(Q37579634)

21 August 2017

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title

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs (English)

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21 August 2017

J Silke

1

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author name string

R Brink

series ordinal

2

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21 August 2017

language of work or name

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1 January 2010

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Cell Death & Differentiation

21 August 2017

published in

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21 August 2017

volume

17

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21 August 2017

issue

1

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21 August 2017

page(s)

35-45

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TRAF6-deficient mice display hypohidrotic ectodermal dysplasia

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

IAPs, RINGs and ubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Crosstalk via the NF-kappaB signaling system

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Roles of TRAF molecules in B lymphocyte function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Shaping the nuclear action of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

CD40 regulates the processing of NF-kappaB2 p100 to p52

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

A fourth IkappaB protein within the NF-kappaB signaling module

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Circuitry of nuclear factor kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Mechanism of I kappa B alpha binding to NF-kappa B dimers

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Structural Basis for Recognition of Diubiquitins by NEMO

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The multifaceted roles of TRAFs in the regulation of B-cell function.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The structural basis for the recognition of diverse receptor sequences by TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Two distinct signalling cascades target the NF-kappaB regulatory factor c-IAP1 for degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Ubiquitin and endocytic protein sorting

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TWEAK shall inherit the earth

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor kappaB2 in regulating circulating B cell numbers

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

A ubiquitin ligase complex assembles linear polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The host defense of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.114

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.114

1 reference

Dimensions Publication ID

21 August 2017

1040788878

0 references

1 reference