(Q37863129)

24 August 2017

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title

The cytoskeleton in nonalcoholic steatohepatitis: 100 years old but still youthful (English)

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24 August 2017

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4

Pavel Strnad

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24 August 2017

2

Johannes Haybaeck

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24 August 2017

Agnes Molnar

1

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24 August 2017

Carolin Lackner

series ordinal

3

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24 August 2017

publication date

1 April 2011

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Expert Review of Gastroenterology & Hepatology

24 August 2017

published in

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24 August 2017

volume

5

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24 August 2017

issue

2

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24 August 2017

page(s)

167-177

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Mechanisms of disease progression in nonalcoholic fatty liver disease

24 August 2017

cites work

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Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies.

21 January 2018

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Cytosolic lipid droplets increase in size by microtubule-dependent complex formation

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PLD1 and ERK2 regulate cytosolic lipid droplet formation

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Regulation of cell-cell junctions by the cytoskeleton.

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Actin, a central player in cell shape and movement

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From signaling pathways to microtubule dynamics: the key players.

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Beyond polymer polarity: how the cytoskeleton builds a polarized cell

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Cellular motility driven by assembly and disassembly of actin filaments

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Control of actin filament treadmilling in cell motility

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Actin dynamics: from nanoscale to microscale

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Abp1p and cortactin, new "hand-holds" for actin

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Ena/VASP: towards resolving a pointed controversy at the barbed end

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Ins and outs of ADF/cofilin activity and regulation

21 January 2018

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Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.

21 January 2018

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ADF/cofilin: a functional node in cell biology

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Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover

21 January 2018

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Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers

21 January 2018

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Coronin switches roles in actin disassembly depending on the nucleotide state of actin

21 January 2018

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Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

21 January 2018

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Direct interaction of microtubule- and actin-based transport motors

21 January 2018

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Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells

21 January 2018

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Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes

21 January 2018

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Structural insights into microtubule function

21 January 2018

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Mechanics of microtubules.

21 January 2018

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Gamma-tubulin complexes and microtubule organization

21 January 2018

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Predominant regulators of tubulin monomer-polymer partitioning and their implication for cell polarization

21 January 2018

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Microtubule-severing enzymes

21 January 2018

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Plus-end-tracking proteins and their interactions at microtubule ends

21 January 2018

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Walking the walk: how kinesin and dynein coordinate their steps

21 January 2018

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Kinesin superfamily motor proteins and intracellular transport

21 January 2018

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Unique post-translational modifications in specialized microtubule architecture

21 January 2018

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Functional specialization of stable and dynamic microtubules in protein traffic in WIF-B cells

21 January 2018

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STAT5B-mediated growth hormone signaling is organized by highly dynamic microtubules in hepatic cells.

21 January 2018

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Subcellular distribution of the glucocorticoid receptor and evidence for its association with microtubules

21 January 2018

1 reference

Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton

21 January 2018

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Intermediate filament assembly: dynamics to disease

21 January 2018

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Toward unraveling the complexity of simple epithelial keratins in human disease

21 January 2018

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Focal adhesions are hotspots for keratin filament precursor formation

21 January 2018

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The keratin-filament cycle of assembly and disassembly.

21 January 2018

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Actin-dependent dynamics of keratin filament precursors

21 January 2018

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Cellular integrity plus: organelle-related and protein-targeting functions of intermediate filaments.

21 January 2018

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"Heads and tails" of intermediate filament phosphorylation: multiple sites and functional insights.

21 January 2018

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Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.

21 January 2018

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Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity

21 January 2018

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Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations.

21 January 2018

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Visualizing the replication cycle of bunyamwera orthobunyavirus expressing fluorescent protein-tagged Gc glycoprotein

21 January 2018

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Intermediate filaments take the heat as stress proteins

21 January 2018

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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

21 January 2018

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Nonalcoholic steatohepatitis: risk factors and diagnosis

21 January 2018

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Alcohol-induced alterations of the hepatocyte cytoskeleton

21 January 2018

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Alteration of microtubule physiology in hepatocytes by insulin.

21 January 2018

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Insulin resistance in nonalcoholic fatty liver disease.

21 January 2018

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Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats.

21 January 2018

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Intermediate filament cytoskeleton of the liver in health and disease

21 January 2018

1 reference

Cytokeratin markers come of age.

21 January 2018

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Cytokeratin-18 fragments and biomarkers of the metabolic syndrome in nonalcoholic steatohepatitis

21 January 2018

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Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

21 January 2018

1 reference

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis.

21 January 2018

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Serum M30 levels: a potential biomarker of severe liver disease in nonalcoholic fatty liver disease and normal aminotransferase levels

21 January 2018

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Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease

21 January 2018

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The clinical utility of biomarkers and the nonalcoholic steatohepatitis CRN liver biopsy scoring system in patients with nonalcoholic fatty liver disease

21 January 2018

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Severe hepatocellular injury with apoptosis induced by a hepatitis C polymerase inhibitor

21 January 2018

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Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study

21 January 2018

1 reference

Monitoring of epithelial cell caspase activation via detection of durable keratin fragment formation.

21 January 2018

1 reference

The keratin cytoskeleton in liver diseases

21 January 2018

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Nonalcoholic steatohepatitis. Clinicopathological comparison with alcoholic hepatitis in ambulatory and hospitalized patients.

21 January 2018

1 reference

From Mallory to Mallory-Denk bodies: what, how and why?

21 January 2018

1 reference

Morphology of alcoholic liver disease

21 January 2018

1 reference

21 January 2018

Mallory bodies revisited

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Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease

21 January 2018

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Histopathology of pediatric nonalcoholic fatty liver disease.

21 January 2018

1 reference

NAFLD in children: a prospective clinical-pathological study and effect of lifestyle advice

21 January 2018

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Clinical and histological features of nonalcoholic fatty liver disease in children

21 January 2018

1 reference

Formation and involution of Mallory bodies ("alcoholic hyalin") in murine and human liver revealed by immunofluorescence microscopy with antibodies to prekeratin

21 January 2018

1 reference

The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury.

21 January 2018

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Proposal for a histological scoring and grading system for non-alcoholic fatty liver disease

21 January 2018

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Design and validation of a histological scoring system for nonalcoholic fatty liver disease

21 January 2018

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Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity

21 January 2018

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Nonalcoholic steatohepatitis--a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients

21 January 2018

1 reference

Hepatocellular ballooning in NASH.

21 January 2018

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Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates

21 January 2018

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Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies

21 January 2018

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Keratin 8 overexpression promotes mouse Mallory body formation

21 January 2018

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"Toxic memory" via chaperone modification is a potential mechanism for rapid Mallory-Denk body reinduction.

21 January 2018

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Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation.

21 January 2018

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Autophagy and lipids: tightening the knot

21 January 2018

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Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

21 January 2018

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S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory

21 January 2018

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Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress

21 January 2018

1 reference

The mallory body: Morphological, clinical and experimental studies (part 1 of a literature survey)

21 January 2018

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Formation of Cytoskeletal Elements During Mouse Embryogenesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EGH.11.5

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24 August 2017

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