(Q37879191)

24 August 2017

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title

Hepatitis C virus-associated insulin resistance: pathogenic mechanisms and clinical implications (English)

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24 August 2017

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Chao-Hung Hung

1

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24 August 2017

Chuan-Mo Lee

series ordinal

2

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24 August 2017

Sheng-Nan Lu

series ordinal

3

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24 August 2017

language of work or name

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1 May 2011

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Expert Review of Anti-infective Therapy

24 August 2017

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24 August 2017

9

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24 August 2017

5

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24 August 2017

525-533

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Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

24 August 2017

1 reference

Long-term mortality after transfusion-associated non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study Group

21 January 2018

1 reference

Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups

21 January 2018

1 reference

Hepatitis C: a multifaceted disease. Review of extrahepatic manifestations

21 January 2018

1 reference

The spectrum of extrahepatic manifestations in hepatitis C virus infection

21 January 2018

1 reference

Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection

21 January 2018

1 reference

Hepatitis C virus infection and incident type 2 diabetes

21 January 2018

1 reference

Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C.

21 January 2018

1 reference

Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected].

21 January 2018

1 reference

Insulin resistance and insulin secretion in chronic hepatitis C virus infection

21 January 2018

1 reference

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

21 January 2018

1 reference

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

21 January 2018

1 reference

Beta-cell deficiency, insulin resistance, or both?

21 January 2018

1 reference

Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

21 January 2018

1 reference

Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance.

21 January 2018

1 reference

Molecular mechanisms of insulin resistance in chronic hepatitis C

21 January 2018

1 reference

Pathophysiology of insulin resistance.

21 January 2018

1 reference

Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences.

21 January 2018

1 reference

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes

21 January 2018

1 reference

Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C.

21 January 2018

1 reference

Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

21 January 2018

1 reference

Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A.

21 January 2018

1 reference

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

AMP-activated protein kinase: balancing the scales.

21 January 2018

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

21 January 2018

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Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

21 January 2018

1 reference

Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3

21 January 2018

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The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms

21 January 2018

1 reference

Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans

21 January 2018

1 reference

Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy

21 January 2018

1 reference

Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study

21 January 2018

1 reference

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

21 January 2018

1 reference

Interleukin-6 induces cellular insulin resistance in hepatocytes

21 January 2018

1 reference

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

21 January 2018

1 reference

Long-term effects of tumor necrosis factor-alpha treatment on insulin signaling pathway in HepG2 cells and HepG2 cells overexpressing constitutively active Akt/PKB.

21 January 2018

1 reference

Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines

21 January 2018

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Association of inflammatory and anti-inflammatory cytokines with insulin resistance in chronic hepatitis C.

21 January 2018

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Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 January 2018

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Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial.

21 January 2018

1 reference

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

21 January 2018

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Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production

21 January 2018

1 reference

Evidence of oxidative stress as a cofactor in the development of insulin resistance in patients with chronic hepatitis C.

21 January 2018

1 reference

Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy

21 January 2018

1 reference

Hepatitis C and carotid atherosclerosis: a retrospective analysis

21 January 2018

1 reference

Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C

21 January 2018

1 reference

Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C.

21 January 2018

1 reference

The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology

21 January 2018

1 reference

Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.

21 January 2018

1 reference

Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C.

21 January 2018

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Steatosis correlates with hepatic expression of death receptors and activation of nuclear factor-kappaB in chronic hepatitis C.

21 January 2018

1 reference

High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis

21 January 2018

1 reference

Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis

21 January 2018

1 reference

Insulin resistance is a risk factor for esophageal varices in hepatitis C virus cirrhosis.

21 January 2018

1 reference

Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium

21 January 2018

1 reference

Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: a randomized trial.

21 January 2018

1 reference

A randomised study of peginterferon and ribavirin for 16 versus 24 weeks in patients with genotype 2 chronic hepatitis C

21 January 2018

1 reference

Insulin resistance predicts response to peginterferon-alpha/ribavirin combination therapy in chronic hepatitis C patients.

21 January 2018

1 reference

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

21 January 2018

1 reference

Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C.

21 January 2018

1 reference

Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

21 January 2018

1 reference

Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.

21 January 2018

1 reference

SOCS-1 and SOCS-3 inhibit IFN-alpha-induced expression of the antiviral proteins 2,5-OAS and MxA.

21 January 2018

1 reference

Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study

21 January 2018

1 reference

Impact of diabetes mellitus on incidence of hepatocellular carcinoma in chronic hepatitis C patients treated with interferon-based antiviral therapy.

21 January 2018

1 reference

Neither diabetes mellitus nor overweight is a risk factor for hepatocellular carcinoma in a dual HBV and HCV endemic area: community cross-sectional and case-control studies

21 January 2018

1 reference

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

A prospective study of obesity and cancer risk (Sweden).

21 January 2018

1 reference

Obesity and cancer risk: a Danish record-linkage study.

21 January 2018

1 reference

Insulin resistance is associated with hepatocellular carcinoma in chronic hepatitis C infection

21 January 2018

1 reference

Insulin resistance: a metabolic pathway to chronic liver disease

21 January 2018

1 reference

Posttransplant metabolic syndrome: an epidemic waiting to happen

21 January 2018

1 reference

The effect of insulin-dependent diabetes mellitus on outcome of liver transplantation

21 January 2018

1 reference

Factors differentially correlated with the outcome of liver transplantation in hcv+ and HCV- recipients

21 January 2018

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Insulin resistance, serum adipokines and risk of fibrosis progression in patients transplanted for hepatitis C.

21 January 2018

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Insulin resistance and lichen planus in patients with HCV-infectious liver diseases

21 January 2018

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Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C.

21 January 2018

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Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C.

21 January 2018

1 reference

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase-Dependent Regulation of the Orphan Nuclear Receptor SHP

21 January 2018

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Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin

21 January 2018

1 reference

Pioglitazone as adjuvant therapy in chronic hepatitis C: sequential rather than concomitant administration with pegylated interferon and ribavirin?

21 January 2018

1 reference

Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance

21 January 2018

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Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin

21 January 2018

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The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

21 January 2018

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Doctors seek to prevent breast cancer recurrence by lowering insulin levels.

21 January 2018

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Antidiabetic therapies affect risk of pancreatic cancer

21 January 2018

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Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease

21 January 2018

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

21 January 2018

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IL28B and the control of hepatitis C virus infection

21 January 2018

1 reference

Hepatitis C Viremia Increases the Association With Type 2 Diabetes Mellitus in a Hepatitis B and C Endemic Area: An Epidemiological Link With Virological Implication

21 January 2018

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Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus

21 January 2018

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Global Assessment of Regulation of Phosphorylation of Insulin Receptor Substrate-1 by Insulin In Vivo in Human Muscle

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERI.11.33

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24 August 2017

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