(Q37726449)

22 August 2017

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title

MicroRNA-mediated gene silencing (English)

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22 August 2017

0 references

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Cara T Pager

1

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22 August 2017

Karen A Wehner

series ordinal

2

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22 August 2017

Gabriele Fuchs

series ordinal

3

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22 August 2017

Peter Sarnow

series ordinal

4

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22 August 2017

publication date

27 October 2009

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Progress in Molecular Biology and Translational Science

22 August 2017

published in

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22 August 2017

volume

90

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22 August 2017

page(s)

187-210

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MicroRNA functions in animal development and human disease

22 August 2017

cites work

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7 January 2021

Phylogenetic shadowing and computational identification of human microRNA genes

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7 January 2021

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

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7 January 2021

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

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7 January 2021

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells

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7 January 2021

Mutations that lead to reiterations in the cell lineages of C. elegans

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7 January 2021

Heterochronic mutants of the nematode Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification of novel genes coding for small expressed RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

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https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

An extensive class of small RNAs in Caenorhabditis elegans

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7 January 2021

The microRNA Registry

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification of virus-encoded microRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification of microRNAs of the herpesvirus family

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification and characterization of human cytomegalovirus-encoded microRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNAs: expression, avoidance and subversion by vertebrate viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification of mammalian microRNA host genes and transcription units

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNA biogenesis: coordinated cropping and dicing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The Microprocessor complex mediates the genesis of microRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The Drosha-DGCR8 complex in primary microRNA processing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The nuclear RNase III Drosha initiates microRNA processing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Human let-7 stem-loop precursors harbor features of RNase III cleavage products

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Thirty-three years later, a glimpse at the ribonuclease III active site.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Nuclear export of microRNA precursors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Identification of eight members of the Argonaute family in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Argonaute2 is the catalytic engine of mammalian RNAi

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Purified Argonaute2 and an siRNA form recombinant human RISC

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Getting to the root of miRNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Argonaute proteins: mediators of RNA silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Integration of microRNA miR-122 in hepatic circadian gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Temporal pattern formation by heterochronic genes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Involvement of microRNA in AU-rich element-mediated mRNA instability

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Specificity of microRNA target selection in translational repression

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

siRNAs can function as miRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNAs direct rapid deadenylation of mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Deadenylation is a widespread effect of miRNA regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Inhibition of translational initiation by Let-7 MicroRNA in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Disruption of GW bodies impairs mammalian RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Internal ribosome entry sites in eukaryotic mRNA molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Short RNAs repress translation after initiation in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Human let-7a miRNA blocks protein production on actively translating polyribosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Recapitulation of short RNA-directed translational gene silencing in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Cell-cell contact globally activates microRNA biogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Switching from repression to activation: microRNAs can up-regulate translation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Processing bodies require RNA for assembly and contain nontranslating mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

A role for the P-body component GW182 in microRNA function

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

miRNA in situ hybridization in formaldehyde and EDC-fixed tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Cellular cofactors affecting hepatitis C virus infection and replication

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

microRNA-122 stimulates translation of hepatitis C virus RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Interferon modulation of cellular microRNAs as an antiviral mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Gene silencing using micro-RNA designed hairpins

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Helper-dependent adenovirus-mediated short hairpin RNA expression in the liver activates the interferon response

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

The first analogues of LNA (Locked Nucleic Acids): Phosphorothioate-LNA and 2′-thio-LNA

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Synthesis of Novel Bicyclo[2.2.1] Ribonucleosides: 2'-Amino- and 2'-Thio-LNA Monomeric Nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Antisense properties of duplex- and triplex-forming PNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

LNA-mediated microRNA silencing in non-human primates

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Silencing of microRNAs in vivo with 'antagomirs'

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

RNA interference in mammalian cells by chemically-modified RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Mechanism of action of interferon and ribavirin in treatment of hepatitis C

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2809%2990005-9

7 January 2021

10.1016/S1877-1173(09)90005-9

Identifiers

DOI

1 reference

22 August 2017

1 reference