(Q37776719)

23 August 2017

1 reference

title

Chloroplasts as expression platforms for plant-produced vaccines (English)

1 reference

23 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20673012

13 June 2024

1

Teodoro Cardi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20673012

13 June 2024

author name string

Paolo Lenzi

2

1 reference

23 August 2017

Pal Maliga

3

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20673012

13 June 2024

publication date

1 August 2010

1 reference

full work available at URL

23 August 2017

http://www.future-drugs.com/doi/abs/10.1586/erv.10.78

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20673012

http://www.tandfonline.com/doi/pdf/10.1586/erv.10.78

13 June 2024

1 reference

Expert Review of Vaccines

13 June 2024

published in

1 reference

23 August 2017

volume

9

1 reference

23 August 2017

issue

8

1 reference

23 August 2017

page(s)

893-911

1 reference

Expression of hepatitis B surface antigen in transgenic plants

23 August 2017

cites work

1 reference

Plant-made vaccine antigens and biopharmaceuticals

21 January 2018

1 reference

Plant-derived vaccines and antibodies: potential and limitations

21 January 2018

1 reference

Recent progress in the development of plant derived vaccines

21 January 2018

1 reference

From planta to pharma with glycosylation in the toolbox.

21 January 2018

1 reference

Plant-produced vaccines: promise and reality

21 January 2018

1 reference

A guide to choosing vectors for transformation of the plastid genome of higher plants

21 January 2018

1 reference

Plastid transformation in higher plants

21 January 2018

1 reference

Chloroplast vector systems for biotechnology applications

21 January 2018

1 reference

Stable transformation of plastids in higher plants

21 January 2018

1 reference

High-frequency plastid transformation in tobacco by selection for a chimeric aadA gene

21 January 2018

1 reference

Chlamydomonas reinhardtii chloroplasts as protein factories.

21 January 2018

1 reference

Factors effecting expression of vaccines in microalgae

21 January 2018

1 reference

Chloroplast translation regulation

21 January 2018

1 reference

Plastid transcriptomics and translatomics of tomato fruit development and chloroplast-to-chromoplast differentiation: chromoplast gene expression largely serves the production of a single protein.

21 January 2018

1 reference

Genome-wide analysis of plastid gene expression in potato leaf chloroplasts and tuber amyloplasts: transcriptional and posttranscriptional control

21 January 2018

1 reference

Engineering the plastid genome of higher plants

21 January 2018

1 reference

Progress towards commercialization of plastid transformation technology

21 January 2018

1 reference

Inducible trans-activation of plastid transgenes: expression of the R. eutropha phb operon in transplastomic tobacco.

21 January 2018

1 reference

T7 RNA polymerase-directed expression of an antibody fragment transgene in plastids causes a semi-lethal pale-green seedling phenotype

21 January 2018

1 reference

Controlled expression of plastid transgenes in plants based on a nuclear DNA-encoded and plastid-targeted T7 RNA polymerase

21 January 2018

1 reference

Plastid transformation of high-biomass tobacco variety Maryland Mammoth for production of human immunodeficiency virus type 1 (HIV-1) p24 antigen.

21 January 2018

1 reference

High-level expression of human immunodeficiency virus antigens from the tobacco and tomato plastid genomes.

21 January 2018

1 reference

Genetic engineering of the chloroplast

21 January 2018

1 reference

A galinstan expansion femtosyringe for microinjection of eukaryotic organelles and prokaryotes.

21 January 2018

1 reference

Transgenic plastids in basic research and plant biotechnology

21 January 2018

1 reference

Chloroplast transformation in plants: polyethylene glycol (PEG) treatment of protoplasts is an alternative to biolistic delivery systems

21 January 2018

1 reference

Kanamycin resistance as a selectable marker for plastid transformation in tobacco.

21 January 2018

1 reference

Stable transformation of the cotton plastid genome and maternal inheritance of transgenes

21 January 2018

1 reference

Tobacco plastid transformation using the feedback-insensitive anthranilate synthase [alpha]-subunit of tobacco (ASA2) as a new selectable marker

21 January 2018

1 reference

Tools for chloroplast transformation in Chlamydomonas: expression vectors and a new dominant selectable marker.

