(Q37840095)

24 August 2017

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title

Neurobiological aspects of Alzheimer's disease (English)

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24 August 2017

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Kanwaljit Chopra

1

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24 August 2017

Shubham Misra

series ordinal

2

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24 August 2017

Anurag Kuhad

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

11 February 2011

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Expert Opinion on Therapeutic Targets

24 August 2017

published in

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24 August 2017

volume

15

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24 August 2017

issue

5

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24 August 2017

page(s)

535-555

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Alzheimer's disease; taking the edge off with cannabinoids?

24 August 2017

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Intracellular amyloid-beta in Alzheimer's disease

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Acetyl-L-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats

21 January 2018

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Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents

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Inflammation, genes and zinc in Alzheimer's disease.

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Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

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Alzheimer disease, the two-hit hypothesis: an update

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Alzheimer's disease: the two-hit hypothesis

21 January 2018

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Pathological and biochemical alterations of astrocytes in ovariectomized rats injected with D-galactose: a potential contribution to Alzheimer's disease processes

21 January 2018

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Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice

21 January 2018

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Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months

21 January 2018

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Inhibition of hippocampal function in mild cognitive impairment: targeting the cholinergic hypothesis

21 January 2018

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Characterization of amyloid

21 January 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 January 2018

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

21 January 2018

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Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg?

21 January 2018

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The Oregon brain aging study: neuropathology accompanying healthy aging in the oldest old.

21 January 2018

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Cdk5, a therapeutic target for Alzheimer's disease?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

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Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

21 January 2018

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Cdk5 is a key factor in tau aggregation and tangle formation in vivo

21 January 2018

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Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

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21 January 2018

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Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Blood activity of Cu/Zn superoxide dismutase, glutathione peroxidase and catalase in Alzheimer's disease: a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

The evolution of free radicals and oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Free radicals, antioxidants, and nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Antioxidant activity and phenolic compounds in selected herbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Mitochondrial bioenergetics and structural network organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Mitochondrial control of neuron death and its role in neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Mitochondria and neuronal activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Ca2+-dependent mechanisms of presynaptic control at central synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Mitochondria and neurotransmission: evacuating the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Causes of oxidative stress in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Alzheimer Disease and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Microglia in the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Neuroscience. Brain under surveillance: the microglia patrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

The role of inflammation in CNS injury and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

The cholinergic anti-inflammatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Expression and function of inducible nitric oxide synthase in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Role of insulin-like growth factor I signaling in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Current pharmacotherapy for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Combination therapy in Alzheimer's disease: a review of current evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Alterations in cholinergic and non‐cholinergic neurotransmitter receptor densities in transgenic Tg2576 mouse brain with β‐amyloid plaque pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Reduction of basal forebrain cholinergic system parallels cognitive impairment in patients at high risk of developing Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Individual differences in aging: behavioral and neurobiological correlates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Impaired sympathetic nervous system response to cognitive effort in early Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Recovery of function after neurotoxic damage to the hippocampal CA3 region: importance of postoperative recovery interval and task experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Neurotoxic action of kainic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Effects of scopolamine and unilateral lesions of the basal forebrain on T-maze spatial discrimination and alternation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Neurofibrillary axonal pathology in aluminum intoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

An hypothesis on the role of glucose in the mechanism of action of cognitive enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Effects of calyculin A and okadaic acid on acetylcholine release and subcellular distribution in rat hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Intracerebroventricular but not intraperitoneal administration of aluminum attenuates vasopressin-enhanced retrieval of a passive avoidance task in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.557363

10.1517/14728222.2011.557363

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

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