(Q37698404)

22 August 2017

1 reference

title

The influence of genetic polymorphisms on population variability in six xenobiotic-metabolizing enzymes (English)

1 reference

22 August 2017

6

Kathryn Z Guyton

1 reference

22 August 2017

Gary Ginsberg

1

1 reference

22 August 2017

Susan Smolenski

2

1 reference

22 August 2017

Patricia Neafsey

3

1 reference

22 August 2017

Dale Hattis

4

1 reference

22 August 2017

Katy Walker

5

1 reference

22 August 2017

Douglas O Johns

7

1 reference

22 August 2017

Babasaheb Sonawane

8

1 reference

22 August 2017

language of work or name

1 reference

1 January 2009

1 reference

Journal of Toxicology and Environmental Health Part B: Critical Reviews

22 August 2017

1 reference

22 August 2017

12

1 reference

22 August 2017

5-6

1 reference

22 August 2017

307-333

1 reference

Improved understanding of genetic and genomic influences on drug disposition and action : implications for children

22 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Modeling human interindividual variability in metabolism and risk: the example of 4-aminobiphenyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic basis of toxic reactions to drugs and chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Pharmacogenetics of cytochrome p4502D6: genetic background and clinical implication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Preliminary phenotypic map of chromosome 4p16 based on 4p deletions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Increased influence of genetic variation on PON1 activity in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Development of a physiologically based pharmacokinetic model for chloroform

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Modulation of paraoxonase (PON1) activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Polymorphism of xenobiotic-metabolizing enzymes and excretion of styrene-specific mercapturic acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Effects of glutathione transferase theta polymorphism on the risk estimates of dichloromethane to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Pharmacogenomics: translating functional genomics into rational therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Population distribution of aldehyde dehydrogenase-2 genetic polymorphism: implications for risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The influence of polymorphisms of glutathione S-transferases M1 and M3 on the development of human urothelial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic polymorphisms in assessing interindividual variability in delivered dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Functional characterization of three human cytochrome p450 2E1 variants with amino acid substitutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

21 January 2018

Glutathione transferases

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Functional consequences of polymorphism of xenobiotic metabolising enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

A Bayesian analysis of the influence of GSTT1 polymorphism on the cancer risk estimate for dichloromethane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Extrapolation of in vitro enzyme induction data to humans in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Association of ALDH2 polymorphism with sensitivity to acetaldehyde-induced micronuclei and facial flushing after alcohol intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Mammalian class theta GST and differential susceptibility to carcinogens: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Cytochrome P450-dependent metabolism of trichloroethylene: interindividual differences in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The impact of cytochrome P450 2E1-dependent metabolic variance on a risk-relevant pharmacokinetic outcome in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Polymorphic hydroxylation of Debrisoquine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic polymorphisms in human drug metabolic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Polymorphism of drug-metabolizing enzymes in relation to individual susceptibility to industrial chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Ethnic and genetic differences in metabolism genes and risk of toxicity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

In vivo and in vitro studies of perchloroethylene metabolism for physiologically based pharmacokinetic modeling in rats, mice, and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Toxicokinetics in infants and children in relation to the ADI and TDI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Evidence for the activation of organophosphate pesticides by cytochromes P450 3A4 and 2D6 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The Role of Human Glutathione Transferases and Epoxide Hydrolases in the Metabolism of Xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Drug metabolism polymorphisms as modulators of cancer susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Impaired expression of CYP2D6 in intermediate metabolizers carrying the *41 allele caused by the intronic SNP 2988G>A: evidence for modulation of splicing events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Role of the genetic polymorphisms in the 5'-flanking region for transcriptional regulation of the human CYP2E1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Association between genetic polymorphisms and biomarkers in styrene-exposed workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

N-acetyltransferase-2 and medical history in bladder cancer cases with a suspected occupational disease (BK 1301) in Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism in bladder cancer cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

N-Acetyltransferase 1 in Colon and Rectal Cancer Cases from an Industrialized Area

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400903158318

10.1080/10937400903158318

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference