(Q37802750)

23 August 2017

title

Cancer-associated IDH mutations: biomarker and therapeutic opportunities (English)

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23 August 2017

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K E Yen

1

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23 August 2017

M A Bittinger

series ordinal

2

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23 August 2017

S M Su

series ordinal

3

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23 August 2017

V R Fantin

series ordinal

4

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23 August 2017

language of work or name

English

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publication date

25 October 2010

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23 August 2017

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23 August 2017

volume

29

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23 August 2017

issue

49

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23 August 2017

page(s)

6409-6417

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https://scigraph.springernature.com/pub.10.1038/onc.2010.444

23 August 2017

exact match

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IDH1 mutations in gliomas: when an enzyme loses its grip

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Oxidation of gamma-hydroxybutyrate to succinic semialdehyde by a mitochondrial pyridine nucleotide-independent enzyme.

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Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

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NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria

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31 March 2020

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Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer

31 March 2020

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

31 March 2020

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IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms.

31 March 2020

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31 March 2020

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31 March 2020

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IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

31 March 2020

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31 March 2020

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31 March 2020

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Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

31 March 2020

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

31 March 2020

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31 March 2020

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31 March 2020

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IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.

31 March 2020

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

31 March 2020

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Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions

31 March 2020

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

31 March 2020

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.444

Targeting the epidermal growth factor receptor in high-grade astrocytomas

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.444

The multistep nature of cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

IDH1 and IDH2 mutations in gliomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.444

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.444

1 reference

23 August 2017

1 reference