(Q37768449)

22 August 2017

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title

Antioxidant approaches for the treatment of Alzheimer's disease (English)

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22 August 2017

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8

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22 August 2017

2

Xiongwei Zhu

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22 August 2017

6

Mark A Smith

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22 August 2017

3

Gemma Casadesus

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22 August 2017

1

Hyun Pil Lee

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22 August 2017

7

Hyoung-gon Lee

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22 August 2017

Rudy J Castellani

4

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PubMed ID

20586698

22 August 2017

Akihiko Nunomura

series ordinal

5

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PubMed ID

20586698

22 August 2017

language of work or name

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1 July 2010

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

22 August 2017

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22 August 2017

10

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22 August 2017

1201-1208

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22 August 2017

7

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22 August 2017

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Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain

21 January 2018

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Tau phosphorylation in Alzheimer's disease: pathogen or protector?

21 January 2018

1 reference

Amyloid beta: the alternate hypothesis

21 January 2018

1 reference

APOE genotype effects on Alzheimer's disease onset and epidemiology

21 January 2018

1 reference

ApoE-dependent plasticity in Alzheimer's disease.

21 January 2018

1 reference

Alzheimer's disease: genotypes, phenotypes, and treatments

21 January 2018

1 reference

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

21 January 2018

1 reference

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

21 January 2018

1 reference

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

Radical AGEing in Alzheimer's disease

21 January 2018

1 reference

Glutathione, oxidative stress and neurodegeneration

21 January 2018

1 reference

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

21 January 2018

1 reference

Pathways towards and away from Alzheimer's disease

21 January 2018

1 reference

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

1 reference

Role of mitochondrial dysfunction in Alzheimer's disease

21 January 2018

1 reference

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

21 January 2018

1 reference

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

21 January 2018

1 reference

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

21 January 2018

1 reference

Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease.

21 January 2018

1 reference

Autophagocytosis of mitochondria is prominent in Alzheimer disease.

21 January 2018

1 reference

Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation.

21 January 2018

1 reference

Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias.

21 January 2018

1 reference

Promotion of transition metal-induced reactive oxygen species formation by beta-amyloid

21 January 2018

1 reference

Alzheimer disease, the two-hit hypothesis: an update

21 January 2018

1 reference

Alzheimer's disease: the two-hit hypothesis

21 January 2018

1 reference

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.

21 January 2018

1 reference

The cholinergic system in Alzheimer's disease

21 January 2018

1 reference

Presynaptic cholinergic dysfunction in patients with dementia.

21 January 2018

1 reference

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

21 January 2018

1 reference

Do cholinesterase inhibitors have disease-modifying effects in Alzheimer's disease?

21 January 2018

1 reference

Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

21 January 2018

1 reference

Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine

21 January 2018

1 reference

Infusion of (+) -MK-801 and memantine -- contrasting effects on radial maze learning in rats with entorhinal cortex lesion.

21 January 2018

1 reference

Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide, and vitamin E.

21 January 2018

1 reference

Oxidative damage in neurodegenerative disease

21 January 2018

1 reference

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

21 January 2018

1 reference

Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study

21 January 2018

1 reference

Dietary intake of antioxidants and risk of Alzheimer disease

21 January 2018

1 reference

Antioxidant vitamin supplement use and risk of dementia or Alzheimer's disease in older adults

21 January 2018

1 reference

Vitamin E and donepezil for the treatment of mild cognitive impairment

21 January 2018

1 reference

Ginkgo biloba for prevention of dementia: a randomized controlled trial

21 January 2018

1 reference

Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics

21 January 2018

1 reference

Targeting antioxidants to mitochondria: a new therapeutic direction

21 January 2018

1 reference

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

21 January 2018

1 reference

Mitochondrial targeting of quinones: therapeutic implications.

21 January 2018

1 reference

Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

21 January 2018

1 reference

Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

21 January 2018

1 reference

Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.

21 January 2018

1 reference

Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

21 January 2018

1 reference

Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide

21 January 2018

1 reference

Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron

21 January 2018

1 reference

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

Intramuscular desferrioxamine in patients with Alzheimer's disease

21 January 2018

1 reference

Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance.

21 January 2018

1 reference

Nanoparticle and iron chelators as a potential novel Alzheimer therapy

21 January 2018

1 reference

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

21 January 2018

1 reference

Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons

21 January 2018

1 reference

Mitochondria as a target for neurotoxins and neuroprotective agents

21 January 2018

1 reference

Efficacy of a vitamin/nutriceutical formulation for early-stage Alzheimer's disease: a 1-year, open-label pilot study with an 16-month caregiver extension

21 January 2018

1 reference

Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease

21 January 2018

1 reference

Reactive oxygen species in vascular biology: implications in hypertension

21 January 2018

1 reference

Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications

21 January 2018

1 reference

Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats

21 January 2018

1 reference

Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertension

21 January 2018

1 reference

Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?

21 January 2018

1 reference

Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

21 January 2018

1 reference

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

21 January 2018

1 reference

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

21 January 2018

1 reference

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERN.10.74

1 reference

22 August 2017

1 reference

PubMed ID

20586698