(Q37902643)

25 August 2017

1 reference

title

Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and Alzheimer's disease (English)

1 reference

25 August 2017

0 references

0 references

Garth J S Cooper

1

1 reference

25 August 2017

1 July 2011

1 reference

25 August 2017

1 reference

25 August 2017

71

1 reference

25 August 2017

1281-1320

1 reference

25 August 2017

10

1 reference

https://scigraph.springernature.com/pub.10.2165/11591370-000000000-00000

25 August 2017

0 references

cites work

Protein glycation and oxidative stress in diabetes mellitus and ageing

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Transition metals redox: reviving an old plot for diabetic vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Ageing and neuronal vulnerability

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Oxidative stress as a major culprit in kidney disease in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Mechanisms of neurodegeneration in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Increased risk of type 2 diabetes in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Fas-associated death receptor signaling evoked by human amylin in islet beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

TGF-beta: regulation of extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

TGF-beta and fibrosis in different organs - molecular pathway imprints

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Nonenzymatic glycosylation and the pathogenesis of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Prevention and repair of protein damage by the Maillard reaction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Glycochelates and the etiology of diabetic peripheral neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Interactions of copper with glycated proteins: possible involvement in the etiology of diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A copper chelating agent suppresses carbonyl stress in diabetic rat lenses

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Metal complexation by the peptide-bound maillard reaction products N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The pathobiology of diabetic complications: a unifying mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Regeneration of the heart in diabetes by selective copper chelation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Demonstration of a hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation: quantitative comparisons between the biology of copper and eight other nutritionally essential elements in

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Global prevalence of dementia: a Delphi consensus study

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Demonstrating the case that AD is a vascular disease: epidemiologic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Status of risk factors for vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Glucose control and vascular complications in veterans with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effects of intensive glucose lowering in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

10-year follow-up of intensive glucose control in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effect of a multifactorial intervention on mortality in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Management of diabetic retinopathy: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper(II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-beta activation in the kidneys of rats used as a model of diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effects of an extracellular metal chelator on neurovascular function in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effects of trientine, a metal chelator, on defective endothelium-dependent relaxation in the mesenteric vasculature of diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cardiovascular effects of dietary copper deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Homozygosity (E140K) in SCO2 causes delayed infantile onset of cardiomyopathy and neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Mutations in SCO2 are associated with a distinct form of hypertrophic cardiomyopathy and cytochrome c oxidase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cytochrome c oxidase deficiency due to mutations in SCO2, encoding a mitochondrial copper-binding protein, is rescued by copper in human myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The possible role of copper ions in atherogenesis: the Blue Janus

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Transition Metal Speciation in the Cell: Insights from the Chemistry of Metal Ion Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Function, structure, and mechanism of intracellular copper trafficking proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper chaperone for Cu/Zn superoxide dismutase is a sensitive biomarker of mild copper deficiency induced by moderately high intakes of zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Function and regulation of human copper-transporting ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper is taken up efficiently from albumin and alpha2-macroglobulin by cultured human cells by more than one mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Transcuprein is a macroglobulin regulated by copper and iron availability

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Hepatic iron overload in aceruloplasminaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Ceruloplasmin metabolism and function

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The copper-iron connection: hereditary aceruloplasminemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Observations on the anemia and neutropenia of human copper deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Rat embryos cultured under copper-deficient conditions develop abnormally and are characterized by an impaired oxidant defense system

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Low nitric oxide: a key factor underlying copper-deficiency teratogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

D-penicillamine-induced copper deficiency in suckling mice: neurological abnormalities and brain mitochondrial enzyme activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cerebral oedema in lambs associated with hypocuprosis, and its relationship to swayback. I. Field, clinical, gross anatomical and biochemical observations

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Aspects of cardiomyopathy in copper-deficient pigs. Electrocardiography, echocardiography, and ultrastructural findings.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Metallothionein is crucial for safe intracellular copper storage and cell survival at normal and supra-physiological exposure levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper deficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Skeletal changes of copper deficiency in infants receiving prolonged total parenteral nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper deficiency in long-term parenteral nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper deficiency in the preterm infant of very low birthweight. Four cases and a reference range for plasma copper

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Alterations in copper and collagen metabolism in Menkes' syndrome and a new subtype of Ehlers-Danlos syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper, oxidative stress, and human health

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Endemic Tyrolean infantile cirrhosis is not an allelic variant of Wilson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Zinc acetate for the treatment of Wilson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Animal models of copper-associated liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

