pituitary Adenylate Cyclase-Activating Polypeptide Disrupts Motivation, Social Interaction, and Attention in Male Sprague Dawley Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Brain derived neurotrophic factor (BDNF) and autism spectrum disorders (ASD) in childhood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Dietary docosahexaenoic acid supplementation in children with autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Long-chain omega-3 fatty acids improve brain function and structure in older adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Measurement tools and target symptoms/skills used to assess treatment response for individuals with autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Nutritional factors in the pathobiology of autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Effects of large doses of arachidonic acid added to docosahexaenoic acid on social impairment in individuals with autism spectrum disorders: a double-blind, placebo-controlled, randomized trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Influence of gender on DHA synthesis: the response of rat liver to low dietary α-linolenic acid evidences higher ω3 ∆4-desaturation index in females

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

The prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected members.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Omega-3 fatty acids deprivation affects ontogeny of glutamatergic synapses in rats: relevance for behavior alterations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

The fatty acid compositions of erythrocyte and plasma polar lipids in children with autism, developmental delay or typically developing controls and the effect of fish oil intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Novel plasma phospholipid biomarkers of autism: mitochondrial dysfunction as a putative causative mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Plasma fatty acid profiles in autism: a case-control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Lipid profile, fatty acid composition and pro- and anti-oxidant status in pediatric patients with attention-deficit/hyperactivity disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurones throughout development and in aged animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Role of polyunsaturated fatty acids in the management of Egyptian children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

A preliminary study on screening prevalence of pervasive developmental disorder in schoolchildren in Iran.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Omega-3 fatty acids supplementation in children with autism: a double-blind randomized, placebo-controlled pilot study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Polyunsaturated fatty acids: do they have a role in the pathophysiology of autism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Fatty acid compositions of red blood cell phospholipids in children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Effects of docosahexaenoic acid on the survival and neurite outgrowth of rat cortical neurons in primary cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Docosahexaenoic acid promotes neurite growth in hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Evidence that eicosapentaenoic acid is effective in treating autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Reduced erythrocyte membrane essential fatty acids and increased lipid peroxides in schizophrenia at the never-medicated first-episode of psychosis and after years of treatment with antipsychotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Plasma fatty acid levels in autistic children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Quantitative determination of plasma c8-c26 total fatty acids for the biochemical diagnosis of nutritional and metabolic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5331586

1 September 2018

Fetomaternal alloimmune thrombocytopenia presenting as intracerebral bleeding in utero

1 reference

https://api.crossref.org/works/10.3390%2FNU9020155

21 January 2018

Comparison between plasma and erythrocyte fatty acid content as biomarkers of fatty acid intake in US women

1 reference

https://pubmed.ncbi.nlm.nih.gov/28218722

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent fatty acid composition of erythrocyte membrane phospholipids in healthy children

1 reference

https://pubmed.ncbi.nlm.nih.gov/28218722

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic dietary alpha-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/28218722

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential fatty acids, DHA and human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/28218722

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU9020155

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28218722%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28218722%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28218722%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

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