(Q37887690)

24 August 2017

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title

Engineering antibiotic production and overcoming bacterial resistance (English)

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24 August 2017

main subject

antibiotic resistance

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Ioana Grigoras

3

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Anne-Gaëlle Planson

object named as

Anne-Gaëlle Planson

series ordinal

1

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Pablo Carbonell

object named as

Pablo Carbonell

series ordinal

2

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Jean-Loup Faulon

object named as

Jean-Loup Faulon

series ordinal

4

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publication date

10 June 2011

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24 August 2017

published in

Biotechnology Journal

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24 August 2017

volume

6

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24 August 2017

issue

7

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24 August 2017

page(s)

812-825

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Metabolic engineering of microorganisms: general strategies and drug production

24 August 2017

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

21 January 2018

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Combinatorial expression of bacterial whole mevalonate pathway for the production of beta-carotene in E. coli.

21 January 2018

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Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli

21 January 2018

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21 January 2018

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Synthetic biology for synthetic chemistry

21 January 2018

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Proteomic analysis of polyketide and nonribosomal peptide biosynthesis

21 January 2018

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The chemical versatility of natural-product assembly lines

21 January 2018

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Chapter 13. Nonribosomal peptide synthetases mechanistic and structural aspects of essential domains

21 January 2018

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Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms

21 January 2018

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An engineered yeast efficiently secreting penicillin

21 January 2018

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Staphylococcus aureus with Heterogeneous Resistance to Vancomycin: Epidemiology, Clinical Significance, and Critical Assessment of Diagnostic Methods

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Bromobalhimycin and chlorobromobalhimycins--illuminating the potential of halogenases in glycopeptide antibiotic biosyntheses

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Daptomycin, a bacterial lipopeptide synthesized by a nonribosomal machinery

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Comparative genome-scale metabolic reconstruction and flux balance analysis of multiple Staphylococcus aureus genomes identify novel antimicrobial drug targets

21 January 2018

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Blueprint for antimicrobial hit discovery targeting metabolic networks

21 January 2018

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21 January 2018

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Pathway discovery in metabolic networks by subgraph extraction

21 January 2018

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Inferring branching pathways in genome-scale metabolic networks

21 January 2018

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Properties of metabolic graphs: biological organization or representation artifacts?

21 January 2018

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PathPred: an enzyme-catalyzed metabolic pathway prediction server

21 January 2018

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The University of Minnesota Biocatalysis/Biodegradation Database: improving public access

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Route Designer: a retrosynthetic analysis tool utilizing automated retrosynthetic rule generation.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Exploring the diversity of complex metabolic networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Theoretical considerations and computational analysis of the complexity in polyketide synthesis pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Prediction of novel synthetic pathways for the production of desired chemicals

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Genome scale enzyme-metabolite and drug-target interaction predictions using the signature molecular descriptor.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Diversity of monomers in nonribosomal peptides: towards the prediction of origin and biological activity.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

NORINE: a database of nonribosomal peptides

21 January 2018

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Combinatorial biosynthesis for drug development

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Structure and mechanism of the 6-deoxyerythronolide B synthase

21 January 2018

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Revisiting the modularity of modular polyketide synthases

21 January 2018

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SBSPKS: structure based sequence analysis of polyketide synthases

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

MapsiDB: an integrated web database for type I polyketide synthases.

21 January 2018

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Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Computational analysis of phenotypic space in heterologous polyketide biosynthesis--applications to Escherichia coli, Bacillus subtilis, and Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Industrial systems biology

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Assembly of large genomic segments in artificial chromosomes by homologous recombination in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active entner-doudoroff pathway

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

21 January 2018

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Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Computational structure-based redesign of enzyme activity

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Bioassay-guided evolution of glycosylated macrolide antibiotics in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Synthetic protein scaffolds provide modular control over metabolic flux.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Environmentally controlled invasion of cancer cells by engineered bacteria

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.201100085

Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Outer membrane permeability and antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Three decades of beta-lactamase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Beta-lactams and beta-lactamase-inhibitors in current- or potential-clinical practice: a comprehensive update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Studies on amino acid replacement and inhibitory activity of a beta-lactamase inhibitory peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

How antibiotics kill bacteria: from targets to networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Dispersing biofilms with engineered enzymatic bacteriophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Bacteriophages as potential new therapeutics to replace or supplement antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Antimicrobial drug discovery through bacteriophage genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Tracking, tuning, and terminating microbial physiology using synthetic riboregulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Therapeutic applications of ribozymes and riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Bacterial charity work leads to population-wide resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

PathMiner: predicting metabolic pathways by heuristic search

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Finding metabolic pathways using atom tracking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Data-driven extraction of relative reasoning rules to limit combinatorial explosion in biodegradation pathway prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Rahnuma: hypergraph-based tool for metabolic pathway prediction and network comparison.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

Conformational Switches Modulate Protein Interactions in Peptide Antibiotic Synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100085

21 January 2018

Identifiers

DOI

10.1002/BIOT.201100085

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24 August 2017

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