(Q37903853)

25 August 2017

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title

Current understanding of insulin resistance in hepatitis C. (English)

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25 August 2017

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Vincent Kaddai

1

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PubMed ID

21780897

25 August 2017

Francesco Negro

series ordinal

2

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25 August 2017

1 August 2011

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Expert Review of Gastroenterology & Hepatology

25 August 2017

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25 August 2017

5

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25 August 2017

4

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25 August 2017

503-516

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Evolving epidemiology of hepatitis C virus

25 August 2017

1 reference

Review article: chronic hepatitis C--natural history and cofactors

21 January 2018

1 reference

STEATOSIS IN CHRONIC HEPATITIS C: WHY DOES IT REALLY MATTER?

21 January 2018

1 reference

Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data.

21 January 2018

1 reference

Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected].

21 January 2018

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Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population

21 January 2018

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Association of diabetes mellitus and chronic hepatitis C virus infection.

21 January 2018

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Prevalence of diabetes mellitus in patients with end-stage liver cirrhosis due to hepatitis C, alcohol, or cholestatic disease.

21 January 2018

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Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users

21 January 2018

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High prevalence of glucose abnormalities in patients with hepatitis C virus infection: a multivariate analysis considering the liver injury

21 January 2018

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Prevalence of diabetes mellitus and insulin resistance in patients with chronic hepatitis C: comparison with hepatitis B virus-infected and hepatitis C virus-cleared patients

21 January 2018

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Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection

21 January 2018

1 reference

Prevalence of diabetes mellitus in renal transplant patients with hepatitis B or C virus infection

21 January 2018

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Hepatitis C virus infection: evidence for an association with type 2 diabetes

21 January 2018

1 reference

Reappraisal of the characteristics of glucose abnormalities in patients with chronic hepatitis C infection

21 January 2018

1 reference

Chronic hepatitis C and type II diabetes mellitus: a prospective cross-sectional study

21 January 2018

1 reference

High prevalence of hepatitis C infection in Afro-Caribbean patients with type 2 diabetes and abnormal liver function tests.

21 January 2018

1 reference

Low prevalence of hepatitis C virus infection in Greek diabetic patients

21 January 2018

1 reference

Hepatitis C virus and atherosclerosis in patients with type 2 diabetes

21 January 2018

1 reference

Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States

21 January 2018

1 reference

Hepatitis C virus infection and incident type 2 diabetes

21 January 2018

1 reference

Hepatitis C virus infection and the development of type 2 diabetes in a community-based longitudinal study

21 January 2018

1 reference

Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis

21 January 2018

1 reference

New onset diabetes mellitus after liver transplantation and hepatitis C virus infection: meta-analysis of clinical studies

21 January 2018

1 reference

Insulin resistance: a metabolic pathway to chronic liver disease

21 January 2018

1 reference

Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis

21 January 2018

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Insulin resistance is associated with liver fibrosis in non-diabetic chronic hepatitis C patients

21 January 2018

1 reference

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C.

21 January 2018

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Correlation between insulin resistance and hepatitis C viral load

21 January 2018

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High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C.

21 January 2018

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Hepatitis C virus directly associates with insulin resistance independent of the visceral fat area in nonobese and nondiabetic patients

21 January 2018

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Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.

21 January 2018

1 reference

Impact of amino acid substitutions in hepatitis C virus genotype 1b core region on liver steatosis and glucose tolerance in non-cirrhotic patients without overt diabetes

21 January 2018

1 reference

Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.

21 January 2018

1 reference

Risk factors for the development of diabetes mellitus in chronic hepatitis C virus genotype 4 infection.

21 January 2018

1 reference

Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C.

21 January 2018

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Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C.

21 January 2018

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Sustained virological response correlates with reduction in the incidence of glucose abnormalities in patients with chronic hepatitis C virus infection.

