(Q37789445)

23 August 2017

title

KRAS gene mutations in lung cancer: particulars established and issues unresolved (English)

1 reference

23 August 2017

KRAS gene mutations in lung cancer: Particulars established and issues unresolved (English)

1 reference

https://api.crossref.org/works/10.1111/J.1440-1827.2010.02580.X

14 July 2024

1 reference

1

Koji Okudela

1 reference

23 August 2017

Tetsukan Woo

2

1 reference

23 August 2017

Hitoshi Kitamura

3

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20846262

14 July 2024

publication date

1 October 2010

1 reference

full work available at URL

23 August 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1827.2010.02580.x

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20846262

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1440-1827.2010.02580.x

14 July 2024

1 reference

https://api.crossref.org/works/10.1111/J.1440-1827.2010.02580.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1440-1827.2010.02580.x/fullpdf

14 July 2024

1 reference

https://api.crossref.org/works/10.1111/J.1440-1827.2010.02580.X

14 July 2024

published in

Pathology International

1 reference

23 August 2017

volume

60

1 reference

23 August 2017

issue

10

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23 August 2017

page(s)

651-660

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K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

23 August 2017

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CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells

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Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma

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Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis

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14 July 2024

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Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

14 July 2024

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Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells

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Transforming genes in human tumors

14 July 2024

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Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

14 July 2024

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Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

14 July 2024

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Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line

14 July 2024

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Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

14 July 2024

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Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton

14 July 2024

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Ras signalling and apoptosis

14 July 2024

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14 July 2024

New exchange, new target

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Increasing complexity of the Ras signaling pathway

14 July 2024

26

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A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

14 July 2024

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Mechanism of activation of a human oncogene

14 July 2024

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Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change.

14 July 2024

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Cigarette smoking and K-ras mutations in pancreas, lung and colorectal adenocarcinomas: etiopathogenic similarities, differences and paradoxes

14 July 2024

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14 July 2024

COSMIC 2005

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BRAF and RAS mutations in human lung cancer and melanoma

14 July 2024

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Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products

14 July 2024

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Bronchioloalveolar lung carcinomas: K-ras mutations are constant events in the mucinous subtype

14 July 2024

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Mixed mucinous-type and non-mucinous-type adenocarcinoma of the lung: immunohistochemical examination and K- ras gene mutation

14 July 2024

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Distinctive evaluation of nonmucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histologic subtypes and gene mutations

14 July 2024

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Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer

14 July 2024

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Significant association between EGFR-mutated lung adenocarcinoma and past illness from gastric cancer or uterine myoma: its implication in carcinogenesis

14 July 2024

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Prognostic Implication of EGFR, KRAS, and TP53 Gene Mutations in a Large Cohort of Japanese Patients with Surgically Treated Lung Adenocarcinoma

14 July 2024

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Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms

14 July 2024

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Molecular targets for cancer therapy and prevention

14 July 2024

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Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?

14 July 2024

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EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

14 July 2024

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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

14 July 2024

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Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

14 July 2024

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Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas

14 July 2024

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Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer

14 July 2024

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Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

14 July 2024

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

14 July 2024

49

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Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non small-cell lung cancer

14 July 2024

50

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Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer

14 July 2024

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Prognostic and Therapeutic Implications of EGFR and KRAS Mutations in Resected Lung Adenocarcinoma

14 July 2024

52

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The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis

14 July 2024

53

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Are RAS mutations predictive markers of resistance to standard chemotherapy?

14 July 2024

54

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RAS inhibitors: potential for cancer therapeutics

14 July 2024

55

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Inhibitors of chronically active ras: potential for treatment of human malignancies.

14 July 2024

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Atypical adenomatous hyperplasia and bronchoalveolar lung carcinoma. Analysis by morphometry and the expressions of p53 and carcinoembryonic antigen

14 July 2024

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Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

14 July 2024

60

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

14 July 2024

61

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Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

14 July 2024

62

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Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

14 July 2024

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Caspase-independent programmed cell death with necrotic morphology

14 July 2024

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ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence

14 July 2024

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Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

14 July 2024

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

14 July 2024

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

14 July 2024

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Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

14 July 2024

70

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BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

14 July 2024

71

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12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione

14 July 2024

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Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis

14 July 2024

73

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Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin

14 July 2024

74

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ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death

14 July 2024

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Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-alpha-induced cell death in MCF-7 cells

14 July 2024

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RAS in cellular transformation and senescence

14 July 2024

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History of the events leading to the formulation of the apoptosis concept

14 July 2024

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Senescence of human fibroblasts induced by oncogenic Raf.

14 July 2024

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Oncogenic ras and p53 cooperate to induce cellular senescence

14 July 2024

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Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death

14 July 2024

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Senescence and serration: a new twist to an old tale

14 July 2024

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Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 l

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

14 July 2024

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The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

14 July 2024

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PIK3CA mutation and amplification in human lung cancer

14 July 2024

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

14 July 2024

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

14 July 2024

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Inhibitory effects of cinnamaldehyde on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung carcinogenesis in rasH2 mice

14 July 2024

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Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

14 July 2024

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

14 July 2024

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Growth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia

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14 July 2024

Identifiers

1 reference

23 August 2017

1 reference