ACE1, a copper-dependent transcription factor, activates expression of the yeast copper, zinc superoxide dismutase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The interaction of nitric oxide (NO) with the yeast transcription factor Ace1: A model system for NO-protein thiol interactions with implications to metal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Regulation of aortic CuZn-superoxide dismutase with copper. Caeruloplasmin and albumin re-activate and transfer copper to the enzyme in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Regulation of aortic CuZn-superoxide dismutase with copper. Effects in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Treatment of Wilson's disease with trientine (triethylene tetramine) dihydrochloride

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Mode of action of triethylenetetramine dihydrochloride on copper metabolism in Wilson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Pharmacokinetic and pharmacodynamic modeling of a copper-selective chelator (TETA) in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Prediction of creatinine clearance from serum creatinine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Reversal of diabetes-evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)-selective chelator

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Pharmacokinetics, pharmacodynamics, and metabolism of triethylenetetramine in healthy human participants: an open-label trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Development and validation of a rapid HPLC method for the simultaneous determination of triethylenetetramine and its two main metabolites in human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

21 January 2018

Polyamine homoeostasis

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Expert consensus document on arterial stiffness: methodological issues and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function?

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effect of long-term type 1 diabetes on renal sodium and water transporters in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Roles of aquaporins in kidney revealed by transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Molecular changes in proximal tubule function in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Acute copper sulphate poisoning: a case report and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Transition metals and polyol pathway in the development of diabetic neuropathy in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effect of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper, Zinc, Manganese, and Magnesium Status and Complications of Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The role of metal-catalyzed oxidation in the formation of advanced glycation end products: an in vitro study on collagen.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A population-based study of dementia in 85-year-olds.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

A drastic reduction in the life span of cystatin C L68Q carriers due to life-style changes during the last two centuries

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Coordination of copper(II) ions by the 11-20 and 11-28 fragments of human and mouse beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cu(II) interaction with amyloid-beta peptide: a review of neuroactive mechanisms in AD brains

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Elevation of serum copper levels in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Red blood cell copper, zinc superoxide dismutase activity is higher in Alzheimer's disease and is decreased by D-penicillamine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The possible role of capillary cerebral amyloid angiopathy in Alzheimer lesion development: a regional comparison.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Prevalence and impact of cerebrovascular lesions in Alzheimer and lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Alzheimer's disease pathology influences severity and topographical distribution of cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Amyloid beta peptide 1-42 highly correlates with capillary cerebral amyloid angiopathy and Alzheimer disease pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Only cerebral capillary amyloid angiopathy correlates with Alzheimer pathology--a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Computer-assisted three-dimensional image analysis of cerebral amyloid angiopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The galvanization of beta-amyloid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The metallobiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Agents complexing copper as a therapeutic strategy for the treatment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Metal complexing agents as therapies for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The risks of free copper in the body and the development of useful anticopper drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

The curious case of clioquinol

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Stoichiometry and conditional stability constants of Cu(II) or Zn(II) clioquinol complexes; implications for Alzheimer's and Huntington's disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Impaired endothelium-dependent vasodilatation in women with previous gestational diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Effect of valsartan on the incidence of diabetes and cardiovascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cerebrovascular damage in late-life depression is associated with structural and functional abnormalities of subcutaneous small arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Acquired sideroblastic anaemia during treatment of Wilson's disease with triethylene tetramine dihydrochloride

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Structure, properties, and function of a copper(I)-copper(II) complex of D-penicillamine: pentathallium(I) mu8-chloro-dodeca (D-penicillaminato)-octacuprate(I)hexacuprate(II) n-hydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Cerebral microbleeds in the population based AGES-Reykjavik study: prevalence and location

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

Demyelination in Lambs Born of Ewes Maintained on High Intakes of Sulphate and Molybdate

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11591370-000000000-00000

SWAYBACK: A DEMYELINATING DISEASE OF LAMBS WITH AFFINITIES TO SCHILDER'S ENCEPHALITIS AND ITS PREVENTION BY COPPER.

21 January 2018

1 reference

12 December 2020

Crystal and molecular structure of bis(copper(II) D-penicillamine disulfide) nonahydrate, a derivative of copper(II) cystinate

1 reference

12 December 2020

Mechanisms of tolerance in the copper-loaded rat liver

1 reference

12 December 2020

Metabolism of administered triethylene tetramine dihydrochloride in humans

1 reference

12 December 2020

Manifestations of copper excess

1 reference

12 December 2020

An in vitro study on the role of metal catalyzed oxidation in glycation and crosslinking of collagen

1 reference

12 December 2020

Acute copper sulfate poisoning

1 reference

12 December 2020

Copper status of young men consuming a low-copper diet

1 reference

12 December 2020

Clinical manifestations of nutritional copper deficiency in infants and children

1 reference

12 December 2020

Cardiac hypertrophy in copper-deficient rats is owing to increased mitochondria

1 reference

12 December 2020

Treatment of Wilson's disease with zinc: X. Intestinal metallothionein induction

1 reference

12 December 2020

Role of copper in Indian childhood cirrhosis

1 reference

12 December 2020

Transition metals bind to glycated proteins forming redox active "glycochelates": implications for the pathogenesis of certain diabetic complications

1 reference

12 December 2020

Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men.

