(Q37900677)

25 August 2017

1 reference

title

New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin (English)

1 reference

25 August 2017

0 references

0 references

1 reference

Virginia Motilva

1

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25 August 2017

Sofía García-Mauriño

series ordinal

2

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25 August 2017

Elena Talero

series ordinal

3

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25 August 2017

Matilde Illanes

series ordinal

4

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25 August 2017

publication date

1 August 2011

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Journal of Pineal Research

25 August 2017

published in

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25 August 2017

volume

51

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25 August 2017

issue

1

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25 August 2017

page(s)

44-60

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News from the "5th International Meeting on Inflammatory Bowel Diseases" CAPRI 2010.

25 August 2017

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NF-kappaB signaling pathway, inflammation and colorectal cancer.

21 January 2018

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Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components

21 January 2018

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The role of T cell PPAR gamma in mice with experimental inflammatory bowel disease

21 January 2018

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CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD.

21 January 2018

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Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease

21 January 2018

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Rosiglitazone for active ulcerative colitis: a randomized placebo-controlled trial

21 January 2018

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ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells

21 January 2018

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Inflammatory bowel disease

21 January 2018

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Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum

21 January 2018

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Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis

21 January 2018

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Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress

21 January 2018

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Endoplasmic reticulum stress and intestinal inflammation

21 January 2018

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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Risk of malignant change in ulcerative colitis

21 January 2018

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Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

21 January 2018

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Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease

21 January 2018

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Recently identified and potential targets for colon cancer treatment.

21 January 2018

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Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis.

21 January 2018

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Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications.

21 January 2018

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The significance of aberrant crypt foci in understanding the pathogenesis of colon cancer

21 January 2018

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Inflammation and colon cancer

21 January 2018

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Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death

21 January 2018

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Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

21 January 2018

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21 January 2018

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21 January 2018

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Nf-kappa B, chemokine gene transcription and tumour growth

21 January 2018

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Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization.

21 January 2018

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Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NF-kappaB inhibitor DHMEQ.

21 January 2018

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Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potential

21 January 2018

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The nuclear hormone receptor PPARγ as a therapeutic target in major diseases.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Modulation of inflammatory changes in early stages of colon cancer through activation of PPARgamma by diclofenac

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Dietary conjugated linoleic acid and n-3 polyunsaturated fatty acids in inflammatory bowel disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

New issues about nitric oxide and its effects on the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

21 January 2018

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A systems biology viewpoint on autophagy in health and disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

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p53 and ARF: unexpected players in autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Autophagy regulation by p53.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Regulation of autophagy by cytoplasmic p53

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

21 January 2018

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Regulation of yeast sirtuins by NAD(+) metabolism and calorie restriction

21 January 2018

1 reference

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SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

"Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

21 January 2018

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Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare?

21 January 2018

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Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Resveratrol suppresses colitis and colon cancer associated with colitis

21 January 2018

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Taming the beast within: resveratrol suppresses colitis and prevents colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Function of the SIRT1 protein deacetylase in cancer

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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PCAF acetylates {beta}-catenin and improves its stability

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Ruminations on dietary restriction and aging.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Caloric restriction delays disease onset and mortality in rhesus monkeys

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Aging and cancer cell biology, 2009.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

The life span-prolonging effect of sirtuin-1 is mediated by autophagy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin protects against experimental reflux esophagitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin as an organoprotector in the stomach and the pancreas

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin: a pleiotropic molecule regulating inflammation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Clinical uses of melatonin: evaluation of human trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin: action as antioxidant and potential applications in human disease and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin reduces dinitrobenzene sulfonic acid-induced colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Change of nitric oxide in experimental colitis and its inhibition by melatonin in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin stimulates brain glutathione peroxidase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Regulation of antioxidant enzymes: a significant role for melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Protective effect of melatonin in acetic acid induced colitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin modulates signal transduction pathways and apoptosis in experimental colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Acutely administered melatonin is beneficial while chronic melatonin treatment aggravates the evolution of TNBS-induced colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin for ulcerative colitis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin triggers Crohn's disease symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin usage in ulcerative colitis: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

A Review of the Multiple Actions of Melatonin on the Immune System

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin induces apoptosis in human neuroblastoma cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin and celecoxib improve the outcomes in hamsters with experimental pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Basic mechanisms involved in the anti-cancer effects of melatonin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin: a multitasking molecule

21 January 2018

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The role of melatonin in immuno-enhancement: potential application in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Night-shift work and risk of colorectal cancer in the nurses' health study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

In vitro effects of melatonin on cell proliferation in a colon adenocarcinoma line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin and cell death: differential actions on apoptosis in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors

21 January 2018

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Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1).

21 January 2018

1 reference

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Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Possible involvement of the nuclear RZR/ROR-alpha receptor in the antitumor action of melatonin on murine Colon 38 cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Selective CCK-A but not CCK-B receptor antagonists inhibit HT-29 cell proliferation: synergism with pharmacological levels of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Autophagy: in sickness and in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

SIRT1 and p53, effect on cancer, senescence and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Autophagy upregulation and loss of NF-kappaB in oxidative stress-related immunodeficient SAMP8 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Could melatonin unbalance the equilibrium between autophagy and invasive processes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Ultrastructural clues for the protective effect of melatonin against oxidative damage in cerulein-induced pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin suppresses cyclosporine A-induced autophagy in rat pituitary GH3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Metabolism and cancer: the circadian clock connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Period 2 mutation accelerates ApcMin/+ tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Light at night, chronodisruption, melatonin suppression, and cancer risk: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin: a clock-output, a clock-input

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin plays a crucial role in the regulation of rhythmic clock gene expression in the mouse pars tuberalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Maternal melatonin effects on clock gene expression in a nonhuman primate fetus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

Resveratrol and rapamycin: are they anti-aging drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00915.X

10.1111/J.1600-079X.2011.00915.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference