(Q37936211)

25 August 2017

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title

Malignant pirates of the immune system (English)

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25 August 2017

Lixin Rui

1

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25 August 2017

Roland Schmitz

series ordinal

2

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25 August 2017

Michele Ceribelli

series ordinal

3

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25 August 2017

Louis M Staudt

series ordinal

4

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25 August 2017

language of work or name

English

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publication date

20 September 2011

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25 August 2017

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25 August 2017

volume

12

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25 August 2017

issue

10

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25 August 2017

page(s)

933-940

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https://scigraph.springernature.com/pub.10.1038/ni.2094

25 August 2017

exact match

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cites work

Clonal evolution of a follicular lymphoma: evidence for antigen selection

1 reference

12 December 2020

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

12 December 2020

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

1 reference

12 December 2020

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas

1 reference

12 December 2020

The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia

1 reference

12 December 2020

Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation

1 reference

12 December 2020

Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin

1 reference

12 December 2020

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

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12 December 2020

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

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12 December 2020

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

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12 December 2020

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

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12 December 2020

Oncogenically active MYD88 mutations in human lymphoma

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12 December 2020

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

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12 December 2020

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR.

1 reference

12 December 2020

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

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12 December 2020

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

1 reference

12 December 2020

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

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12 December 2020

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

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12 December 2020

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

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12 December 2020

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

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12 December 2020

BRAF mutations in hairy-cell leukemia

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12 December 2020

PTEN gene alterations in lymphoid neoplasms

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12 December 2020

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia

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12 December 2020

DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: aberrant CH gene rearrangements in follicle center-cell lymphoma

1 reference

12 December 2020

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

1 reference

12 December 2020

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.

1 reference

12 December 2020

A microRNA polycistron as a potential human oncogene

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12 December 2020

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

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12 December 2020

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

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12 December 2020

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

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12 December 2020

Frequent inactivation of A20 in B-cell lymphomas

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12 December 2020

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

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12 December 2020

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance

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12 December 2020

PI3 kinase signals BCR-dependent mature B cell survival

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12 December 2020

Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.

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12 December 2020

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

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12 December 2020

Cooperative epigenetic modulation by cancer amplicon genes

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12 December 2020

The human thymus contains a novel population of B lymphocytes

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12 December 2020

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

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12 December 2020

Multiple layers of B cell memory with different effector functions

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12 December 2020

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival

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12 December 2020

Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

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12 December 2020

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

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12 December 2020

Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domain

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12 December 2020

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.

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12 December 2020

The isotype of the BCR as a surrogate for the GCB and ABC molecular subtypes in diffuse large B-cell lymphoma.

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12 December 2020

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

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12 December 2020

A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells

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12 December 2020

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization

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12 December 2020

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin

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12 December 2020

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

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12 December 2020

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

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12 December 2020

The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.

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12 December 2020

Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

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12 December 2020

The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.

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12 December 2020

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

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12 December 2020

The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

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12 December 2020

Oncogenic activation of NF-kappaB.

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12 December 2020

IRF4 addiction in multiple myeloma

1 reference

12 December 2020

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

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12 December 2020

Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells

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12 December 2020

B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression

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12 December 2020

Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory.

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12 December 2020

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

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12 December 2020

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia

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12 December 2020

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

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12 December 2020

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

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12 December 2020

Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.

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12 December 2020

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

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12 December 2020

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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12 December 2020

Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression

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12 December 2020

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

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12 December 2020

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

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12 December 2020

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12 December 2020

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

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12 December 2020

Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma

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12 December 2020

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

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12 December 2020

A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In Vivo

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12 December 2020

Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

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12 December 2020

Molecular underpinning of B-cell anergy

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12 December 2020

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

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12 December 2020

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

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12 December 2020

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

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12 December 2020

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

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12 December 2020

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

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12 December 2020

Nuclear factor kappa B is required for the development of marginal zone B lymphocytes

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12 December 2020

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

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12 December 2020

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

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12 December 2020

Predominant autoantibody production by early human B cell precursors

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12 December 2020

IRF4: Immunity. Malignancy! Therapy?

1 reference

12 December 2020

Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells

1 reference

12 December 2020

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells

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12 December 2020

Principles of cancer therapy: oncogene and non-oncogene addiction

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12 December 2020

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

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12 December 2020

BCL-6 protein is expressed in germinal-center B cells

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12 December 2020

Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization

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12 December 2020

Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease.

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12 December 2020

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

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12 December 2020

Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma

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12 December 2020

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

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12 December 2020

Molecular diagnosis of Burkitt's lymphoma

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12 December 2020

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

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12 December 2020

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

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12 December 2020

Acetylation inactivates the transcriptional repressor BCL6.

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12 December 2020

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop

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12 December 2020

The signaling tool box for tyrosine-based costimulation of lymphocytes

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12 December 2020

Disruption of the Bcl6 gene results in an impaired germinal center formation

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12 December 2020

JAK signaling globally counteracts heterochromatic gene silencing

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12 December 2020

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

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12 December 2020

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

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12 December 2020

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

1 reference

12 December 2020

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response

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12 December 2020

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

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12 December 2020

A loss-of-function RNA interference screen for molecular targets in cancer

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12 December 2020

Identifiers

DOI

10.1038/NI.2094

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Dimensions Publication ID

25 August 2017

1049239089

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