(Q37915428)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

review article

1 reference

title

Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

10 February 2020

main subject

pathogenesis

0 references

endoplasmic reticulum

0 references

0 references

author

Adam Walker

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Julie D Atkin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

author name string

Julie D Atkin

series ordinal

2

1 reference

25 August 2017

language of work or name

1 reference

10 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

page(s)

754-763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834058%20AND%20SRC:MED&resulttype=core&format=json

Endoplasmic reticulum stress responses

10 February 2020

cites work

1 reference

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis

21 January 2018

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Prognostic factors in ALS: A critical review

21 January 2018

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Unraveling the mechanisms involved in motor neuron degeneration in ALS

21 January 2018

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Genetics of motor neuron disorders: new insights into pathogenic mechanisms

21 January 2018

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

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Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

21 January 2018

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TDP-43 A315T mutation in familial motor neuron disease

21 January 2018

1 reference

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

TDP-43 mutation in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

Exome sequencing reveals VCP mutations as a cause of familial ALS

21 January 2018

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Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

21 January 2018

1 reference

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

21 January 2018

1 reference

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

21 January 2018

1 reference

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

21 January 2018

1 reference

The unfolded protein response in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease

21 January 2018

1 reference

ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration

21 January 2018

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The epidemiology of motor neuron diseases: a review of recent studies

21 January 2018

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Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

21 January 2018

1 reference

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

21 January 2018

1 reference

Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

21 January 2018

1 reference

Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients

21 January 2018

1 reference

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis

21 January 2018

1 reference

Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation

21 January 2018

1 reference

Peripheral ER structure and function

21 January 2018

1 reference

A trip to the ER: coping with stress

21 January 2018

1 reference

Apoptosis induced by staurosporine alters chaperone and endoplasmic reticulum proteins: Identification by quantitative proteomics

21 January 2018

1 reference

Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum

21 January 2018

1 reference

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

1 reference

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

21 January 2018

1 reference

Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha

21 January 2018

1 reference

Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response

21 January 2018

1 reference

Intracellular signaling by the unfolded protein response

21 January 2018

1 reference

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

1 reference

Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins

21 January 2018

1 reference

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

21 January 2018

1 reference

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 January 2018

1 reference

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

21 January 2018

1 reference

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses

21 January 2018

1 reference

Gene-specific regulation by general translation factors

21 January 2018

1 reference

PERK and PKR: old kinases learn new tricks

21 January 2018

1 reference

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

1 reference

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

21 January 2018

1 reference

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

21 January 2018

1 reference

Regulation of apoptosis by endoplasmic reticulum pathways.

21 January 2018

1 reference

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells.

21 January 2018

1 reference

Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.

21 January 2018

1 reference

ER stress and UPR in familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

21 January 2018

1 reference

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

21 January 2018

1 reference

Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice.

21 January 2018

1 reference

Expression of an endoplasmic reticulum-resident chaperone, glucose-regulated stress protein 78, in the spinal cord of a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS.

21 January 2018

1 reference

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

21 January 2018

1 reference

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

1 reference

Proteins of the PDI family: unpredicted non-ER locations and functions

21 January 2018

1 reference

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

21 January 2018

1 reference

Reticulon-4A (Nogo-A) redistributes protein disulfide isomerase to protect mice from SOD1-dependent amyotrophic lateral sclerosis

21 January 2018

1 reference

Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosis

21 January 2018

1 reference

XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.

21 January 2018

1 reference

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice

21 January 2018

1 reference

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

1 reference

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells

21 January 2018

1 reference

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

21 January 2018

1 reference

Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis

21 January 2018

1 reference

The p.P56S mutation in the VAPB gene is not due to a single founder: the first European case

21 January 2018

1 reference

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

21 January 2018

1 reference

The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors

21 January 2018

1 reference

Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

21 January 2018

1 reference

VAPB interacts with and modulates the activity of ATF6.

21 January 2018

1 reference

AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway

21 January 2018

1 reference

hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction

21 January 2018

1 reference

A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism

21 January 2018

1 reference

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

21 January 2018

1 reference

Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord.

21 January 2018

1 reference

A Golgi fragmentation pathway in neurodegeneration

21 January 2018

1 reference

Glutamate neurotoxicity, oxidative stress and mitochondria.

21 January 2018

1 reference

Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders

21 January 2018

1 reference

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

21 January 2018

1 reference

Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons

21 January 2018

1 reference

TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage

21 January 2018

1 reference

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation

21 January 2018

1 reference

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

21 January 2018

1 reference

VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death

21 January 2018

1 reference

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

21 January 2018

1 reference

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload.

21 January 2018

1 reference

Amyotrophic lateral sclerosis in an urban setting

21 January 2018

1 reference

ALSOD: The Amyotrophic Lateral Sclerosis Online Database

21 January 2018

1 reference