(Q37767611)

22 August 2017

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title

Mitochondrial dynamics in cell death and neurodegeneration (English)

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22 August 2017

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Dong-Hyung Cho

1

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22 August 2017

Tomohiro Nakamura

series ordinal

2

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22 August 2017

Stuart A Lipton

series ordinal

3

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22 August 2017

publication date

25 June 2010

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Cellular and Molecular Life Sciences

22 August 2017

published in

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22 August 2017

volume

67

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22 August 2017

issue

20

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22 August 2017

page(s)

3435-3447

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Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p

22 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Mammalian dynamin-like protein DLP1 tubulates membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Abnormal mitochondrial dynamics and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Dynamin GTPase domain mutants block endocytic vesicle formation at morphologically distinct stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Lipid signaling on the mitochondrial surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0435-2

Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy

21 January 2018

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12 December 2020

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

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12 December 2020

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

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12 December 2020

A lethal defect of mitochondrial and peroxisomal fission

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12 December 2020

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

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12 December 2020

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

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12 December 2020

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

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12 December 2020

The PINK1/Parkin pathway regulates mitochondrial morphology

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12 December 2020

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

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12 December 2020

Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease).

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12 December 2020

Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta

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12 December 2020

High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy

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12 December 2020

Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drpl and hFis1

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12 December 2020

Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons

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12 December 2020

Three-dimensional reconstruction of dynamin in the constricted state

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12 December 2020

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

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12 December 2020

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

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12 December 2020

Mitochondrial structural and functional dynamics in Huntington's disease

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12 December 2020

Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations

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12 December 2020

Novel pharmacological targets for the treatment of Parkinson's disease

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12 December 2020

Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons

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12 December 2020

Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2

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12 December 2020

Endophilin B1 is required for the maintenance of mitochondrial morphology

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12 December 2020

Mitochondrial NAD+-linked State 3 respiration and complex-I activity are compromised in the cerebral cortex of 3-nitropropionic acid-induced rat model of Huntington's disease.

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12 December 2020

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

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12 December 2020

A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics

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12 December 2020

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

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12 December 2020

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

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12 December 2020

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

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12 December 2020

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

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12 December 2020

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

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12 December 2020

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

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12 December 2020

Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis

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12 December 2020

Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization

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12 December 2020

Get the balance right: mitofusins roles in health and disease

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12 December 2020

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

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12 December 2020

The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division

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12 December 2020

hFis1, a novel component of the mammalian mitochondrial fission machinery

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12 December 2020

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

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12 December 2020

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

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12 December 2020

Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

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12 December 2020

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

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12 December 2020

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury

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12 December 2020

The gene encoding ganglioside-induced differentiation-associated protein 1 is mutated in axonal Charcot-Marie-Tooth type 4A disease

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12 December 2020

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

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12 December 2020

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

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12 December 2020

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

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12 December 2020

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

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12 December 2020

Dnm1 forms spirals that are structurally tailored to fit mitochondria

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12 December 2020

Role of Bax and Bak in mitochondrial morphogenesis

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12 December 2020

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

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12 December 2020

Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release

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12 December 2020

Identification of a novel protein that regulates mitochondrial fusion by modulating mitofusin (Mfn) protein function

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12 December 2020

CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology

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12 December 2020

Identification of novel proteins associated with both alpha-synuclein and DJ-1

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12 December 2020

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

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12 December 2020

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

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12 December 2020

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

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12 December 2020

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

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12 December 2020

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

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12 December 2020

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

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12 December 2020

Mitochondrial fission in apoptosis, neurodegeneration and aging

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12 December 2020

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

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12 December 2020

Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo

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12 December 2020

Clinical and electrophysiologic features of CMT2A with mutations in the mitofusin 2 gene

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12 December 2020

Intracellular amyloid-beta in Alzheimer's disease

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12 December 2020

Cytochrome c: functions beyond respiration

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12 December 2020

Mitochondrial membrane remodelling regulated by a conserved rhomboid protease

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12 December 2020

The SUMO protease SENP5 is required to maintain mitochondrial morphology and function

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12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

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12 December 2020

SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle

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12 December 2020

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

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12 December 2020

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

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12 December 2020

The dynamin superfamily: universal membrane tubulation and fission molecules?