21 January 2018

1 reference

Incidence of type 2 diabetes mellitus and glucose abnormalities in patients with chronic hepatitis C infection by response to treatment: results of a cohort study

21 January 2018

1 reference

Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C.

21 January 2018

1 reference

Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial

21 January 2018

1 reference

The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2

21 January 2018

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Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C.

21 January 2018

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Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance.

21 January 2018

1 reference

Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

21 January 2018

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Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3

21 January 2018

1 reference

The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms

21 January 2018

1 reference

Attenuation of leptin and insulin signaling by SOCS proteins

21 January 2018

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A complex interplay between Akt, TSC2 and the two mTOR complexes

21 January 2018

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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

21 January 2018

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Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance

21 January 2018

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Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.

21 January 2018

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Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C.

21 January 2018

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Upregulation of protein phosphatase 2Ac by hepatitis C virus modulates NS3 helicase activity through inhibition of protein arginine methyltransferase 1.

21 January 2018

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Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

21 January 2018

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Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A.

21 January 2018

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Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3.

21 January 2018

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Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activation

21 January 2018

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Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication

21 January 2018

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Distribution of markers of hepatitis C virus infection throughout the body

21 January 2018

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Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein

21 January 2018

1 reference

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

21 January 2018

1 reference

Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study

21 January 2018

1 reference

Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system

21 January 2018

1 reference

Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters

21 January 2018

1 reference

Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis

21 January 2018

1 reference

Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway

21 January 2018

1 reference

Elevated levels of interleukin-18 predict the development of type 2 diabetes: results from the MONICA/KORA Augsburg Study, 1984-2002.

21 January 2018

1 reference

Interleukin-1beta induces the novel adipokine chemerin in adipocytes in vitro

21 January 2018

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Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells.

21 January 2018

1 reference

Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels, and atherosclerosis in LDL receptor knockout mice on high-fat diet

21 January 2018

1 reference

Fibrogenic impact of high serum glucose in chronic hepatitis C.

21 January 2018

1 reference

In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy.

21 January 2018

1 reference

Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy

21 January 2018

1 reference

Fibrosis in genotype 3 chronic hepatitis C and nonalcoholic fatty liver disease: Role of insulin resistance and hepatic steatosis

21 January 2018

1 reference

Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus

21 January 2018

1 reference

Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C.

21 January 2018

1 reference

The impact of diabetes mellitus on fibrosis progression in patients transplanted for hepatitis C.

21 January 2018

1 reference

Impact of diabetes and hepatitis after kidney transplantation on patients who are affected by hepatitis C virus

21 January 2018

1 reference

High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis

21 January 2018

1 reference

Connective tissue growth factor, steatosis and fibrosis in patients with chronic hepatitis C.

21 January 2018

1 reference

Pathogenesis of liver fibrosis

21 January 2018

1 reference

Chemokines in the immunopathogenesis of hepatitis C infection

21 January 2018

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Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines

21 January 2018

1 reference

The impact of insulin resistance, serum adipocytokines and visceral obesity on steatosis and fibrosis in patients with chronic hepatitis C.

21 January 2018

1 reference

Serum adipokine levels in chronic liver diseases: association of resistin levels with fibrosis severity.

21 January 2018

1 reference

Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure.

21 January 2018

1 reference

Liver fibrosis in women with chronic hepatitis C: evidence for the negative role of the menopause and steatosis and the potential benefit of hormone replacement therapy

21 January 2018

1 reference

Early menopause is associated with lack of response to antiviral therapy in women with chronic hepatitis C.

21 January 2018

1 reference

Glucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overload.

21 January 2018

1 reference

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury

21 January 2018

1 reference

Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study

21 January 2018

1 reference

Abnormalities of lipid metabolism in hepatitis C virus infection

21 January 2018

1 reference

Hepatitis C virus induced hypobetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C.

