(Q37793830)

23 August 2017

Psoriasis: what we have learned from mouse models (English)

1 reference

23 August 2017

4

1 reference

23 August 2017

Erwin F Wagner

1

0 references

author name string

Helia B Schonthaler

series ordinal

2

1 reference

PubMed ID

20877306

23 August 2017

Juan Guinea-Viniegra

series ordinal

3

1 reference

PubMed ID

20877306

23 August 2017

language of work or name

English

0 references

publication date

28 September 2010

1 reference

Nature Reviews Rheumatology

23 August 2017

1 reference

23 August 2017

6

1 reference

23 August 2017

12

1 reference

23 August 2017

704-714

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.157

23 August 2017

0 references

cites work

Pathogenesis and clinical features of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The Koebner phenomenon: review of the literature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

ARA NOMENCLATURE AND CLASSIFICATION OF ARTHRITIS AND RHEUMATISM (TENTATIVE).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The prevalence of psoriatic arthritis in people with psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Enthesitis: an autoinflammatory lesion linking nail and joint involvement in psoriatic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Plaque psoriasis vs. atopic dermatitis and lichen planus: a comparison for lesional T-cell subsets, epidermal proliferation and differentiation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Skin-resident T cells: the ups and downs of on site immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

An update on the genetics of psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Genetic variations in cytokines and cytokine receptors associated with psoriasis found by genome-wide association

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Pathogenesis and therapy of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Photocarcinogenesis in human adult skin grafts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Regulation of skin cell homeostasis by gamma delta T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Modelling cancer in human skin tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The human hair follicle: glycoprotein-related antigenic profile of distinct keratinocyte populations in vivo and their alterations in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Skin immune sentinels in health and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Epidermal homeostasis: a balancing act of stem cells in the skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Epidermal stem cells: an update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Mouse models of psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Update on the natural history and systemic treatment of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Resident and "inflammatory" dendritic cells in human skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Immunopathogenesis and role of T cells in psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The IL-23/Th17 axis in the immunopathogenesis of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The CX3CL1-CX3CR1 system and psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Immunopathogenesis of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Animal models of psoriasis and psoriatic arthritis: an update.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Animal models of psoriasis - what can we learn from them?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

A hypothesis on the cause of chronic epidermal hyperproliferation in asebia mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Therapeutic interventions in mice with chronic proliferative dermatitis (cpdm/cpdm)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

CD18 in monogenic and polygenic inflammatory processes of the skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

STAT signaling in head and neck cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

VEGF differentially activates STAT3 in microvascular endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Downregulation of TGFβ isoforms and their receptors contributes to keratinocyte hyperproliferation in psoriasis vulgaris

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Overexpression of transforming growth factor alpha in psoriatic epidermis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Transforming growth factor-?1 localization in normal and psoriatic epidermal keratinocytes in situ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopecia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Future perspectives in the treatment of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Inflammatory skin disease in K14/p40 transgenic mice: evidence for interleukin-12-like activities of p40.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Counter-regulation of interleukin-1alpha (IL-1alpha) and IL-1 receptor antagonist in murine keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Interleukin-1: A key inflammatory mediator in psoriasis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Fos and jun proteins are specifically expressed during differentiation of human keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Murine psoriasis-like disorder induced by naive CD4+ T cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

MicroRNAs and potential target interactions in psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

IL-6 in autoimmune disease and chronic inflammatory proliferative disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Interleukin 20: discovery, receptor identification, and role in epidermal function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, and Hair Loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.157

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice

31 March 2020

1 reference

12 December 2020

The status of biologic therapies in the treatment of moderate to severe psoriasis

1 reference

12 December 2020

Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice.

1 reference

12 December 2020

A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice

1 reference

12 December 2020

IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.157

1 reference

23 August 2017

1 reference

PubMed ID

20877306