(Q37900363)

25 August 2017

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title

Genetic variants and the metabolic syndrome: a systematic review (English)

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25 August 2017

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4

E J M Feskens

1 reference

25 August 2017

C M Povel

1

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PubMed ID

21749608

25 August 2017

J M A Boer

series ordinal

2

1 reference

PubMed ID

21749608

25 August 2017

E Reiling

series ordinal

3

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25 August 2017

12 July 2011

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25 August 2017

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25 August 2017

12

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25 August 2017

11

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25 August 2017

952-967

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Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; Internat

25 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

"The Linosa Study": epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A navigator for human genome epidemiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association between 9p21 genomic markers and heart disease: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle-aged Swedish individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Measuring inconsistency in meta-analyses

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Lack of association between certain candidate gene polymorphisms and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Absence of Association of Metabolic Syndrome with PPARGC1A, PPARG and UCP1 Gene Polymorphisms in Asian Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Effects of two common polymorphisms of peroxisome proliferator-activated receptor-gamma gene on metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Interaction of DIO2 T92A and PPARgamma2 P12A polymorphisms in the modulation of metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of peroxisome proliferator-activated receptorgamma gene Pro12Ala and C161T polymorphisms with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Genetic variants associated with insulin resistance and metabolic syndrome in young Asian Indians with myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Relationship of PPARgamma2 polymorphism with obesity and metabolic syndrome in postmenopausal Polish women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor-gamma gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: interaction with smoking status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Prediction of genetic risk for metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association between peroxisome proliferator-activated receptor gamma haplotypes and the metabolic syndrome in French men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Polyunsaturated fatty acids modulate the effect of TCF7L2 gene variants on postprandial lipemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein A5 T-1131C variant confers risk for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

APOA5 variants and metabolic syndrome in Caucasians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Gender-modulated impact of apolipoprotein A5 gene (APOA5) -1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein A5 gene -1131T/C polymorphism is associated with the risk of metabolic syndrome in ethnic Chinese in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Metabolic syndrome in aboriginal Canadians: prevalence and genetic associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Lipid profiles and associated gene polymorphisms in young Asian Indian patients with acute myocardial infarction and the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein A-I positively associated with diabetes in women independently of apolipoprotein E genotype and apolipoprotein B levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The search for putative unifying genetic factors for components of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association between two common polymorphisms of PPARgamma gene and metabolic syndrome families in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Operating characteristics of a rank correlation test for publication bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Bias in meta-analysis detected by a simple, graphical test

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Apolipoprotein A5 IVS3+476A allelic variant associates with increased trigliceride levels and confers risk for development of metabolic syndrome in Hungarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Haplotype analysis of the apolipoprotein A5 gene in patients with the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

ApoCIII gene variants modulate postprandial response to both glucose and fat tolerance tests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

FTO: the first gene contributing to common forms of human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

FTO gene associates to metabolic syndrome in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of the FTO gene with obesity and the metabolic syndrome is independent of the IRS-2 gene in the female population of Southern France.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Effect of the -420C/G variant of the resistin gene promoter on metabolic syndrome, obesity, myocardial infarction and kidney dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The - 11391 G/A polymorphism of the adiponectin gene promoter is associated with metabolic syndrome traits and the outcome of an energy-restricted diet in obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Circulating high molecular weight adiponectin isoform is heritable and shares a common genetic background with insulin resistance in nondiabetic White Caucasians from Italy: evidence from a family-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

SNP276G>T polymorphism in the adiponectin gene is associated with metabolic syndrome in patients with type II diabetes mellitus in Korea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variation in the lamin A/C gene: associations with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The Gly16-->Arg16 and Gln27-->Glu27 polymorphisms of beta2-adrenergic receptor are associated with metabolic syndrome in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

No interactions between polymorphisms in the beta3-adrenergic receptor gene and the PPAR-gamma gene on the risk of the insulin resistance syndrome in the Danish MONICA cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

beta(3)-adrenergic receptor polymorphism and metabolic syndrome in postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Leptin Receptor Polymorphisms Interact with Polyunsaturated Fatty Acids to Augment Risk of Insulin Resistance and Metabolic Syndrome in Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association between the Gln223Arg polymorphism of the leptin receptor and metabolic syndrome in free-living community elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Genetics of leptin and obesity: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Features of the metabolic syndrome are modulated by an interaction between the peroxisome proliferator-activated receptor-delta -87T>C polymorphism and dietary fat in French-Canadians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

FABP2 Ala54Thr polymorphism and diabetes in Chilean elders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

UCP1 -3826 AG+GG genotypes, adiponectin, and leptin/adiponectin ratio in severe obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Uncoupling Protein 2 Promoter Polymorphism −866G/A, Central Adiposity, and Metabolic Syndrome in Asians*

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of the ins/del polymorphisms of uncoupling protein 2 (UCP2) with BMI in a Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Effect of the rs997509 polymorphism on the association between ectonucleotide pyrophosphatase phosphodiesterase 1 and metabolic syndrome and impaired glucose tolerance in childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Association of ENPP1 (PC-1) K121Q polymorphism with obesity-related parameters in subjects with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

The association of PC-1 (ENPP1) K121Q polymorphism with metabolic syndrome in patients with coronary heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Variable effects of the APOC3-482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Inflammation and metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

21 January 2018

The metabolic syndrome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Determinants of plasma apolipoprotein A-V and APOA5 gene transcripts in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Relationship between metabolic syndrome and Trp64arg polymorphism of the beta-adrenergic receptor gene in a general sample: the Shigaraki study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

Haplotype combination of Calpain-10 gene polymorphism is associated with metabolic syndrome in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00907.X

10.1111/J.1467-789X.2011.00907.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

21749608