(Q37893582)

24 August 2017

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title

Structural basis of thrombin-protease-activated receptor interactions (English)

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24 August 2017

Prafull S Gandhi

1

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24 August 2017

Zhiwei Chen

2

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24 August 2017

Eric Appelbaum

3

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24 August 2017

Fatima Zapata

4

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24 August 2017

Enrico Di Cera

5

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24 August 2017

publication date

1 June 2011

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24 August 2017

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24 August 2017

volume

63

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24 August 2017

issue

6

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24 August 2017

page(s)

375-382

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Platelet activation and atherothrombosis

24 August 2017

cites work

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Platelets: linking hemostasis and cancer

21 January 2018

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Cell biology. Beyond clotting: the powers of platelets

21 January 2018

1 reference

Basic principles of platelet biology and clinical implications

21 January 2018

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Platelet biology and implications for antiplatelet therapy in atherothrombotic disease

21 January 2018

1 reference

Thrombin and platelet activation

21 January 2018

1 reference

How the protease thrombin talks to cells

21 January 2018

1 reference

Thrombin signalling and protease-activated receptors

21 January 2018

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Protease-activated receptors in hemostasis, thrombosis and vascular biology

21 January 2018

1 reference

Central role of the P2Y12 receptor in platelet activation

21 January 2018

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Activation of platelet function through G protein-coupled receptors

21 January 2018

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Cell adhesion mechanisms in platelets

21 January 2018

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Protease-activated receptors in cardiovascular diseases

21 January 2018

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Role of thrombin signalling in platelets in haemostasis and thrombosis

21 January 2018

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Domains specifying thrombin–receptor interaction

21 January 2018

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Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

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A dual thrombin receptor system for platelet activation

21 January 2018

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PAR3 is a cofactor for PAR4 activation by thrombin

21 January 2018

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Cloning and characterization of human protease-activated receptor 4

21 January 2018

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Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin

21 January 2018

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Exosites in the substrate specificity of blood coagulation reactions

21 January 2018

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Engineering thrombin for selective specificity toward protein C and PAR1.

21 January 2018

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Functional mapping of the surface residues of human thrombin

21 January 2018

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Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

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Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C.

21 January 2018

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Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1

21 January 2018

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Structural identification of the pathway of long-range communication in an allosteric enzyme

21 January 2018

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Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4

21 January 2018

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Refined structure of the hirudin-thrombin complex

21 January 2018

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Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surface

21 January 2018

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Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage

21 January 2018

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Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex

21 January 2018

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Molecular dissection of Na+ binding to thrombin.

21 January 2018

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Serine protease mechanism and specificity

21 January 2018

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Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin

21 January 2018

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

21 January 2018

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Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site

21 January 2018

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Mutant N143P Reveals How Na+ Activates Thrombin

21 January 2018

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Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

21 January 2018

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The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin

21 January 2018

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Enhancing protein C interaction with thrombin results in a clot-activated anticoagulant

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.461

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24 August 2017

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