(Q37902052)

25 August 2017

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title

The autophagic paradox in cancer therapy (English)

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25 August 2017

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W K K Wu

1

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25 August 2017

S B Coffelt

2

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25 August 2017

C H Cho

3

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25 August 2017

X J Wang

4

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25 August 2017

C W Lee

5

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25 August 2017

F K L Chan

6

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25 August 2017

J Yu

7

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25 August 2017

J J Y Sung

8

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25 August 2017

language of work or name

English

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publication date

18 July 2011

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25 August 2017

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25 August 2017

volume

31

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25 August 2017

issue

8

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25 August 2017

page(s)

939-953

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p53-Dependent and p53-independent activation of autophagy by ARF

25 August 2017

cites work

1 reference

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Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

21 January 2018

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ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

21 January 2018

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Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

21 January 2018

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Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis

21 January 2018

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Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways

21 January 2018

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The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

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The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis.

21 January 2018

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Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells

21 January 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

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Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

21 January 2018

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Akt induces apoptosis in neuroblastoma cells expressing a C98X vasopressin mutant following autophagy suppression.

21 January 2018

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Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model

21 January 2018

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Nuclear factor-kB, an unappreciated tumor suppressor

21 January 2018

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Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

21 January 2018

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p65/RelA modulates BECN1 transcription and autophagy

21 January 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

The IKK complex contributes to the induction of autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy-independent LC3 function in vesicular traffic.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

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Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

TGF-β1 Protects against Mesangial Cell Apoptosis via Induction of Autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.295

Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Rab7 Prevents Growth Factor-Independent Survival by Inhibiting Cell-Autonomous Nutrient Transporter Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Akt and autophagy cooperate to promote survival of drug-resistant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Induction of autophagy during extracellular matrix detachment promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Effect of IGF-1 on the balance between autophagy of dysfunctional mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

AMP-activated protein kinase: a universal regulator of autophagy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

NF-κB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

RB-E2F1: molecular rheostat for autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The RB-E2F1 pathway regulates autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The EphB2 tumor suppressor induces autophagic cell death via concomitant activation of the ERK1/2 and PI3K pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

NotI linking/jumping clones of human chromosome 3: mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy in cutaneous malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Stimulation of autophagy by the p53 target gene Sestrin2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Activation of autophagy during cell death requires the engulfment receptor Draper

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Mutant p53 protein localized in the cytoplasm inhibits autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Discovery of Atg5/Atg7-independent alternative macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy activation by NFkappaB is essential for cell survival after heat shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Bcl-xL and UVRAG cause a monomer-dimer switch in Beclin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The prognostic role of Beclin 1 protein expression in high-grade gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

E2F1 regulates autophagy and the transcription of autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Thiazolidinediones induce Rab7-RILP-MAPK-dependent juxtanuclear lysosome aggregation and reduce tumor cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

High-resolution characterization of a hepatocellular carcinoma genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Mitochondria get a Parkin' ticket

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Proteasome inhibition: a new therapeutic strategy to cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Pancreatic cancers require autophagy for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Oncogene-induced senescence pathways weave an intricate tapestry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

PUMA- and Bax-induced autophagy contributes to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy mediates the mitotic senescence transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Small molecule regulators of autophagy identified by an image-based high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

mTOR signaling pathway is a target for the treatment of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Autophagy facilitates oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Transcription of the RelB gene is regulated by NF-kappaB

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Relative down‐regulation of apoptosis and autophagy genes in colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Shikonin circumvents cancer drug resistance by induction of a necroptotic death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Light-chain 3A autophagic activity and prognostic significance in non-small cell lung carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Why do melanomas get so dark?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Regulation of autophagy by transforming growth factor-β (TGF-β) signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.295

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.295

1 reference

Dimensions Publication ID

25 August 2017

1033539706

0 references

1 reference