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The LIN28/let-7 Pathway in Cancer.
scientific article published on 28 March 2017
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Europe PubMed Central
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5368188
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
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17 March 2020
title
The LIN28/let-7 Pathway in Cancer
(English)
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stated in
Europe PubMed Central
PMC publication ID
5368188
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
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17 March 2020
author
John P. Hagan
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4
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Europe PubMed Central
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5368188
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
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17 March 2020
author name string
Julien Balzeau
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1
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Europe PubMed Central
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5368188
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
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17 March 2020
Miriam R Menezes
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2
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17 March 2020
Siyu Cao
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3
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Europe PubMed Central
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17 March 2020
publication date
28 March 2017
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Europe PubMed Central
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5368188
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retrieved
17 March 2020
published in
Frontiers in Genetics
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Europe PubMed Central
PMC publication ID
5368188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 March 2020
volume
8
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Europe PubMed Central
PMC publication ID
5368188
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17 March 2020
page(s)
31
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17 March 2020
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Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.
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23 August 2017
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23 August 2017
Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28
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23 August 2017
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Molecular basis for interaction of let-7 microRNAs with Lin28
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23 August 2017
The Lin28/let-7 axis regulates glucose metabolism
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23 August 2017
let-7 microRNAs induce tamoxifen sensitivity by downregulation of estrogen receptor α signaling in breast cancer.
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23 August 2017
Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
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23 August 2017
Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
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Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
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LIN28B promotes colon cancer progression and metastasis
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Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
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Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells
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Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells
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23 August 2017
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies
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23 August 2017
Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras
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23 August 2017
MicroRNAs in ovarian carcinomas
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23 August 2017
Direct cell reprogramming is a stochastic process amenable to acceleration
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23 August 2017
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
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23 August 2017
LIN28B confers radio-resistance through the posttranscriptional control of KRAS.
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23 August 2017
Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
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23 August 2017
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
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23 August 2017
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin28 promotes transformation and is associated with advanced human malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
The let-7 family of microRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Selective blockade of microRNA processing by Lin28
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
let-7 regulates self renewal and tumorigenicity of breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Induced pluripotent stem cell lines derived from human somatic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
MicroRNAs in carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Phase II study of a gemcitabine and cisplatin combination regimen in taxane resistant metastatic breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 August 2017
Lin28A and androgen receptor expression in ER-/Her2+ breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28 induces resistance to anti-androgens via promotion of AR splice variant generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Inhibition of c-Myc by let-7b mimic reverses mutidrug resistance in gastric cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
miRNA expression patterns in chemoresistant breast cancer tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28/let-7/Bcl-xL pathway: the underlying mechanism of drug resistance in Hep3B cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Let-7 g microRNA sensitizes fluorouracil-resistant human hepatoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Cancer stem cells: A contentious hypothesis now moving forward.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
PSP94 contributes to chemoresistance and its peptide derivative PCK3145 represses tumor growth in ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Mechanisms of Lin28-mediated miRNA and mRNA regulation--a structural and functional perspective
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
The Wnt-β-catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28a is a putative factor in regulating cancer stem cell-like properties in side population cells of oral squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28 regulates HER2 and promotes malignancy through multiple mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
6 September 2017
Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
14 September 2017
Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
14 September 2017
Influence of threonine metabolism on S-adenosylmethionine and histone methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
14 September 2017
The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
14 September 2017
Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
14 September 2017
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 June 2018
Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 June 2018
Positive expression of Lin28 is correlated with poor survival in gastric carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 June 2018
Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
23 June 2018
LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Discovery of a small-molecule inhibitor of protein-microRNA interaction using binding assay with a site-specifically labeled Lin28.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Lin28 promotes Her2 expression and Lin28/Her2 predicts poorer survival in gastric cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Functional study of risk loci of stem cell-associated gene lin-28B and associations with disease survival outcomes in epithelial ovarian cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
Metformin may antagonize Lin28 and/or Lin28B activity, thereby boosting let-7 levels and antagonizing cancer progression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368188
retrieved
1 September 2018
RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lin28: A microRNA regulator with a macro role
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunohistochemical expression of stem cell markers in pheochromocytomas/paragangliomas is associated with SDHx mutations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA-binding protein LIN28 is a marker for testicular germ cell tumors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28400788
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FGENE.2017.00031
1 reference
stated in
Europe PubMed Central
PMC publication ID
5368188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 March 2020
PMC publication ID
5368188
1 reference
stated in
Europe PubMed Central
PMC publication ID
5368188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 March 2020
PubMed publication ID
28400788
1 reference
stated in
Europe PubMed Central
PMC publication ID
5368188
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28400788%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 March 2020
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