1 reference

12 December 2020

A delicate balance: homeostatic control of copper uptake and distribution

1 reference

12 December 2020

Illuminating the molecular basis of diabetic arteriopathy: A proteomic comparison of aortic tissue from diabetic and healthy rats

1 reference

12 December 2020

CARDIOVASCULAR STUDIES ON COPPER-DEFICIENT SWINE. IV. CONTENT AND SOLUBILITY OF THE AORTIC ELASTIN, COLLAGEN, AND HEXOSAMINE

1 reference

12 December 2020

Is type 2 diabetes an amyloidosis and does it really matter (to patients)?

1 reference

12 December 2020

THE QUESTION OF COPPER DEFICIENCY IN MAN.

1 reference

12 December 2020

Effects of chelator treatment on aorta and corpus cavernosum from diabetic rats

1 reference

12 December 2020

Proteomic analysis of the brain in Alzheimer’s disease: Molecular phenotype of a complex disease process

1 reference

12 December 2020

The Wilson disease gene: spectrum of mutations and their consequences.

1 reference

12 December 2020

Serum and urinary magnesium, calcium and copper levels in insulin-dependent diabetic women.

1 reference

12 December 2020

Clinical determinants of dememtia related to stroke

1 reference

12 December 2020

Copper biochemistry and molecular biology

1 reference

12 December 2020

Oxidative stress in Huntington's disease

1 reference

12 December 2020

Characterization of proteomic changes in cardiac mitochondria in streptozotocin-diabetic rats using iTRAQ™ isobaric tags

1 reference

12 December 2020

Copper in diseases and treatments, and copper-based anticancer strategies.

1 reference

12 December 2020

Cardiovascular studies on copper-deficient swine. II. Mechanical properties of the aorta

1 reference

12 December 2020

The 'mysterious' disease in Swedish moose. Concentrations of trace elements in liver and kidneys and clinical chemistry. Comparison with experimental molybdenosis and copper deficiency in the goat

1 reference

12 December 2020

Copper absorption, excretion, and retention by young men consuming low dietary copper determined by using the stable isotope 65Cu

1 reference

12 December 2020

Vascular factors and Alzheimer disease

1 reference

12 December 2020

Long-term treatment of Wilson's disease with triethylene tetramine dihydrochloride (trientine)

1 reference

12 December 2020

Wilson's Disease Treatment by Triethylene Tetramine Dihydrochloride (Trientine, 2HCI): Long-Term Observations

1 reference

12 December 2020

Molecular Changes Evoked by Triethylenetetramine Treatment in the Extracellular Matrix of the Heart and Aorta in Diabetic Rats

1 reference

12 December 2020

Mechanisms for protection against copper toxicity

1 reference

12 December 2020

Effects of combination lipid therapy in type 2 diabetes mellitus

1 reference

12 December 2020

Induction of increased collagen and elastin biosynthesis in copper-deficient pig aorta

1 reference

12 December 2020

Cardiac Wilson's disease

1 reference

12 December 2020

Transition metal-mediated glycoxidation accelerates cross-linking of beta-amyloid peptide

1 reference

12 December 2020

Drug development based on the metals hypothesis of Alzheimer's disease

1 reference

12 December 2020

Idiopathic copper toxicosis

1 reference

12 December 2020

In vivo evidence of hydroxyl radical formation after acute copper and ascorbic acid intake: electron spin resonance spin-trapping investigation

1 reference

12 December 2020

Swayback (enzootic ataxia) in Alberta lambs.

