(Q37905033)

25 August 2017

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title

Transporter-mediated drug-drug interactions. (English)

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25 August 2017

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Fabian Müller

1

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PubMed ID

21787191

25 August 2017

Martin F Fromm

series ordinal

2

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25 August 2017

1 July 2011

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25 August 2017

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25 August 2017

12

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25 August 2017

1017-1037

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25 August 2017

7

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Transporters and drug therapy: implications for drug disposition and disease

25 August 2017

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Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

21 January 2018

1 reference

Potent inhibition of human cytochrome P450 3A4, 2D6, and 2C9 isoenzymes by grapefruit juice and its furocoumarins.

21 January 2018

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Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

21 January 2018

1 reference

Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver

21 January 2018

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Intestinal drug transporter expression and the impact of grapefruit juice in humans

21 January 2018

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Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

21 January 2018

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Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans

21 January 2018

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The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.

21 January 2018

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Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol

21 January 2018

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Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol

21 January 2018

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Effects of orange juice on the pharmacokinetics of atenolol

21 January 2018

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Absorption, Distribution, Metabolism, and Elimination of the Direct Renin Inhibitor Aliskiren in Healthy Volunteers

21 January 2018

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Clinical pharmacokinetics and pharmacodynamics of aliskiren

21 January 2018

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Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren

21 January 2018

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Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren

21 January 2018

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Rifampicin reduces the plasma concentrations and the renin-inhibiting effect of aliskiren

21 January 2018

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Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskiren

21 January 2018

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Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition

21 January 2018

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Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.

21 January 2018

1 reference

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

21 January 2018

1 reference

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

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P-glycoprotein-mediated intestinal and biliary digoxin transport in humans

21 January 2018

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Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 January 2018

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Importance of P-glycoprotein at blood-tissue barriers

21 January 2018

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The drug transporter-metabolism alliance: uncovering and defining the interplay

21 January 2018

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Metabolism of digoxin, digoxigenin digitoxosides and digoxigenin in human hepatocytes and liver microsomes

21 January 2018

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Digoxin in the management of cardiovascular disorders

21 January 2018

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The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin

21 January 2018

1 reference

Genetic Influences on the Pharmacokinetics of Orally and Intravenously Administered Digoxin as Exhibited by Monozygotic Twins

21 January 2018

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Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug

21 January 2018

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Membrane transporters in drug development

21 January 2018

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Importance of P-glycoprotein for drug-drug interactions

21 January 2018

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

21 January 2018

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Human intestinal P-glycoprotein activity estimated by the model substrate digoxin

21 January 2018

1 reference

Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics

21 January 2018

1 reference

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

1 reference

Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design.

21 January 2018

1 reference

Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells

21 January 2018

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Potentiation of pirarubicin activity in multidrug resistant cells by rifampicin.

21 January 2018

1 reference

Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

21 January 2018

1 reference

Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies

21 January 2018

1 reference

Inhibition of P-glycoprotein-mediated efflux of digoxin and its metabolites by macrolide antibiotics.

21 January 2018

1 reference

Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction

21 January 2018

1 reference

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

21 January 2018

1 reference

The effect of age upon liver volume and apparent liver blood flow in healthy man.

21 January 2018

1 reference

Hepatic vascular flow measurements by phase contrast MRI and doppler echography: a comparative and reproducibility study.

21 January 2018

1 reference

Direct measurement of hepatic blood flow during living donor liver transplantation in children

21 January 2018

1 reference

Hepatic perfusion before and after the transjugular intrahepatic portosystemic shunt procedure: impact on survival

21 January 2018

1 reference

Clinical application of hepatic CT perfusion

21 January 2018

1 reference

Effect of rosuvastatin therapy on coronary artery stenoses assessed by quantitative coronary angiography: a study to evaluate the effect of rosuvastatin on intravascular ultrasound-derived coronary atheroma burden.

