(Q37760665)

22 August 2017

1 reference

title

The multiple faces of CXCL12 (SDF-1alpha) in the regulation of immunity during health and disease (English)

1 reference

22 August 2017

Nathan Karin

1

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22 August 2017

publication date

25 May 2010

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Journal of Leukocyte Biology

22 August 2017

published in

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22 August 2017

volume

88

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22 August 2017

issue

3

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22 August 2017

page(s)

463-473

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Chemokines: a new classification system and their role in immunity

22 August 2017

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21 January 2018

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Selective autoantibody production against CCL3 is associated with human type 1 diabetes mellitus and serves as a novel biomarker for its diagnosis

21 January 2018

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Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

21 January 2018

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C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis

21 January 2018

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Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis.

21 January 2018

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CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

21 January 2018

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Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice

21 January 2018

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Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

21 January 2018

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Regulation of neutrophil homeostasis

21 January 2018

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CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions

21 January 2018

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Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

The biology of chemokines and their receptors

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

A controlled trial of natalizumab for relapsing multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Cancer and the chemokine network

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Chemokines: agents for the immunotherapy of cancer?

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

CCL2 is a potent regulator of prostate cancer cell migration and proliferation

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Distinct role of macrophages in different tumor microenvironments

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The role of CXC chemokines and their receptors in cancer.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0909602

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion

21 January 2018

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Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy

21 January 2018

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Cytokine profiling of prostatic fluid from cancerous prostate glands identifies cytokines associated with extent of tumor and inflammation.

21 January 2018

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CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration

21 January 2018

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

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The origin and function of tumor-associated macrophages

21 January 2018

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Critical roles of CXC chemokine ligand 16/scavenger receptor that binds phosphatidylserine and oxidized lipoprotein in the pathogenesis of both acute and adoptive transfer experimental autoimmune encephalomyelitis

21 January 2018

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Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines

21 January 2018

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Monocyte chemotactic protein 1 regulates oral tolerance induction by inhibition of T helper cell 1-related cytokines

21 January 2018

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CXCR4-CCR5: a couple modulating T cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Prevention of murine experimental autoimmune encephalomyelitis by in vivo expression of a novel recombinant immunotoxin DT390-RANTES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CD4+ T-cell subsets in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Functional diversity of helper T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Interleukin-12 and its role in the generation of TH1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Role of cytokines in determining T-lymphocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A proinflammatory role for IL-18 in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

T(H)-17 cells in the circle of immunity and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Cytokines in the induction and resolution of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Control of regulatory T cell lineage commitment and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

T(H)1 cells control themselves by producing interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Mechanisms of foxp3+ T regulatory cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Tr1 cell-dependent active tolerance blunts the pathogenic effects of determinant spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Transcriptional regulation of Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The production of IL-10 by human regulatory T cells is enhanced by IL-2 through a STAT5-responsive intronic enhancer in the IL-10 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Suppression of ongoing experimental autoimmune encephalomyelitis by neutralizing the function of the p28 subunit of IL-27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Further checkpoints in Th1 development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CCR8 expression identifies CD4 memory T cells enriched for FOXP3+ regulatory and Th2 effector lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Molecular cloning and structure of a pre-B-cell growth-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Chemokines and the arrest of lymphocytes rolling under flow conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The chemokine stromal cell-derived factor-1 alpha modulates alpha 4 beta 7 integrin-mediated lymphocyte adhesion to mucosal addressin cell adhesion molecule-1 and fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis: regulation of CXCL12 expression in astrocytes by soluble myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3-/- mice with experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Involvement of chemokine receptors in breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

The Yin and Yang of CD4(+) regulatory T cells in autoimmunity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Yin-Yang of costimulation: crucial controls of immune tolerance and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Chemokine expression in murine experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

α4Integrins as Therapeutic Targets in Autoimmune Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

Tumor promotion by tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0909602

21 January 2018

Identifiers

DOI

10.1189/JLB.0909602

1 reference

22 August 2017

1 reference