1 reference

12 December 2020

Vitamin E supplementation and cardiovascular events in high-risk patients

1 reference

12 December 2020

Protein Aging by Carboxymethylation of Lysines Generates Sites for Divalent Metal and Redox Active Copper Binding: Relevance to Diseases of Glycoxidative Stress

1 reference

12 December 2020

"Glycated hemoglobin," not "glycosylated" or "glucosylated"

1 reference

12 December 2020

Urinary copper excretion in type 2 diabetic patients with nephropathy

1 reference

12 December 2020

Indian childhood cirrhosis: several dilemmas resolved

1 reference

12 December 2020

Experimental copper and chromium deficiency and additional molybdenum supplementation in goats. II. Concentrations of trace and minor elements in liver, kidneys and ribs: haematology and clinical chemistry

1 reference

12 December 2020

Basic and clinical aspects of copper

1 reference

12 December 2020

Copper depletion and deficiency in the malnourished infant

1 reference

12 December 2020

Cerebral amyloid angiopathy in Lewy body disease

1 reference

12 December 2020

Endemic Tyrolean infantile cirrhosis: an ecogenetic disorder

1 reference

12 December 2020

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

1 reference

12 December 2020

A randomized trial of copper therapy in rats with electrocardiographic abnormalities due to copper deficiency

1 reference

12 December 2020

Changes in the collagen of rat heart in copper-deficiency-induced cardiac hypertrophy

1 reference

12 December 2020

NaFe3+EDTA as a food fortificant: influence on zinc, calcium and copper metabolism in the rat

1 reference

12 December 2020

Copper deficiency complicating severe chronic intestinal malabsorption

1 reference

12 December 2020

Copper chelation in patients with Wilson's disease. A comparison of penicillamine and triethylene tetramine dihydrochloride

1 reference

12 December 2020

Experimental chronic copper toxicity in sheep. Histological and histochemical changes during the development of the lesions in the liver.

1 reference

12 December 2020

'Mysterious' moose disease in Sweden. Similarities to copper deficiency and/or molybdenosis in cattle and sheep. Biochemical background of clinical signs and organ lesions

1 reference

12 December 2020

CARDIOVASCULAR STUDIES ON COPPER-DEFICIENT SWINE. VI. THE MUCOPOLYSACCHARIDE COMPOSITION OF AORTA AND CARTILAGE

1 reference

12 December 2020

Cellular mechanisms of toxicity and tolerance in the copper-loaded rat. II. Pathogenesis of copper toxicity in the liver

1 reference

12 December 2020

Neutropenia caused by copper deficiency: possible mechanisms of action.

1 reference

12 December 2020

Metallothionein inhibits myocardial apoptosis in copper-deficient mice: role of atrial natriuretic peptide

1 reference

12 December 2020

1 reference

12 December 2020

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

12 December 2020

Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications

1 reference

12 December 2020

Copper absorption and retention in young men at three levels of dietary copper by use of the stable isotope 65Cu

1 reference

12 December 2020

Experimental chronic copper toxicity in sheep. Biochemical and haematological studies during the development of lesions in the liver

1 reference

12 December 2020

A Conspectus of Research on Copper Metabolism and Requirements of Man

1 reference

12 December 2020

Long-term high copper intake: effects on copper absorption, retention, and homeostasis in men.

1 reference

12 December 2020

Indications of copper deficiency in a subpopulation of Alaskan moose.

1 reference

12 December 2020

Ceruloplasmin (2-D PAGE) Pattern and Copper Content in Serum and Brain of Alzheimer Disease Patients

1 reference

12 December 2020

Copper deficiency and cardiovascular disease: role of peroxidation, glycation, and nitration

1 reference

12 December 2020

Physiological and metabolic characterization of a cardiomyopathy induced by chronic copper deficiency

1 reference

12 December 2020

Alterations in hypertrophic gene expression by dietary copper restriction in mouse heart

1 reference

12 December 2020

Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients

1 reference

12 December 2020

Atrial thrombosis, abnormal electrocardiograms and sudden death in mice due to copper deficiency

1 reference

12 December 2020

Teratogenesis and low copper status resulting from D-penicillamine in rats

1 reference

12 December 2020

A syndrome of molybdenosis, copper deficiency, and type 2 diabetes in the moose population of south-west Sweden

1 reference

12 December 2020

Hepatic iron concentration combined with long-term monitoring of serum ferritin to predict complications of iron overload in thalassaemia major

1 reference

12 December 2020

Identification of N epsilon- carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

1 reference

12 December 2020

The metal chelators, trientine and citrate, inhibit the development of cardiac pathology in the Zucker diabetic rat.

1 reference

12 December 2020

Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer's disease. Pro-CAA position statement.

1 reference

12 December 2020

Use and misuse of balance studies

1 reference

12 December 2020

Copper deficiency and copper toxicity in the rat

1 reference

12 December 2020

Regression of dietary copper restriction-induced cardiomyopathy by copper repletion in mice

1 reference

12 December 2020

10.2165/11591370-000000000-00000

Identifiers

DOI

1 reference

PubMed ID

21770477

Dimensions Publication ID

25 August 2017

0 references

1 reference

PubMed ID

21770477