(Q37681529)

English

Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing

scientific article published on 06 March 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

22 August 2017

Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

computational model

1 reference

based on heuristic

Jeroen E Guikema

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Polina Reshetova

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Barbera D C van Schaik

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paul L Klarenbeek

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Marieke E Doorenspleet

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Rebecca E E Esveldt

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paul-Peter Tak

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Antoine H C van Kampen

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

6 March 2017

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Europe PubMed Central

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22 August 2017

Frontiers in Immunology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

221

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

describes a project that uses

object named as

ggplot

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

1 reference

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23 August 2017

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

1 reference

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23 August 2017

High-quality full-length immunoglobulin profiling with unique molecular barcoding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

MEANS: python package for Moment Expansion Approximation, iNference and Simulation.

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23 August 2017

Visualizing antibody affinity maturation in germinal centers

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23 August 2017

A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

1 reference

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23 August 2017

Practical guidelines for B-cell receptor repertoire sequencing analysis

1 reference

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23 August 2017

IMonitor: A Robust Pipeline for TCR and BCR Repertoire Analysis

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23 August 2017

The analysis of clonal expansions in normal and autoimmune B cell repertoires

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

IgRepertoireConstructor: a novel algorithm for antibody repertoire construction and immunoproteogenomics analysis

1 reference

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23 August 2017

IMSEQ--a fast and error aware approach to immunogenetic sequence analysis

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23 August 2017

Dynamics of B cells in germinal centres

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23 August 2017

Characterizing immune repertoires by high throughput sequencing: strategies and applications.

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B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

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Immunoglobulin and T Cell Receptor Genes: IMGT(®) and the Birth and Rise of Immunoinformatics

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23 August 2017

Persistence and selection of an expanded B-cell clone in the setting of rituximab therapy for Sjögren's syndrome

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Convergent antibody signatures in human dengue

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23 August 2017

Germinal center B cells govern their own fate via antibody feedback

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23 August 2017

Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

Germinal center selection and the development of memory B and plasma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

Germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

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23 August 2017

Novel approaches for identifying target antigens of autoreactive human B and T cells

1 reference

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23 August 2017

Recirculation of germinal center B cells: a multilevel selection strategy for antibody maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes

1 reference

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23 August 2017

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

A mathematical model for the germinal center morphology and affinity maturation

1 reference

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23 August 2017

BLAT—The BLAST-Like Alignment Tool

1 reference

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23 August 2017

Structural insights into the evolution of an antibody combining site

1 reference

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23 August 2017

Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts.

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23 August 2017

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

1 reference

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23 August 2017

Germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte development

1 reference

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23 August 2017

Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

23 August 2017

Identification of Antigen-Specific B-Cell Receptor Sequences from the Total B-Cell Repertoire.

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6 September 2017

Sequencing the functional antibody repertoire--diagnostic and therapeutic discovery

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6 September 2017

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination.

1 reference

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6 September 2017

Determining germinal centre B cell fate.

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6 September 2017

Increasing viral dose causes a reversal in CD8+ T cell immunodominance during primary influenza infection due to differences in antigen presentation, T cell avidity, and precursor numbers.

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6 September 2017

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

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28 September 2017

The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales

1 reference

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25 June 2018

Clonal selection in the germinal centre by regulated proliferation and hypermutation

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25 June 2018

Broad volume distributions indicate nonsynchronized growth and suggest sudden collapses of germinal center B cell populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

25 June 2018

Predicted and inferred waiting times for key mutations in the germinal centre reaction: evidence for stochasticity in selection

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25 June 2018

Clone: a Monte-Carlo computer simulation of B cell clonal expansion, somatic mutation, and antigen-driven selection

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25 June 2018

Maturation of the immune response in germinal centers

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25 June 2018

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

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25 June 2018

Igs expressed by chronic lymphocytic leukemia B cells show limited binding-site structure variability.

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1 September 2018

Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337809

1 September 2018

Measuring antibody-antigen binding kinetics using surface plasmon resonance.

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1 September 2018

Is there a typical germinal center? A large-scale immunohistological study on the cellular composition of germinal centers during the hapten-carrier-driven primary immune response in mice

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1 September 2018

Human T-cell memory consists mainly of unexpanded clones.

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1 September 2018

Antigen-driven selection in germinal centers as reflected by the shape characteristics of immunoglobulin gene lineage trees: a large-scale simulation study.

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1 September 2018

IgTree: creating Immunoglobulin variable region gene lineage trees.

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1 September 2018

Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center

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1 September 2018

Toward quantitative simulation of germinal center dynamics: biological and modeling insights from experimental validation

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1 September 2018

Improved methods for detecting selection by mutation analysis of Ig V region sequences

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21 January 2018

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

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21 January 2018

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12 December 2020

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inferred from PubMed ID database lookup

Reconciling repertoire shift with affinity maturation: the role of deleterious mutations

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell kinetics of the germinal center reaction - a stathmokinetic study

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A possible role of chemotaxis in germinal center formation

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FIMMU.2017.00221

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28321219%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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