(Q37724910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author

Athanasios Papakyriakou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Efstratios Stratikos

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

8

Marcin Drag

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

11

Dionisios Vourloumis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Efthalia Zervoudi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Dimitra Georgiadou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Irini Evnouchidou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Anna Gajda

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Marcin Poreba

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Guy S Salvesen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Akira Hattori

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Luc Swevers

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 April 2011

1 reference

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22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

435

1 reference

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22 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

411-420

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme

22 January 2020

cites work

1 reference

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Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1

23 August 2017

1 reference

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Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential

23 August 2017

1 reference

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Conformer generation with OMEGA: algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database

23 August 2017

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Aminopeptidase fingerprints, an integrated approach for identification of good substrates and optimal inhibitors

23 August 2017

1 reference

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The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum.

23 August 2017

1 reference

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IRAP identifies an endosomal compartment required for MHC class I cross-presentation

23 August 2017

1 reference

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

23 August 2017

1 reference

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The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Biochemical and enzymatic properties of the M1 family of aminopeptidases involved in the regulation of blood pressure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

The Amber biomolecular simulation programs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Cross-presentation: underlying mechanisms and role in immune surveillance

23 August 2017

1 reference

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The oxytocinase subfamily of M1 aminopeptidases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Electrostatics of nanosystems: application to microtubules and the ribosome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells

23 August 2017

1 reference

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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Degradation of cell proteins and the generation of MHC class I-presented peptides

23 August 2017

1 reference

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VMD: visual molecular dynamics

23 August 2017

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

23 August 2017

1 reference

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Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase

23 August 2017

1 reference

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Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic-reticulum aminopeptidase-1.

14 September 2017

1 reference

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Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Conversion of the substrate specificity of mouse proteinase granzyme B.

23 June 2018

1 reference

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In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000605

Converting trypsin to elastase: substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21314638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21314638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simulated interactions between angiotensin-converting enzyme and substrate gonadotropin-releasing hormone: novel insights into domain selectivity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21314638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20102049

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21314638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21314638

1 reference