21 January 2018

1 reference

Long-term efficacy and safety of rosuvastatin 40 mg in patients with severe hypercholesterolemia.

21 January 2018

1 reference

Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database

21 January 2018

1 reference

Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs

21 January 2018

1 reference

Muscle toxicity with statins

21 January 2018

1 reference

No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin

21 January 2018

1 reference

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms

21 January 2018

1 reference

The SLCO1B1*5 genetic variant is associated with statin-induced side effects

21 January 2018

1 reference

SLCO1B1 variants and statin-induced myopathy--a genomewide study

21 January 2018

1 reference

Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction

21 January 2018

1 reference

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

21 January 2018

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The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.

21 January 2018

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Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin

21 January 2018

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Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

21 January 2018

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Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide

21 January 2018

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Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.

21 January 2018

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21 January 2018

Bile acid transporters

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Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1.

21 January 2018

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Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

21 January 2018

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Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

21 January 2018

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Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

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The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

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Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers

21 January 2018

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Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin

21 January 2018

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Gemfibrozil greatly increases plasma concentrations of cerivastatin

21 January 2018

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Cerivastatin and reports of fatal rhabdomyolysis

21 January 2018

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Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

21 January 2018

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Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

1 reference

Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients

21 January 2018

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Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression

21 January 2018

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Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis.

21 January 2018

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Rhabdomyolysis after concomitant use of cyclosporine and simvastatin in a patient transplanted for multiple myeloma

21 January 2018

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Rhabdomyolysis triggered by cytomegalovirus infection in a heart transplant patient on concomitant cyclosporine and atorvastatin therapy

21 January 2018

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Statin-induced rhabdomyolysis

21 January 2018

1 reference

Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein.

21 January 2018

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Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2.

21 January 2018

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Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

21 January 2018

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Enterohepatic disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine and gemfibrozil.

21 January 2018

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Quinidine reduces biliary clearance of digoxin in man.

21 January 2018

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Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.

21 January 2018

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Interaction of common azole antifungals with P glycoprotein

21 January 2018

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Role of P-glycoprotein in pharmacokinetics and drug interactions of digoxin and beta-methyldigoxin in rats

21 January 2018

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Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay

21 January 2018

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Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.

21 January 2018

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A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

21 January 2018

1 reference

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

21 January 2018

1 reference

Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin

21 January 2018

1 reference

Pharmacogenetics of drug-induced liver injury

21 January 2018

1 reference

Transporter-mediated drug uptake and efflux: important determinants of adverse drug reactions

21 January 2018

1 reference

In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy

21 January 2018

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The effect of probenecid on the renal tubular excretion of benzylpenicillin

21 January 2018

1 reference

Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney

21 January 2018

1 reference

Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices

21 January 2018

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Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.

21 January 2018

1 reference

Characterization of ochratoxin A transport by human organic anion transporters

21 January 2018

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Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

21 January 2018

1 reference

Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans

21 January 2018

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Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors

21 January 2018

1 reference

(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue

21 January 2018

1 reference

Antiviral drug-induced nephrotoxicity

21 January 2018

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Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).

21 January 2018

1 reference

Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients

21 January 2018

1 reference

Cidofovir for cytomegalovirus reactivation in pediatric patients after hematopoietic stem cell transplantation

21 January 2018

1 reference

Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients.

21 January 2018

1 reference

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

21 January 2018

1 reference

Metformin transport by renal basolateral organic cation transporter hOCT2.

21 January 2018

1 reference

Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection

21 January 2018

1 reference

Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3

21 January 2018

1 reference

Reduction of metformin renal tubular secretion by cimetidine in man

21 January 2018

1 reference

Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.

21 January 2018

1 reference

Weekly high-dose cisplatin is a feasible treatment option: analysis on prognostic factors for toxicity in 400 patients

21 January 2018

1 reference

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

21 January 2018

1 reference

Molecular mechanisms of resistance and toxicity associated with platinating agents

21 January 2018

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Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

21 January 2018

1 reference

Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2).

