(Q37760846)

22 August 2017

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title

"Without Ub I am nothing": NEMO as a multifunctional player in ubiquitin-mediated control of NF-kappaB activation (English)

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22 August 2017

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Jérémie Gautheron

1

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PubMed ID

20502939

22 August 2017

Gilles Courtois

series ordinal

2

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22 August 2017

26 May 2010

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Cellular and Molecular Life Sciences

22 August 2017

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22 August 2017

67

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22 August 2017

18

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22 August 2017

3101-3113

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0404-9

22 August 2017

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cites work

Post-translational modifications and their biological functions: proteomic analysis and systematic approaches

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0404-9

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0404-9

Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0404-9

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0404-9

Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin

21 January 2018

1 reference

12 December 2020

Structural Basis for Recognition of Diubiquitins by NEMO

1 reference

12 December 2020

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

1 reference

12 December 2020

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

1 reference

12 December 2020

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

1 reference

12 December 2020

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

1 reference

12 December 2020

Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

1 reference

12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

12 December 2020

Principles of ubiquitin and SUMO modifications in DNA repair.

1 reference

12 December 2020

1 reference

12 December 2020

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

1 reference

12 December 2020

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

12 December 2020

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

1 reference

12 December 2020

Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

12 December 2020

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

1 reference

12 December 2020

Many faces of NF-kappaB signaling induced by genotoxic stress

1 reference

12 December 2020

Intracellular NOD-like receptors in host defense and disease

1 reference

12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

12 December 2020

The emerging complexity of protein ubiquitination

1 reference

12 December 2020

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

1 reference

12 December 2020

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation

1 reference

12 December 2020

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

1 reference

12 December 2020

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

1 reference

12 December 2020

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding

1 reference

12 December 2020

The zinc finger of NEMO is a functional ubiquitin-binding domain

1 reference

12 December 2020

Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80.

1 reference

12 December 2020

Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin

1 reference

12 December 2020

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

12 December 2020

Ubiquitin: structures, functions, mechanisms

1 reference

12 December 2020

Nonproteolytic functions of ubiquitin in cell signaling

1 reference

12 December 2020

NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation

1 reference

12 December 2020

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

1 reference

12 December 2020

Specificity of the interaction between ubiquitin-associated domains and ubiquitin

1 reference

12 December 2020

Manipulation of host-cell pathways by bacterial pathogens

1 reference

12 December 2020

NF-kappaB-related genetic diseases

1 reference

12 December 2020

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

1 reference

12 December 2020

Type III secretion systems shape up as they ship out.

1 reference

12 December 2020

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

1 reference

12 December 2020

Multitasking with ubiquitin through multivalent interactions

1 reference

12 December 2020

Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome

1 reference

12 December 2020

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

1 reference

12 December 2020

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

1 reference

12 December 2020

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

12 December 2020

Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling

1 reference

12 December 2020

Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.

1 reference

12 December 2020

A ubiquitin ligase complex assembles linear polyubiquitin chains

1 reference

12 December 2020

Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase

1 reference

12 December 2020

Charging it up: global analysis of protein phosphorylation

1 reference

12 December 2020

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

1 reference

12 December 2020

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

12 December 2020

Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation.

1 reference

12 December 2020

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

1 reference

12 December 2020

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

1 reference

12 December 2020

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

12 December 2020

Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.

1 reference

12 December 2020

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

12 December 2020

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

12 December 2020

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

1 reference

12 December 2020

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

1 reference

12 December 2020

The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins

1 reference

12 December 2020

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

1 reference

12 December 2020

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

12 December 2020

Type III secretion effectors of the IpaH family are E3 ubiquitin ligases.

1 reference

12 December 2020

A genomic and functional inventory of deubiquitinating enzymes

1 reference

12 December 2020

Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions

1 reference

12 December 2020

Shared principles in NF-kappaB signaling

1 reference

12 December 2020

Signaling to NF-kappaB

1 reference

12 December 2020

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

1 reference

12 December 2020

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

12 December 2020

10.1007/S00018-010-0404-9

Identifiers

DOI

1 reference

release_ljjpl6znnjebhn5l46crv53d2i

22 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ljjpl6znnjebhn5l46crv53d2i

24 November 2022

mapped directly with Wikidata item

PubMed ID

20502939

1 reference

PubMed ID

20502939