21 January 2018

1 reference

Transgenic expression of aminoglycoside adenine transferase in the chloroplast: a selectable marker of site-directed transformation of chlamydomonas

21 January 2018

1 reference

A small chloroplast RNA may be required for trans-splicing in chlamydomonas reinhardtii

21 January 2018

1 reference

The ARG9 gene encodes the plastid-resident N-acetyl ornithine aminotransferase in the green alga Chlamydomonas reinhardtii

21 January 2018

1 reference

High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts.

21 January 2018

1 reference

Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco.

21 January 2018

1 reference

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic.

21 January 2018

1 reference

Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challenge

21 January 2018

1 reference

Transgenic chloroplasts are efficient sites for high-yield production of the vaccinia virus envelope protein A27L in plant cellsdagger

21 January 2018

1 reference

Next generation synthetic vectors for transformation of the plastid genome of higher plants

21 January 2018

1 reference

Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism.

21 January 2018

1 reference

Control of protein life-span by N-terminal methionine excision

21 January 2018

1 reference

Expression of recombinant proteins lacking methionine as N-terminal amino acid in plastids: human serum albumin as a case study.

21 January 2018

1 reference

Plastid biotechnology: prospects for herbicide and insect resistance, metabolic engineering and molecular farming

21 January 2018

1 reference

Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts

21 January 2018

1 reference

Production of a recombinant bacterial lipoprotein in higher plant chloroplasts

21 January 2018

1 reference

High-yield production of a human therapeutic protein in tobacco chloroplasts

21 January 2018

1 reference

Expression of tetanus toxin Fragment C in tobacco chloroplasts

21 January 2018

1 reference

Hybrid transcription-mediated transgene regulation in plastids

21 January 2018

1 reference

Gene activation in plastids by the CRE site-specific recombinase.

21 January 2018

1 reference

Artificial control of transgene expression in Chlamydomonas reinhardtii chloroplast using the lac regulation system from Escherichia coli.

21 January 2018

1 reference

Potential for hydrogen production with inducible chloroplast gene expression in Chlamydomonas

21 January 2018

1 reference

Determining the transgene containment level provided by chloroplast transformation

21 January 2018

1 reference

Exceptional transmission of plastids and mitochondria from the transplastomic pollen parent and its impact on transgene containment

21 January 2018

1 reference

Spontaneous capture of oilseed rape (Brassica napus) chloroplasts by wild B. rapa: implications for the use of chloroplast transformation for biocontainment.

21 January 2018

1 reference

Improving containment strategies in biopharming

21 January 2018

1 reference

Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery

21 January 2018

1 reference

Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts.

21 January 2018

1 reference

Bioterrorism: management of major biological agents

21 January 2018

1 reference

Expression of Bacillus anthracis protective antigen in transgenic chloroplasts of tobacco, a non-food/feed crop

21 January 2018

1 reference

Expression of an Escherichia coli antigenic fusion protein comprising the heat labile toxin B subunit and the heat stable toxin, and its assembly as a functional oligomer in transplastomic tobacco plants

21 January 2018

1 reference

Expression of the B subunit of E. coli heat-labile enterotoxin in the chloroplasts of plants and its characterization.

21 January 2018

1 reference

Expression of non-toxic mutant of Escherichia coli heat-labile enterotoxin in tobacco chloroplasts.

21 January 2018

1 reference

Expression of a multi-epitope DPT fusion protein in transplastomic tobacco plants retains both antigenicity and immunogenicity of all three components of the functional oligomer.

21 January 2018

1 reference

Expression of the recombinant bacterial outer surface protein A in tobacco chloroplasts leads to thylakoid localization and loss of photosynthesis

21 January 2018

1 reference

Heat-stable oral alga-based vaccine protects mice from Staphylococcus aureus infection.

21 January 2018

1 reference

Expression of rotavirus capsid protein VP6 in transgenic potato and its oral immunogenicity in mice

21 January 2018

1 reference

Virus-like particle vaccines and adjuvants: the HPV paradigm

21 January 2018

1 reference

HPV Vaccines: today and in the Future

21 January 2018

1 reference

Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic

21 January 2018

1 reference

Oral immunogenicity of human papillomavirus-like particles expressed in potato

21 January 2018

1 reference

Potato virus X coat protein fusion to human papillomavirus 16 E7 oncoprotein enhance antigen stability and accumulation in tobacco chloroplast.

21 January 2018

1 reference

Antitumor activity of DNA vaccines based on the human papillomavirus-16 E7 protein genetically fused to a plant virus coat protein

21 January 2018

1 reference

Plants as biofactories for the production of subunit vaccines against bio-security-related bacteria and viruses.

21 January 2018

1 reference

High-yield expression of a viral peptide animal vaccine in transgenic tobacco chloroplasts.

21 January 2018

1 reference

A novel methodology to develop a foot and mouth disease virus (FMDV) peptide-based vaccine in transgenic plants.

21 January 2018

1 reference

High expression of foot-and-mouth disease virus structural protein VP1 in tobacco chloroplasts

21 January 2018

1 reference

Foot-and-mouth disease virus VP1 protein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast

21 January 2018

1 reference

Recombination and expression of classical swine fever virus (CSFV) structural protein E2 gene in Chlamydomonas reinhardtii chroloplasts.

21 January 2018

1 reference

The expression of classical swine fever virus structural protein E2 gene in tobacco chloroplasts for applying chloroplasts as bioreactors

21 January 2018

1 reference

Expression of viral capsid protein antigen against Epstein-Barr virus in plastids of Nicotiana tabacum cv. SR1.

21 January 2018

1 reference

Stable expression of Gal/GalNAc lectin of Entamoeba histolytica in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasis

21 January 2018

1 reference

Immunity to malaria: more questions than answers

21 January 2018

1 reference

Immune responses to dietary antigens: oral tolerance.

21 January 2018

1 reference

Expression of cholera toxin B-proinsulin fusion protein in lettuce and tobacco chloroplasts--oral administration protects against development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65).

21 January 2018

1 reference

Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4.

21 January 2018

1 reference

The vaccine adjuvant extra domain A from fibronectin retains its proinflammatory properties when expressed in tobacco chloroplasts

21 January 2018

1 reference

Plastid-expressed 5-enolpyruvylshikimate-3-phosphate synthase genes provide high level glyphosate tolerance in tobacco

21 January 2018

1 reference

Stable plastid transformation in lettuce (Lactuca sativa L.).

21 January 2018

1 reference

Translocation of aprotinin, a therapeutic protease inhibitor, into the thylakoid lumen of genetically engineered tobacco chloroplasts

21 January 2018

1 reference

Tobacco, a highly efficient green bioreactor for production of therapeutic proteins

21 January 2018

1 reference

Pharma-Planta: road testing the developing regulatory guidelines for plant-made pharmaceuticals

21 January 2018

1 reference

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants

21 January 2018

1 reference

Plant-derived pharmaceuticals--the road forward

21 January 2018

1 reference

Evolution of a regulatory framework for pharmaceuticals derived from genetically modified plants.

21 January 2018

1 reference

Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors.

21 January 2018

1 reference

In planta protein sialylation through overexpression of the respective mammalian pathway

21 January 2018

1 reference

Down-regulated expression of plant-specific glycoepitopes in alfalfa

21 January 2018

1 reference

Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview

21 January 2018

1 reference

Plant derived veterinary vaccines

21 January 2018

1 reference

Chapter 17: Second generation HPV vaccines to prevent cervical cancer

21 January 2018

1 reference

Immunobiology of human papillomavirus infection and vaccination - implications for second generation vaccines.

21 January 2018

1 reference

Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor

21 January 2018

1 reference

Targeted knockouts of Physcomitrella lacking plant-specific immunogenic N-glycans

21 January 2018

1 reference

Fluorescent antibiotic resistance marker for tracking plastid transformation in higher plants

21 January 2018

1 reference

Stable genetic transformation of tomato plastids and expression of a foreign protein in fruit

21 January 2018

1 reference

Marker free transgenic plants: engineering the chloroplast genome without the use of antibiotic selection

21 January 2018

1 reference

Plastid transformation in Lesquerella fendleri, an oilseed Brassicacea

21 January 2018

1 reference

Chloroplast transformation in oilseed rape.

21 January 2018

1 reference

Plastid-expressed betaine aldehyde dehydrogenase gene in carrot cultured cells, roots, and leaves confers enhanced salt tolerance

21 January 2018

1 reference

Stable transformation of petunia plastids

21 January 2018

1 reference

Generation of fertile transplastomic soybean.

21 January 2018

1 reference

Plastid transformants of tomato selected using mutations affecting ribosome structure.

21 January 2018

1 reference

Efficient and stable transformation of Lactuca sativa L. cv. Cisco (lettuce) plastids.

21 January 2018

1 reference

Transformation of poplar (Populus alba) plastids and expression of foreign proteins in tree chloroplasts

21 January 2018

1 reference

Simple and efficient plastid transformation system for the liverwort Marchantia polymorpha L. suspension-culture cells.

21 January 2018

1 reference

Stable chloroplast transformation in cabbage (Brassica oleracea L. var. capitata L.) by particle bombardment

21 January 2018

1 reference

Genetic transformation of the sugar beet plastome.

21 January 2018

1 reference

Plastid transformation in eggplant (Solanum melongena L.).

21 January 2018

1 reference

Chloroplast transformation of rapeseed (Brassica napus) by particle bombardment of cotyledons

21 January 2018

1 reference

High expression level of a foot and mouth disease virus epitope in tobacco transplastomic plants

21 January 2018

1 reference

The expression of a nopaline synthase ? human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue

21 January 2018

1

1 reference

Studies on Chlamydomonas chloroplast transformation: foreign DNA can be stably maintained in the chromosome

13 June 2024

11

1 reference

Chloroplast transformation in Chlamydomonas with high velocity microprojectiles

13 June 2024

12

1 reference

Analysis of gene expression in amyloplasts of potato tubers

13 June 2024

25

1 reference

Pre-screening plastid transgene expression cassettes in Escherichia coli may be unreliable as a predictor of expression levels in chloroplast-transformed plants

13 June 2024

33

1 reference

Sequences downstream of the translation initiation codon are important determinants of translation efficiency in chloroplasts

13 June 2024

35

1 reference

Extensive homologous recombination between introduced and native regulatory plastid DNA elements in transplastomic plants

13 June 2024

36

1 reference

Expression of green fluorescent protein from bacterial and plastid promoters in tobacco chloroplasts

13 June 2024

40

1 reference

Efficient plastid transformation in tobacco using the aphA-6 gene and kanamycin selection

13 June 2024

46

1 reference

Transformation of chloroplast ribosomal RNA genes in Chlamydomonas: molecular and genetic characterization of integration events

13 June 2024

52

1 reference

Nonrandom distribution of chloroplast recombination events in Chlamydomonas reinhardtii: evidence for a hotspot and an adjacent cold region

13 June 2024

53

1 reference

Site-specific mutagenesis of the D1 subunit of photosystem II in wild-type Chlamydomonas

13 June 2024

54

1 reference

Accumulation of rotavirus VP6 protein in chloroplasts of transplastomic tobacco is limited by protein stability

13 June 2024

58

1 reference

Development of novel types of plastid transformation vectors and evaluation of factors controlling expression

13 June 2024

64

1 reference

Both the stroma and thylakoid lumen of tobacco chloroplasts are competent for the formation of disulphide bonds in recombinant proteins

13 June 2024

71

1 reference

Hybrid transcription system for controlled plastid transgene expression

13 June 2024

78

1 reference

External control of transgene expression in tobacco plastids using the bacterial lac repressor

13 June 2024

80

1 reference

Protection against tetanus toxin using a plant-based vaccine

13 June 2024

89

1 reference

Production of immunogenic VP6 protein of bovine group A rotavirus in transgenic potato plants

13 June 2024

101

1 reference

Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike particles

13 June 2024

103

1 reference

Production of HIV-1 p24 protein in transgenic tobacco plants

13 June 2024

104

1 reference

Induction of neutralizing antibodies by a tobacco chloroplast-derived vaccine based on a B cell epitope from canine parvovirus

13 June 2024

113

1 reference

Expression and Characterization of Synthetic Heat-Labile Enterotoxin B Subunit and Hemagglutinin–Neuraminidase-Neutralizing Epitope Fusion Protein in Escherichia coli and Tobacco Chloroplasts

13 June 2024

121

1 reference

A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice

13 June 2024

122

1 reference

The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo

13 June 2024

133

1 reference

Technical Advance: Stable chloroplast transformation in potato: use of green fluorescent protein as a plastid marker

13 June 2024

139

1 reference

Plastid transformation reveals that moss tRNA(Arg)-CCG is not essential for plastid function

13 June 2024

140

1 reference

Engineering the plastid genome of Nicotiana sylvestris, a diploid model species for plastid genetics

13 June 2024

147

1 reference

Integration of foreign sequences into the tobacco plastome via polyethylene glycol-mediated protoplast transformation

13 June 2024

155

1 reference

13 June 2024

Identifiers

DOI

10.1586/ERV.10.78

1 reference

23 August 2017

1 reference