(Q37931062)

25 August 2017

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title

Analysis of amyloid precursor protein function in Drosophila melanogaster (English)

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25 August 2017

main subject

Drosophila melanogaster

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Doris Kretzschmar

3

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author name string

Burkhard Poeck

series ordinal

1

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25 August 2017

Roland Strauss

series ordinal

2

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25 August 2017

publication date

13 September 2011

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Experimental Brain Research

25 August 2017

published in

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25 August 2017

volume

217

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25 August 2017

issue

3-4

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25 August 2017

page(s)

413-421

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Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture

25 August 2017

cites work

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BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION

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21 January 2018

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A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function

21 January 2018

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

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What the evolution of the amyloid protein precursor supergene family tells us about its function

21 January 2018

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apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor

21 January 2018

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Novel research horizons for presenilins and γ-secretases in cell biology and disease

21 January 2018

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

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Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

21 January 2018

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aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

21 January 2018

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Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

21 January 2018

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

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Drosophila amyloid precursor protein-like is required for long-term memory.

21 January 2018

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Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

21 January 2018

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Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury

21 January 2018

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Assembly and maturation of the Drosophila larval neuromuscular junction

21 January 2018

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Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

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A reporter for amyloid precursor protein gamma-secretase activity in Drosophila

21 January 2018

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Expression and characterization of the Drosophila X11-like/Mint protein during neural development

21 January 2018

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Mushroom body memoir: from maps to models

21 January 2018

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Isolation and characterization of Drosophila presenilin homolog

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability

21 January 2018

1 reference

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Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

21 January 2018

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

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Drosophila olfactory memory: single genes to complex neural circuits

21 January 2018

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Dealing with energy demand: the AMP-activated protein kinase

21 January 2018

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Drosophila homolog of APP-BP1 (dAPP-BP1) interacts antagonistically with APPL during Drosophila development

21 January 2018

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Sequential use of mushroom body neuron subsets during drosophila odor memory processing

21 January 2018

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A hidden program in Drosophila peripheral neurogenesis revealed: fundamental principles underlying sensory organ diversity

21 January 2018

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

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Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Specific functions of Drosophila amyloid precursor-like protein in the development of nervous system and nonneural tissues.

21 January 2018

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α-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential

21 January 2018

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Invertebrate models of Alzheimer's disease

21 January 2018

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Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene

21 January 2018

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Sialylation enhances the secretion of neurotoxic amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Homo- and heterodimerization of APP family members promotes intercellular adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Classical conditioning and retention in normal and mutantDrosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00221-011-2860-3

Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

1 reference

12 December 2020

Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.

1 reference

12 December 2020

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

12 December 2020

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

1 reference

12 December 2020

APPL, the Drosophila member of the APP-family, exhibits differential trafficking and processing in CNS neurons.

1 reference

12 December 2020

Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase

1 reference

12 December 2020

The Drosophila transcript encoded by the beta-amyloid protein precursor-like gene is restricted to the nervous system.

1 reference

12 December 2020

Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor

1 reference

12 December 2020

aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling

1 reference

12 December 2020

The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

1 reference

12 December 2020

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase

1 reference

12 December 2020

10.1007/S00221-011-2860-3

Identifiers

DOI

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25 August 2017

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