(Q37886159)

24 August 2017

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title

Animal models in the study of hepatitis C virus-associated liver pathologies (English)

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24 August 2017

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Jean-Michel Pawlotsky

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object named as

Jean-Michel Pawlotsky

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author name string

Hervé Lerat

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24 August 2017

Martin Higgs

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24 August 2017

Jean-Michel Pawlotsky

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24 August 2017

publication date

1 June 2011

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Expert Review of Gastroenterology & Hepatology

24 August 2017

published in

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24 August 2017

volume

5

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24 August 2017

issue

3

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24 August 2017

page(s)

341-352

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Natural history of chronic hepatitis B and C.

24 August 2017

cites work

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21 January 2018

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Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture

21 January 2018

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Complete replication of hepatitis C virus in cell culture

21 January 2018

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

21 January 2018

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

21 January 2018

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Robust hepatitis C virus infection in vitro

21 January 2018

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A critical role for the chimpanzee model in the study of hepatitis C.

21 January 2018

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Chimpanzee models for human disease and immunobiology

21 January 2018

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Transmission of hepatitis C virus infection to tree shrews

21 January 2018

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Lack of susceptibility of Chacma baboons (Papio ursinus orientalis) to hepatitis C virus infection

21 January 2018

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Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins

21 January 2018

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Hepatitis C virus viremia in SCID-->BNX mouse chimera

21 January 2018

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The hepatitis C virus (HCV)-Trimera mouse: a model for evaluation of agents against HCV.

21 January 2018

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A novel immunocompetent rat model of HCV infection and hepatitis

21 January 2018

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Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

21 January 2018

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Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus

21 January 2018

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uPA+/+-SCID mouse with humanized liver as a model for in vivo metabolism of exogenous steroids: methandienone as a case study.

21 January 2018

1 reference

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera

21 January 2018

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Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus

21 January 2018

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Liver-stage development of Plasmodium falciparum, in a humanized mouse model

21 January 2018

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Hepatitis C virus replication in mice with chimeric human livers

21 January 2018

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Development of humanized mice for the study of hepatitis C virus infection

21 January 2018

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Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

21 January 2018

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The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV.

21 January 2018

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Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

21 January 2018

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Host and viral determinants for engraftment of virus permissive human hepatocytes into chimeric immunodeficient mice

21 January 2018

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A mouse model of inducible liver injury caused by tet-on regulated urokinase for studies of hepatocyte transplantation.

21 January 2018

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Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes

21 January 2018

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Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.

21 January 2018

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Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

21 January 2018

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Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model

21 January 2018

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Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

21 January 2018

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A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease.

21 January 2018

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Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application

21 January 2018

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Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse

21 January 2018

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HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

21 January 2018

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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

21 January 2018

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Determinants of hepatitis C translational initiation in vitro, in cultured cells and mice

21 January 2018

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Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

21 January 2018

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Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation

21 January 2018

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HCV-core protein accelerates recovery from the insensitivity of liver cells to Fas-mediated apoptosis induced by an injection of anti-Fas antibody in mice.

21 January 2018

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Expression of hepatitis C virus core protein associated with malignant lymphoma in transgenic mice

21 January 2018

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Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis

21 January 2018

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Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice

21 January 2018

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Hepatitis C virus core and E2 protein expression in transgenic mice

21 January 2018

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Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model

21 January 2018

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Transgenic expression of Korean type hepatitis C virus core protein and related mutants in mice

21 January 2018

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Expression of hepatitis C virus envelope proteins in transgenic mice

21 January 2018

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Hepatitis C virus structural proteins induce liver cell injury in transgenic mice

21 January 2018

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Transgenic expression of hepatitis C virus structural proteins in the mouse

21 January 2018

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Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production

21 January 2018

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Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

21 January 2018

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Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2.

21 January 2018

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Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system

21 January 2018

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The hepatitis C virus and immune evasion: non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor mediated liver disease

21 January 2018

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Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice

21 January 2018

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Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice

21 January 2018

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Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice

21 January 2018

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Replication of a hepatitis C virus replicon clone in mouse cells

21 January 2018

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Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection

21 January 2018

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Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

21 January 2018

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Towards a small animal model for hepatitis C

21 January 2018

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Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors.

21 January 2018

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The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice

21 January 2018

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Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

21 January 2018

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Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis

21 January 2018

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Associations between hepatitis C viremia and low serum triglyceride and cholesterol levels: a community-based study

21 January 2018

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Critical role of PA28 in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis

21 January 2018

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HCV core protein induces hepatic lipid accumulation by activating SREBP1 and PPARgamma

21 January 2018

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Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

21 January 2018

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Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

21 January 2018

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Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: implications for HCV-associated hepatocarcinogenesis

21 January 2018

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Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C.

21 January 2018

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Oxidative stress EPR measurement in human liver by radical-probe technique. Correlation with etiology, histology and cell proliferation.

21 January 2018

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Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.

21 January 2018

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Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein

21 January 2018

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Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

21 January 2018

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Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3

21 January 2018

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The changing pattern of epidemiology in hepatocellular carcinoma

21 January 2018

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Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

21 January 2018

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HCV Tumor Promoting Effect Is Dependent on Host Genetic Background

21 January 2018

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DNA damage by oxygen-derived species Its mechanism and measurement in mammalian systems

21 January 2018

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Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

21 January 2018

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Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes

21 January 2018

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c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair.

21 January 2018

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Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein

21 January 2018

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Genomic instability--an evolving hallmark of cancer

21 January 2018

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Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression

21 January 2018

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Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest

21 January 2018

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Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein

21 January 2018

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

21 January 2018

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 January 2018

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Cell-cycle checkpoints and cancer

21 January 2018

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Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer.

21 January 2018

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Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein.

21 January 2018

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Calpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway

21 January 2018

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The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis

21 January 2018

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Risk factors for the rising rates of primary liver cancer in the United States.

21 January 2018

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Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EGH.11.14

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24 August 2017

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