(Q37763095)

22 August 2017

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title

Salirasib in the treatment of pancreatic cancer (English)

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22 August 2017

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2

Razelle Kurzrock

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Apostolia Maria Tsimberidou

22 August 2017

series ordinal

3

object named as

Apostolia-Maria Tsimberidou

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22 August 2017

author name string

Ernesto Bustinza-Linares

series ordinal

1

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22 August 2017

language of work or name

English

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publication date

1 June 2010

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22 August 2017

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22 August 2017

volume

6

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22 August 2017

issue

6

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22 August 2017

page(s)

885-891

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Estimates of the cancer incidence and mortality in Europe in 2006.

22 August 2017

cites work

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Carcinoma of the pancreas and papilla of Vater: presenting symptoms, signs, and diagnosis related to stage and tumour site. A prospective multicentre trial in 472 patients. Norwegian Pancreatic Cancer Trial

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Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses

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AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE.

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21 January 2018

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

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Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

21 January 2018

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RAS inhibitors: potential for cancer therapeutics

21 January 2018

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Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer

21 January 2018

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Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

21 January 2018

1 reference

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

1 reference

Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

21 January 2018

1 reference

Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

21 January 2018

1 reference

The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer

21 January 2018

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Subcellular localization determines MAP kinase signal output.

21 January 2018

1 reference

Ras plasma membrane signalling platforms

21 January 2018

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Direct visualization of Ras proteins in spatially distinct cell surface microdomains

21 January 2018

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Compartmentalized signalling of Ras.

21 January 2018

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Ras proteins: different signals from different locations

21 January 2018

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Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice

21 January 2018

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Dislodgment and accelerated degradation of Ras.

21 January 2018

1 reference

Novel Ras antagonist blocks human melanoma growth

21 January 2018

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Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid

21 January 2018

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Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth

21 January 2018

1 reference

Prenyl-binding domains: potential targets for Ras inhibitors and anti-cancer drugs

21 January 2018

1 reference

Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies.

21 January 2018

1 reference

Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).

21 January 2018

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Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells

21 January 2018

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Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells

21 January 2018

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The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.

21 January 2018

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Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo

21 January 2018

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Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells

21 January 2018

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Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells

21 January 2018

1 reference

Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors.

21 January 2018

1 reference

Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia

21 January 2018

1 reference

A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FON.10.71

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22 August 2017

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