(Q37725997)

22 August 2017

1 reference

title

Ambient tonicity and intestinal cytochrome CYP3A. (English)

1 reference

22 August 2017

Andrew I Chuang

1

1 reference

22 August 2017

Shinya Ito

series ordinal

2

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22 August 2017

language of work or name

English

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publication date

1 August 2010

1 reference

Expert Opinion on Drug Metabolism & Toxicology

22 August 2017

published in

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22 August 2017

volume

6

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22 August 2017

issue

8

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22 August 2017

page(s)

883-893

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Substrate binding to cytochromes P450.

22 August 2017

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21 January 2018

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Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43.

21 January 2018

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Species differences in in vitro and in vivo small intestinal metabolism of CYP3A substrates

21 January 2018

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21 January 2018

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Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

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Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues

21 January 2018

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PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity

21 January 2018

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Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

21 January 2018

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Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 January 2018

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21 January 2018

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Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals

21 January 2018

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The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

21 January 2018

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Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells

21 January 2018

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Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway

21 January 2018

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Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4alpha: evidence for direct regulation in the intestine

21 January 2018

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21 January 2018

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Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

21 January 2018

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Discovery of osmosensitive transcriptional regulation of human cytochrome P450 3As by the tonicity-responsive enhancer binding protein (nuclear factor of activated T cells 5).

21 January 2018

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NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

21 January 2018

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Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells

21 January 2018

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Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo

21 January 2018

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Cell cycle delay and apoptosis in response to osmotic stress.

21 January 2018

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Hypertonic shock inhibits growth factor receptor signaling, induces caspase-3 activation, and causes reversible fragmentation of the mitochondrial network.

21 January 2018

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Osmotic stress-induced remodeling of the cortical cytoskeleton

21 January 2018

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Phosphorylation of eukaryotic initiation factor (eIF) 4E is not required for de novo protein synthesis following recovery from hypertonic stress in human kidney cells

21 January 2018

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High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNA

21 January 2018

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21 January 2018

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Intracellular water homeostasis and the mammalian cellular osmotic stress response

21 January 2018

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A molecular mechanism for osmolyte-induced protein stability

21 January 2018

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Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene

21 January 2018

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Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region

21 January 2018

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Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress

21 January 2018

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Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

21 January 2018

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Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)

21 January 2018

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cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein

21 January 2018

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ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

21 January 2018

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Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5.

21 January 2018

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Mouse TonEBP-NFAT5: expression in early development and alternative splicing

21 January 2018

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21 January 2018

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Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes

21 January 2018

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NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells

21 January 2018

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Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice.

21 January 2018

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Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5.

21 January 2018

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Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations

21 January 2018

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21 January 2018

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Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies.

21 January 2018

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Characterization of fluids from the stomach and proximal jejunum in men and women.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003781912

Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003781912

Comparative study of the effect of luminal hypotonicity on mucosal permeability in rat upper gastrointestinal tract

21 January 2018

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Inhibition of thirst when dehydrated rats drink water or saline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003781912

The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003781912

Thermogenesis induced by osmotic stimulation of the intestines in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003781912

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

21 January 2018

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Defining relationships between the known members of the cytochrome P450 3A subfamily, including five putative chimpanzee members.

21 January 2018

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Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

21 January 2018

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Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

21 January 2018

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Effect of sodium alterations on hepatic cytochrome P450 3A2 and 2C11 and renal function in rats

21 January 2018

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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Aldosterone in salt-sensitive hypertension and metabolic syndrome.

21 January 2018

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Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement

21 January 2018

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Renal corticosterone 6 beta-hydroxylase in the spontaneously hypertensive rat.

21 January 2018

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Cardiovascular consequences of cortisol excess

21 January 2018

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Urinary 6?-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals

21 January 2018

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CYP3A variation and the evolution of salt-sensitivity variants

21 January 2018

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CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults

21 January 2018

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Sequence diversity and haplotype structure at the human CYP3A cluster

21 January 2018

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Association of CYP3A5 genotypes with blood pressure and renal function in African families

21 January 2018

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Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice.

21 January 2018

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Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells

21 January 2018

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10.1517/17425251003781912

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference