(Q37777069)

23 August 2017

1 reference

title

Exciting New Targets in Lung Cancer Therapy: ALK, IGF-1R, HDAC, and Hh (English)

1 reference

https://api.crossref.org/works/10.1007/S11864-010-0120-6

14 June 2024

1 reference

2

Lecia V Sequist

1 reference

23 August 2017

Joel W. Neal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676809

14 June 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20676809

14 June 2024

publication date

1 June 2010

1 reference

full work available at URL

23 August 2017

http://link.springer.com/content/pdf/10.1007/s11864-010-0120-6.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S11864-010-0120-6

http://link.springer.com/article/10.1007/s11864-010-0120-6/fulltext.html

14 June 2024

1 reference

https://api.crossref.org/works/10.1007/S11864-010-0120-6

http://link.springer.com/content/pdf/10.1007/s11864-010-0120-6

14 June 2024

1 reference

https://api.crossref.org/works/10.1007/S11864-010-0120-6

Current Treatment Options in Oncology

14 June 2024

published in

1 reference

23 August 2017

volume

11

1 reference

23 August 2017

issue

1-2

1 reference

23 August 2017

page(s)

36-44

1 reference

A paracrine requirement for hedgehog signalling in cancer

23 August 2017

cites work

1 reference

12 December 2020

Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer.

1 reference

12 December 2020

Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma

1 reference

12 December 2020

Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer.

1 reference

12 December 2020

The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60

1 reference

12 December 2020

Insulin-like growth factor-I, its binding proteins (IGFBP-1 and IGFBP-3), and growth hormone and breast cancer risk in The Nurses Health Study II

1 reference

12 December 2020

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

12 December 2020

Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751,871) in combination with paclitaxel and carboplatin

1 reference

12 December 2020

Carboplatin and Paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer

1 reference

12 December 2020

Histone acetylation and chromatin remodeling

1 reference

12 December 2020

A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry

1 reference

12 December 2020

"Oncogenic shock": explaining oncogene addiction through differential signal attenuation

1 reference

12 December 2020

Frequent requirement of hedgehog signaling in non-small cell lung carcinoma

1 reference

12 December 2020

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

1 reference

12 December 2020

Serum insulin-like growth factor (IGF) and IGF-binding protein levels and risk of lung cancer: a case-control study nested in the beta-Carotene and Retinol Efficacy Trial Cohort

1 reference

12 December 2020

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

1 reference

12 December 2020

Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas

1 reference

12 December 2020

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

1 reference

12 December 2020

Vorinostat (NSC# 701852) in patients with relapsed non-small cell lung cancer: a Wisconsin Oncology Network phase II study

1 reference

12 December 2020

Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

1 reference

12 December 2020

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

12 December 2020

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

1 reference

12 December 2020

A small molecule that binds Hedgehog and blocks its signaling in human cells

1 reference

12 December 2020

Inhibition of insulin-like growth factor 1 receptor by CP-751,871 radiosensitizes non-small cell lung cancer cells

1 reference

12 December 2020

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

1 reference

12 December 2020

Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy

1 reference

12 December 2020

Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts.

1 reference

12 December 2020

Insulin and insulin-like growth factor signalling in neoplasia

1 reference

12 December 2020

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

1 reference

12 December 2020

Histone deacetylase inhibitor romidepsin enhances anti-tumor effect of erlotinib in non-small cell lung cancer (NSCLC) cell lines

1 reference

12 December 2020

ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

1 reference

12 December 2020

Hedgehog signaling in small-cell lung cancer: frequent in vivo but a rare event in vitro.

1 reference

12 December 2020

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

1 reference

12 December 2020

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

1 reference

12 December 2020

Nevoid basal cell carcinoma (Gorlin) syndrome

1 reference

12 December 2020

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

1 reference

12 December 2020

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

12 December 2020

Pathobiology of ALK+ anaplastic large-cell lymphoma

1 reference

12 December 2020

Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK

1 reference

12 December 2020

EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

1 reference

12 December 2020

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

1 reference

12 December 2020

Phase I and pharmacokinetic study of vorinostat, a histone deacetylase inhibitor, in combination with carboplatin and paclitaxel for advanced solid malignancies

1 reference

12 December 2020

Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.

1 reference

12 December 2020

Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population

1 reference

12 December 2020

Insulin and its receptor: structure, function and evolution

1 reference

12 December 2020

Insulin-like growth factors and neoplasia.

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

1 reference

12 December 2020

Adenovirus expressing shRNA to IGF-1R enhances the chemosensitivity of lung cancer cell lines by blocking IGF-1 pathway

1 reference

12 December 2020

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

1 reference

12 December 2020

Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins

1 reference

12 December 2020

Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications

1 reference

12 December 2020

Journal of Clinical Investigation

22

118

2609

M Guix

2008

1 reference

https://api.crossref.org/works/10.1007/S11864-010-0120-6

14 June 2024

Identifiers

1 reference

23 August 2017

1 reference