(Q37919395)

25 August 2017

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title

Molecular oncology of lung cancer (English)

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25 August 2017

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2

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25 August 2017

7

Katsuyuki Kiura

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25 August 2017

Shinichi Toyooka

1

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25 August 2017

Junichi Soh

3

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25 August 2017

Keiju Aokage

4

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25 August 2017

Masaomi Yamane

5

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25 August 2017

Takahiro Oto

6

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25 August 2017

Shinichiro Miyoshi

8

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25 August 2017

publication date

18 August 2011

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General thoracic and cardiovascular surgery

25 August 2017

published in

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25 August 2017

volume

59

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25 August 2017

issue

8

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25 August 2017

page(s)

527-537

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https://scigraph.springernature.com/pub.10.1007/s11748-010-0743-3

25 August 2017

exact match

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cites work

Cancer statistics, 2009

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Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Oncogenic PI3K deregulates transcription and translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

PIK3CA mutations and copy number gains in human lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The role of targeting mammalian target of rapamycin in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The potential role of mTOR inhibitors in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Transcriptional regulation by MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

EGFR mutation is specific for terminal respiratory unit type adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Characterizing the cancer genome in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Recurrent gene fusions in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Anaplastic lymphoma kinase proteins in growth control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The cell cycle and the retinoblastoma protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Molecular genetics of small cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

p53: a frequent target for genetic abnormalities in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Mdm2 overexpression and p14(ARF) inactivation are two mutually exclusive events in primary human lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The FHIT gene 3p14.2 is abnormal in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Vascular endothelial growth factor is a secreted angiogenic mitogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

A genetic model for colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

DNA methylation in small lung adenocarcinoma with bronchioloalveolar carcinoma components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Alterations of the Notch pathway in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Exploiting the balance between life and death: targeted cancer therapy and "oncogenic shock".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

MicroRNA classifiers for predicting prognosis of squamous cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

Mutational and Epigenetic Evidence for Independent Pathways for Lung Adenocarcinomas Arising in Smokers and Never Smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11748-010-0743-3

The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer

21 January 2018

1 reference

12 December 2020

Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering.

1 reference

12 December 2020

Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin

1 reference

12 December 2020

A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity

1 reference

12 December 2020

Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer

1 reference

12 December 2020

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients

1 reference

12 December 2020

Telomerase activity in small-cell and non-small-cell lung cancers

1 reference

12 December 2020

Relationship between matrix metalloproteinase 2 and lung cancer progression

1 reference

12 December 2020

Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines

1 reference

12 December 2020

5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer

1 reference

12 December 2020

Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer

1 reference

12 December 2020

Precursors to pulmonary neoplasia

1 reference

12 December 2020

DNA methylation profiles of lung tumors

1 reference

12 December 2020

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

1 reference

12 December 2020

Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma.

1 reference

12 December 2020

p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features

1 reference

12 December 2020

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

1 reference

12 December 2020

10.1007/S11748-010-0743-3

Identifiers

DOI

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25 August 2017

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