21 January 2018

1 reference

Interaction of Cisplatin with the human organic cation transporter 2.

21 January 2018

1 reference

Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions

21 January 2018

1 reference

Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase

21 January 2018

1 reference

Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity

21 January 2018

1 reference

Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity

21 January 2018

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Nephrotoxicity of platinum complexes is related to basolateral organic cation transport

21 January 2018

1 reference

Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2.

21 January 2018

1 reference

Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms

21 January 2018

1 reference

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

1 reference

Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.

21 January 2018

1 reference

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

21 January 2018

1 reference

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

21 January 2018

1 reference

Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

21 January 2018

1 reference

Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells

21 January 2018

1 reference

Effect of quinidine on plasma concentration and renal clearance of digoxin. A clinically important drug interaction

21 January 2018

1 reference

Pharmacokinetics of digoxin in patients subjected to the quinidine-digoxin interaction

21 January 2018

1 reference

Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers

21 January 2018

1 reference

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.

21 January 2018

1 reference

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo

21 January 2018

1 reference

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

21 January 2018

1 reference

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

21 January 2018

1 reference

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

21 January 2018

1 reference

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease

21 January 2018

1 reference

Effects of fluvoxamine on lansoprazole pharmacokinetics in relation to CYP2C19 genotypes

21 January 2018

1 reference

Cyclosporine markedly raises the plasma concentrations of repaglinide

21 January 2018

1 reference

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine

21 January 2018

1 reference

Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.

21 January 2018

1 reference

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis

21 January 2018

1 reference

Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol

21 January 2018

1 reference

Identification of influx transporter for the quinolone antibacterial agent levofloxacin

21 January 2018

1 reference

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

21 January 2018

1 reference

Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium.

21 January 2018

1 reference

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

21 January 2018

1 reference

Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin

21 January 2018

1 reference

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart

21 January 2018

1 reference

Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.

21 January 2018

1 reference

Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1.

21 January 2018

1 reference

The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost

21 January 2018

1 reference

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

21 January 2018

1 reference

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

21 January 2018

1 reference

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

21 January 2018

1 reference

Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans

21 January 2018

1 reference

Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide

21 January 2018

1 reference

Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel

21 January 2018

1 reference

Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

21 January 2018

1 reference

Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies

21 January 2018

1 reference

Interactions of human organic anion transporters with diuretics.

21 January 2018

1 reference

Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers

21 January 2018

1 reference

Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

21 January 2018

1 reference

Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor

21 January 2018

1 reference

Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).

21 January 2018

1 reference

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium

21 January 2018

1 reference

Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons

21 January 2018

1 reference

Interaction of beta-blockers with the renal uptake transporter OCT2.

21 January 2018

1 reference

Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).

21 January 2018

1 reference

Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a nov

21 January 2018

1 reference

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice

21 January 2018

1 reference

Polarized transport of docetaxel and vinblastine mediated by P-glycoprotein in human intestinal epithelial cell monolayers

21 January 2018

1 reference

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

21 January 2018

1 reference

Reduced cyclosporin accumulation in multidrug-resistant cells.

21 January 2018

1 reference

P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels.

21 January 2018

1 reference

HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833.

21 January 2018

1 reference

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

21 January 2018

1 reference

Effect of cimetidine and ranitidine on pharmacokinetics and pharmacodynamics of a single dose of dofetilide

21 January 2018

1 reference

Itraconazole, a P-Glycoprotein and CYP3A4 Inhibitor, Markedly Raises the Plasma Concentrations and Enhances the Renin-Inhibiting Effect of Aliskiren

21 January 2018

1 reference

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

21 January 2018

1 reference

Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/BPB.21.1062

Identifiers

DOI

10.2217/PGS.11.44

1 reference

25 August 2017

1 reference

PubMed ID

21787191