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12 December 2020

A human dynamin-related protein controls the distribution of mitochondria

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12 December 2020

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

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12 December 2020

Dynamin-like protein 1 is involved in peroxisomal fission

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12 December 2020

Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

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12 December 2020

OPA1 requires mitofusin 1 to promote mitochondrial fusion

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12 December 2020

Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.

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12 December 2020

The molecular mechanism of mitochondrial fusion

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12 December 2020

Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease

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12 December 2020

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

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12 December 2020

Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis

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12 December 2020

Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis

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12 December 2020

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

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12 December 2020

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

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12 December 2020

Targeting and function of the mitochondrial fission factor GDAP1 are dependent on its tail-anchor

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12 December 2020

Mitochondrial morphogenesis, dendrite development, and synapse formation in cerebellum require both Bcl-w and the glutamate receptor delta2

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12 December 2020

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

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12 December 2020

Structural basis of mitochondrial tethering by mitofusin complexes.

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12 December 2020

Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis

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12 December 2020

Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion

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12 December 2020

MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology

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12 December 2020

Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A

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12 December 2020

Mitochondrial fusion and fission in mammals

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12 December 2020

Amyloid-beta-induced mitochondrial dysfunction

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12 December 2020

Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death

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12 December 2020

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

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12 December 2020

The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis

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12 December 2020

eOPA1: an online database for OPA1 mutations

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12 December 2020

The dynamin middle domain is critical for tetramerization and higher-order self-assembly

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12 December 2020

The mitochondrial spiral. An adequate cause of dementia in the Alzheimer's syndrome.

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12 December 2020

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

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12 December 2020

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

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12 December 2020

Ugo1p is a multipass transmembrane protein with a single carrier domain required for mitochondrial fusion

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12 December 2020

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

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12 December 2020

Mitochondrial dynamics and disease, OPA1

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12 December 2020

6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.

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12 December 2020

SLP-2 is required for stress-induced mitochondrial hyperfusion

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12 December 2020

Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

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12 December 2020

OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis

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12 December 2020

Huntingtin aggregation and toxicity in Huntington's disease

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12 December 2020

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

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12 December 2020

Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway.

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12 December 2020

Mitochondrial dynamics and apoptosis

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12 December 2020

Autophagy fights disease through cellular self-digestion

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12 December 2020

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

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12 December 2020

Mitochondria: dynamic organelles in disease, aging, and development

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12 December 2020

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

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12 December 2020

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

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12 December 2020

Mitochondrial fragmentation in neurodegeneration

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12 December 2020

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

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12 December 2020

OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria

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12 December 2020

Control of mitochondrial morphology by a human mitofusin

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12 December 2020

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

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12 December 2020

Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21

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12 December 2020

Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.

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12 December 2020

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

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12 December 2020

The Carboxy-Terminal Modulator Protein (CTMP) regulates mitochondrial dynamics

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12 December 2020

Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis

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12 December 2020

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

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12 December 2020

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

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12 December 2020

Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

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12 December 2020

Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance

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12 December 2020

Autophagy in the Pathogenesis of Disease

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12 December 2020

Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax

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12 December 2020

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

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12 December 2020

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

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12 December 2020

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

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12 December 2020

Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.

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12 December 2020

Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.

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12 December 2020

Mitochondria-specific function of the dynamin family protein DLP1 is mediated by its C-terminal domains

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12 December 2020

The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

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12 December 2020

Mitochondrial dynamics in mammalian health and disease

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12 December 2020

Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations

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12 December 2020

Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A.

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12 December 2020

BAR domains as sensors of membrane curvature: the amphiphysin BAR structure

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12 December 2020

The mitochondrion in apoptosis: how Pandora's box opens

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12 December 2020

A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice

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12 December 2020

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

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12 December 2020

Effects of overexpression of huntingtin proteins on mitochondrial integrity

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12 December 2020

Mechanistic analysis of a dynamin effector

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12 December 2020

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

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12 December 2020

10.1007/S00018-010-0435-2

Identifiers

DOI

1 reference

release_6ohnhymdzrflpl52r2k7jdtkmu

22 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6ohnhymdzrflpl52r2k7jdtkmu

24 November 2022

mapped directly with Wikidata item

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