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Mechanisms of action of non-steroidal anti-inflammatory drugs for the prevention of Alzheimer's disease.
scientific article published on April 2010
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Europe PubMed Central
PMCID
4312283
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
review article
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stated in
Europe PubMed Central
title
Mechanisms of action of non-steroidal anti-inflammatory drugs for the prevention of Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
main subject
inflammation
0 references
Alzheimer's disease
0 references
prevention
1 reference
based on heuristic
inferred from title
author
Sally A Frautschy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author name string
Greg M Cole
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
publication date
1 April 2010
1 reference
stated in
Europe PubMed Central
PMCID
4312283
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
published in
CNS and Neurological Disorders
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stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
9
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
140-148
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stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Does NSAID use modify cognitive trajectories in the elderly? The Cache County study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Lack of specific amyloid-beta(1-42) suppression by nonsteroidal anti-inflammatory drugs in young, plaque-free Tg2576 mice and in guinea pig neuronal cultures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Inflammatory proteins in plasma and the risk of dementia: the rotterdam study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Lower Counts of Astroglia and Activated Microglia in Patients with Alzheimer's Disease with Regular Use of Non-Steroidal Anti-Inflammatory Drugs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
1 September 2018
Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312283
retrieved
3 December 2018
NSAIDs and incident Alzheimer’s disease. the Rotterdam study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20205646
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
3D-Reconstruction of microglia and amyloid in APP23 transgenic mice: no evidence of intracellular amyloid
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20205646
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2174/187152710791011991
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PMCID
4312283
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed ID
20205646
1 reference
stated in
Europe PubMed Central
PMCID
4312283
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20205646%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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