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Notch signaling: switching an oncogene to a tumor suppressor.
scientific article published on 07 March 2014
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Europe PubMed Central
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3990910
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
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10 March 2020
review article
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title
Notch signaling: switching an oncogene to a tumor suppressor
(English)
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Europe PubMed Central
PMCID
3990910
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
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10 March 2020
author
Camille Lobry
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1
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Europe PubMed Central
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3990910
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10 March 2020
Marc Mansour
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3
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Europe PubMed Central
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3990910
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
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10 March 2020
Iannis Aifantis
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5
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Iannis Aifantis
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3990910
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10 March 2020
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Philmo Oh
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2
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
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10 March 2020
A Thomas Look
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4
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Europe PubMed Central
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3990910
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10 March 2020
language of work or name
English
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publication date
7 March 2014
1 reference
stated in
Europe PubMed Central
PMCID
3990910
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retrieved
10 March 2020
published in
Blood
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Europe PubMed Central
PMCID
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10 March 2020
volume
123
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10 March 2020
page(s)
2451-2459
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Europe PubMed Central
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10 March 2020
issue
16
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Europe PubMed Central
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10 March 2020
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NOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AML
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T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.
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Notch signaling in acute promyelocytic leukemia
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NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.
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Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma.
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The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development
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IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
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Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
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TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
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Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
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Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis
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A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development
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A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
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Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions
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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
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Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells
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Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
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Alterations of the Notch pathway in lung cancer.
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The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model
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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
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Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
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Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
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23 August 2017
Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells
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23 August 2017
Notch-dependent control of myelopoiesis is regulated by fucosylation
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23 August 2017
Of lineage and legacy: the development of mammalian hematopoietic stem cells
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23 August 2017
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.
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23 August 2017
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors
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23 August 2017
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
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23 August 2017
Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase
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23 August 2017
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
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23 August 2017
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
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23 August 2017
Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia
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23 August 2017
Notch signalling: a simple pathway becomes complex
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23 August 2017
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
1 reference
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PubMed Central
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23 August 2017
Ubiquitin ligases: cell-cycle control and cancer
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23 August 2017
Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.
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23 August 2017
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes
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23 August 2017
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability
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23 August 2017
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
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PubMed Central
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23 August 2017
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
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23 August 2017
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
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23 August 2017
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia
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23 August 2017
Notch regulation of lymphocyte development and function.
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23 August 2017
Osteoblastic cells regulate the haematopoietic stem cell niche
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23 August 2017
Glycosylation regulates Notch signalling.
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23 August 2017
The role of Notch in tumorigenesis: oncogene or tumour suppressor?
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23 August 2017
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation
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23 August 2017
Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development
1 reference
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PubMed Central
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23 August 2017
Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
Notch1 functions as a tumor suppressor in mouse skin
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
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23 August 2017
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Fringe is a glycosyltransferase that modifies Notch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Notch signalling via RBP-J promotes myeloid differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Inhibition of granulocytic differentiation by mNotch1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 August 2017
Notch activation inhibits AML growth and survival: a potential therapeutic approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
6 September 2017
Hematopoietic stem cells: to be or Notch to be.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
6 September 2017
Molecular genetics in acute myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
6 September 2017
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
6 September 2017
Suppression of erythroid but not megakaryocytic differentiation of human K562 erythroleukemic cells by notch-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
6 September 2017
GSK3beta is a negative regulator of the transcriptional coactivator MAML1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
14 September 2017
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
28 September 2017
Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
28 September 2017
The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 June 2018
Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
23 June 2018
Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Down-regulation of Notch-1 expression decreases PU.1-mediated myeloid differentiation signaling in acute myeloid leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Nicastrin functions as a gamma-secretase-substrate receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
The interplay between DSL proteins and ubiquitin ligases in Notch signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Notch signaling controls the generation and differentiation of early T lineage progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Gene expression profiling of pediatric acute myelogenous leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Regulation of notch signaling by o-linked fucose.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Notch1 expression in early lymphopoiesis influences B versus T lineage determination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Deficient T cell fate specification in mice with an induced inactivation of Notch1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3990910
retrieved
1 September 2018
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24608975
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
mNotch1 signaling and erythropoietin cooperate in erythroid differentiation of multipotent progenitor cells and upregulate beta-globin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24608975
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Defective Notch activation in microenvironment leads to myeloproliferative disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24608975
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24608975
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24608975
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/BLOOD-2013-08-355818
1 reference
stated in
Europe PubMed Central
PMCID
3990910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PMCID
3990910
1 reference
stated in
Europe PubMed Central
PMCID
3990910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PubMed ID
24608975
1 reference
stated in
Europe PubMed Central
PMCID
3990910
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608975%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
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