(Q37773243)

22 August 2017

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title

Kinoids: a family of immunogens for active anticytokine immunotherapy applied to autoimmune diseases and cancer (English)

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22 August 2017

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5

Arsène Burny

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Daniel Zagury

3

object named as

Daniel Zagury

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author name string

Bernard Bizzini

1

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22 August 2017

Béatrice Drouet

2

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22 August 2017

Daniel Zagury

3

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22 August 2017

Marc Abitbol

4

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22 August 2017

Marie-Christophe Boissier

6

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22 August 2017

publication date

1 May 2010

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22 August 2017

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22 August 2017

volume

2

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22 August 2017

issue

3

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22 August 2017

page(s)

347-365

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Interleukin-12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells

22 August 2017

cites work

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IL-23 promotes tumour incidence and growth

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IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

21 January 2018

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Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

21 January 2018

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An endotoxin-induced serum factor that causes necrosis of tumors

21 January 2018

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Dendritic cells and cytokines in human inflammatory and autoimmune diseases

21 January 2018

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Toward a new generation of vaccines: the anti-cytokine therapeutic vaccines

21 January 2018

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Chemokine-chemokine receptors in cancer immunotherapy

21 January 2018

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The role of TNF superfamily members in T-cell function and diseases

21 January 2018

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Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4.

21 January 2018

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

21 January 2018

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

21 January 2018

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Type 17 T helper cells-origins, features and possible roles in rheumatic disease

21 January 2018

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Emerging applications of anticytokine vaccines

21 January 2018

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21 January 2018

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LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

21 January 2018

1 reference

Novel IL-12 family members shed light on the orchestration of Th1 responses

21 January 2018

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Mucosal cytokine network in inflammatory bowel disease

21 January 2018

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TNF-blocking therapies: an alternative mode of action?

21 January 2018

1 reference

Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

21 January 2018

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Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study

21 January 2018

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A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

21 January 2018

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21 January 2018

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Systemic lupus erythematosus.

21 January 2018

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The type I interferon system in systemic lupus erythematosus

21 January 2018

1 reference

Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases

21 January 2018

1 reference

Systemic lupus erythematosus: all roads lead to type I interferons

21 January 2018

1 reference

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

21 January 2018

1 reference

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

21 January 2018

1 reference

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study

21 January 2018

1 reference

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

21 January 2018

1 reference

Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus.

21 January 2018

1 reference

Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies

21 January 2018

1 reference

Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120

21 January 2018

1 reference

Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.

21 January 2018

1 reference

Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1.

21 January 2018

1 reference

Apoptosis as an HIV strategy to escape immune attack

21 January 2018

1 reference

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

21 January 2018

1 reference

Interferons in the persistence, pathogenesis, and treatment of HIV infection

21 January 2018

1 reference

Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway

21 January 2018

1 reference

Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection

21 January 2018

1 reference

The tumor microenvironment and its role in promoting tumor growth

21 January 2018

1 reference

Tumor angiogenesis: therapeutic implications

21 January 2018

1 reference

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

21 January 2018

1 reference

Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression

21 January 2018

1 reference

Interleukin-6 and prostate cancer progression

21 January 2018

1 reference

Tumour escape from immune surveillance through dendritic cell inactivation

21 January 2018

1 reference

Anti-angiogenic therapy of exudative age-related macular degeneration: current progress and emerging concepts

21 January 2018

1 reference

Bevacizumab: direct anti-VEGF therapy in renal cell carcinoma

21 January 2018

1 reference

Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration

21 January 2018

1 reference

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

21 January 2018

1 reference

IL-4: a key cytokine in atopy

21 January 2018

1 reference

The role of IL-13 and its receptor in allergy and inflammatory responses

21 January 2018

1 reference

Atopy and asthma: genetic variants of IL-4 and IL-13 signalling

21 January 2018

1 reference

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

21 January 2018

1 reference

Individual medicine in inflammatory bowel disease: monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies

21 January 2018

1 reference

Keyhole limpet hemocyanin (KLH): a biomedical review

21 January 2018

1 reference

Active anti-interferon-alpha immunization: a European-Israeli, randomized, double-blind, placebo-controlled clinical trial in 242 HIV-1--infected patients (the EURIS study).

