(Q37693083)

22 August 2017

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title

Crossing paths: interactions between the cell death machinery and growth factor survival signals (English)

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22 August 2017

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Paul G Ekert

3

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author name string

Gabriela Brumatti

series ordinal

1

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22 August 2017

Marika Salmanidis

series ordinal

2

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22 August 2017

publication date

16 February 2010

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Cellular and Molecular Life Sciences

22 August 2017

published in

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22 August 2017

volume

67

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22 August 2017

issue

10

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22 August 2017

page(s)

1619-1630

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0288-8

22 August 2017

exact match

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cites work

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

IL-5 and granulocyte-macrophage colony-stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0288-8

Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells

21 January 2018

1 reference

12 December 2020

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

12 December 2020

Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation.

1 reference

12 December 2020

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

1 reference

12 December 2020

Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis

1 reference

12 December 2020

Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival

1 reference

12 December 2020

Blood cells with reduced mitochondrial membrane potential and cytosolic cytochrome C can survive and maintain clonogenicity given appropriate signals to suppress apoptosis.

1 reference

12 December 2020

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

1 reference

12 December 2020

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma

1 reference

12 December 2020

Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation

1 reference

12 December 2020

Growth of factor-dependent hemopoietic precursor cell lines

1 reference

12 December 2020

The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias

1 reference

12 December 2020

Granulocyte-macrophage colony-stimulating factor is an endogenous regulator of cell proliferation in juvenile chronic myelogenous leukemia

1 reference

12 December 2020

Myelodysplastic and myeloproliferative disorders in children.

1 reference

12 December 2020

Testicular degeneration in Bclw-deficient mice

1 reference

12 December 2020

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation

1 reference

12 December 2020

Activities of granulocyte-macrophage colony-stimulating factor revealed by gene transfer and gene knockout studies

1 reference

12 December 2020

Multisite phosphorylation regulates Bim stability and apoptotic activity

1 reference

12 December 2020

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors

1 reference

12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

12 December 2020

The role of MAP kinase kinase in interleukin-3 stimulation of proliferation

1 reference

12 December 2020

Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation

1 reference

12 December 2020

Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression

1 reference

12 December 2020

The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain

1 reference

12 December 2020

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

1 reference

12 December 2020

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1.

1 reference

12 December 2020

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

12 December 2020

Saturation mutagenesis of the beta subunit of the human granulocyte-macrophage colony-stimulating factor receptor shows clustering of constitutive mutations, activation of ERK MAP kinase and STAT pathways, and differential beta subunit tyrosine [...]

1 reference

12 December 2020

Mapping the intracytoplasmic regions of the alpha granulocyte-macrophage colony-stimulating factor receptor necessary for cell growth regulation.

1 reference

12 December 2020

Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors

1 reference

12 December 2020

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

12 December 2020

Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.

1 reference

12 December 2020

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

12 December 2020

Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation

1 reference

12 December 2020

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

1 reference

12 December 2020

Role of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in the development of an acute neutrophil inflammatory response in mice

1 reference

12 December 2020

Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

1 reference

12 December 2020

Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis.

1 reference

12 December 2020

The Hallmarks of Cancer

1 reference

12 December 2020

bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia.

1 reference

12 December 2020

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

12 December 2020

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

12 December 2020

Bim is a suppressor of Myc-induced mouse B cell leukemia

1 reference

12 December 2020

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

1 reference

12 December 2020

NF-kappaB1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms

1 reference

12 December 2020

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

1 reference

12 December 2020

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

1 reference

12 December 2020

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

12 December 2020

Mcl-1 deficiency results in peri-implantation embryonic lethality

1 reference

12 December 2020

Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation

1 reference

12 December 2020

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

12 December 2020

Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions

1 reference

12 December 2020

bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death

1 reference

12 December 2020

The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

1 reference

12 December 2020

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

1 reference

12 December 2020

Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.

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12 December 2020

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

1 reference

12 December 2020

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

1 reference

12 December 2020

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

12 December 2020

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

1 reference

12 December 2020

Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia

1 reference

12 December 2020

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

1 reference

12 December 2020

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

12 December 2020

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.

1 reference

12 December 2020

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

12 December 2020

Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

1 reference

12 December 2020

BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

1 reference

12 December 2020

Role of Bax in apoptosis of IL-3-dependent cells.

1 reference

12 December 2020

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

12 December 2020

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

1 reference

12 December 2020

Role of cytokines in the treatment of acute leukemias: a review

1 reference

12 December 2020

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

12 December 2020

Cytokine receptors and hematopoietic differentiation

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12 December 2020

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3

1 reference

12 December 2020

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

1 reference

12 December 2020

Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors

1 reference

12 December 2020

GM-CSF rescues TF-1 cells from growth factor withdrawal-induced, but not differentiation-induced apoptosis: the role of BCL-2 and MCL-1.

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

Phosphorylation of Bcl2 and regulation of apoptosis

1 reference

12 December 2020

IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection

1 reference

12 December 2020

Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750

1 reference

12 December 2020

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells

1 reference

12 December 2020

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

1 reference

12 December 2020

Effects of recombinant human interleukin-3 on CD34-enriched normal hematopoietic progenitors and on myeloblastic leukemia cells

1 reference

12 December 2020

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

12 December 2020

The survival kinases Akt and Pim as potential pharmacological targets

1 reference

12 December 2020

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis

1 reference

12 December 2020

Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation

1 reference

12 December 2020

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

12 December 2020

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

1 reference

12 December 2020

Interleukin-3 receptor in acute leukemia

1 reference

12 December 2020

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

1 reference

12 December 2020

Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal

1 reference

12 December 2020

JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.

1 reference

12 December 2020

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

1 reference

12 December 2020

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

1 reference

12 December 2020

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

12 December 2020

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

1 reference

12 December 2020

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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12 December 2020

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

1 reference

12 December 2020

Apoptosis by IL-2 deprivation in human CD8+ T cell blasts predominates over death receptor ligation, requires Bim expression and is associated with Mcl-1 loss

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12 December 2020

Ras is not required for the interleukin 3-induced proliferation of a mouse pro-B cell line, BaF3.

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12 December 2020

Transgenic mice as models of hemopoiesis

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12 December 2020

The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death

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12 December 2020

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

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12 December 2020

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

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12 December 2020

IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils

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12 December 2020

IL-3 augments TCR-mediated responses of type 2 CD4 T cells

1 reference

12 December 2020

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

1 reference

12 December 2020

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

12 December 2020

IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line

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12 December 2020

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

1 reference

12 December 2020

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

12 December 2020

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

1 reference

12 December 2020

10.1007/S00018-010-0288-8

Identifiers

DOI

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22 August 2017

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