21 January 2018

1 reference

Hepatocellular fat accumulation and low serum cholesterol in patients infected with HCV-3a

21 January 2018

1 reference

Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up

21 January 2018

1 reference

Hepatitis B and C virus infection and the risk of atherosclerosis in a general population

21 January 2018

1 reference

Hepatitis C infection and clearance: impact on atherosclerosis and cardiometabolic risk factors

21 January 2018

1 reference

Risk factors and consequences of post-transplant diabetes mellitus.

21 January 2018

1 reference

Components of metabolic syndrome are independent predictors of mortality in patients with chronic liver disease: a population-based study

21 January 2018

1 reference

Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

21 January 2018

1 reference

Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.

21 January 2018

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Insulin resistance and geographical origin: major predictors of liver fibrosis and response to peginterferon and ribavirin in HCV-4.

21 January 2018

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Insulin resistance predicts response to peginterferon-alpha/ribavirin combination therapy in chronic hepatitis C patients.

21 January 2018

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Insulin resistance is a major determinant of sustained virological response in genotype 1 chronic hepatitis C patients receiving peginterferon alpha-2b plus ribavirin.

21 January 2018

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Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load.

21 January 2018

1 reference

Insulin resistance predicts rapid virologic response to peginterferon/ribavirin combination therapy in hepatitis C genotype 4 patients

21 January 2018

1 reference

Race, insulin resistance and hepatic steatosis in chronic hepatitis C.

21 January 2018

1 reference

Insulin resistance impairs sustained virological response rate to pegylated interferon plus ribavirin in HIV-hepatitis C virus-coinfected patients: HOMAVIC-ANRS HC02 Study

21 January 2018

1 reference

Insulin resistance impairs response to interferon plus ribavirin in patients coinfected with HIV and hepatitis C virus

21 January 2018

1 reference

Insulin resistance impairs rapid virologic response in HIV/hepatitis C virus coinfected patients on peginterferon-alfa-2a

21 January 2018

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Insulin resistance affects early virologic response in HIV-infected subjects treated for hepatitis C infection

21 January 2018

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Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin

21 January 2018

1 reference

Early prediction of sustained virological response at day 3 of treatment with albinterferon-alpha-2b in patients with genotype 2/3 chronic hepatitis C.

21 January 2018

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Correlates and prognostic value of the first-phase hepatitis C virus RNA kinetics during treatment.

21 January 2018

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Clinical trial: low plasma cholesterol and oxidative stress predict rapid virological response to standard therapy with peginterferon and ribavirin in HCV patients.

21 January 2018

1 reference

Insulin resistance is not a relevant predictor of sustained virological response to pegylated interferon plus ribavirin in HIV/HCV co-infected patients

21 January 2018

1 reference

Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy

21 January 2018

1 reference

Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1

21 January 2018

1 reference

Signaling by type I and II cytokine receptors: ten years after

21 January 2018

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Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C.

21 January 2018

1 reference

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

21 January 2018

1 reference

The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial

21 January 2018

1 reference

Effect of iron depletion on serum markers of fibrogenesis, oxidative stress and serum liver enzymes in chronic hepatitis C: results of a pilot study

21 January 2018

1 reference

Long-term phlebotomy with low-iron diet therapy lowers risk of development of hepatocellular carcinoma from chronic hepatitis C.

21 January 2018

1 reference

Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease

21 January 2018

1 reference

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease

21 January 2018

1 reference

Association of exogenous insulin or sulphonylurea treatment with an increased incidence of hepatoma in patients with hepatitis C virus infection

21 January 2018

1 reference

Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin

21 January 2018

1 reference

Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin

21 January 2018

1 reference

Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance

21 January 2018

1 reference

Hepatitis C Viremia Increases the Association With Type 2 Diabetes Mellitus in a Hepatitis B and C Endemic Area: An Epidemiological Link With Virological Implication

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EGH.11.43

1 reference

release_4b33iurqojcexcpodhj32j3yqi

25 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/4b33iurqojcexcpodhj32j3yqi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

21780897

1 reference

PubMed ID

21780897