21 January 2018

1 reference

TNFalpha kinoid vaccination-induced neutralizing antibodies to TNFalpha protect mice from autologous TNFalpha-driven chronic and acute inflammation

21 January 2018

1 reference

VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases

21 January 2018

1 reference

IFNalpha kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model

21 January 2018

1 reference

The perfect mix: recent progress in adjuvant research

21 January 2018

1 reference

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

21 January 2018

1 reference

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

21 January 2018

1 reference

Contribution of transmembrane tumor necrosis factor to host defense against Mycobacterium bovis bacillus Calmette-guerin and Mycobacterium tuberculosis infections.

21 January 2018

1 reference

Therapeutic vaccination for chronic diseases: a new class of drugs in sight

21 January 2018

1 reference

A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis

21 January 2018

1 reference

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

21 January 2018

1 reference

A potential immunotherapy approach: mucosal immunization with an IL-13 peptide-based virus-like particle vaccine in a mouse asthma model

21 January 2018

1 reference

A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial

21 January 2018

1 reference

Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice.

21 January 2018

1 reference

Cytokine vaccination: neutralising IL-1alpha autoantibodies induced by immunisation with homologous IL-1alpha

21 January 2018

1 reference

A recombinant DNA plasmid encoding the human interleukin-5 breaks immunological tolerance and inhibits airway inflammation in a murine model of asthma

21 January 2018

1 reference

Knocking out IL-6 by vaccination.

21 January 2018

1 reference

Induction of TNF-alpha autoantibody production by AutoVac TNF106: a novel therapeutic approach for the treatment of allergic diseases

21 January 2018

1 reference

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

21 January 2018

1 reference

Anti-TNF-alpha antibody allows healing of joint damage in polyarthritic transgenic mice

21 January 2018

1 reference

Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis

21 January 2018

1 reference

Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model

21 January 2018

1 reference

Interleukin-17 is a negative regulator of established allergic asthma

21 January 2018

1 reference

Anti-cytokine therapeutics: history and update

21 January 2018

1 reference

Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective French Research Axed on Tolerance of Biotherapies registry

21 January 2018

1 reference

The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 person-years of observation

21 January 2018

1 reference

Lymphoma in patients treated with anti-TNF: results of the 3-year prospective French RATIO registry

21 January 2018

1 reference

Safety of anti-tumor necrosis factor therapy in inflammatory bowel disease

21 January 2018

1 reference

Crohn's disease: beyond antagonists of tumour necrosis factor

21 January 2018

1 reference

Optimizing anti-TNF treatment in inflammatory bowel disease

21 January 2018

1 reference

Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

21 January 2018

1 reference

Certolizumab pegol for the treatment of Crohn's disease

21 January 2018

1 reference

Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review

21 January 2018

1 reference

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.

21 January 2018

1 reference

Characterization and potential clinical applications of autoantibodies against cytokines

21 January 2018

1 reference

FDA review of a panitumumab (Vectibix) clinical trial for first-line treatment of metastatic colorectal cancer

21 January 2018

1 reference

Cetuximab: in the treatment of metastatic colorectal cancer

21 January 2018

1 reference

First-line Herceptin monotherapy in metastatic breast cancer

21 January 2018

1 reference

Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer

21 January 2018

1 reference

Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in first-line metastatic colorectal cancer.

21 January 2018

1 reference

Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study

21 January 2018

1 reference

Use of canakinumab in the cryopyrin-associated periodic syndrome

21 January 2018

1 reference

Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma

21 January 2018

1 reference

Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

21 January 2018

1 reference

Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers

21 January 2018

1 reference

21 January 2018

1 reference

IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys

21 January 2018

1 reference

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

21 January 2018

1 reference

Fontolizumab in moderate to severe Crohn's disease: a phase 2, randomized, double-blind, placebo-controlled, multiple-dose study

21 January 2018

1 reference

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

21 January 2018

1 reference

Immunodrugs: therapeutic VLP-based vaccines for chronic diseases

21 January 2018

1 reference

Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles

21 January 2018

1 reference

A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus

21 January 2018

1 reference

Prevention of experimental autoimmune encephalomyelitis by MIP-1alpha and MCP-1 naked DNA vaccines

21 January 2018

1 reference

A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis

21 January 2018

1 reference

Bioimmunotherapy for melanoma using fully human antibodies targeting MCAM/MUC18 and IL-8.

21 January 2018

1 reference

Generation and analysis of interleukin-4 deficient mice

21 January 2018

1 reference

Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/IMT.10.16

1 reference

22 August 2017

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