(Q37938299)

25 August 2017

1 reference

title

Respiratory chain complex I, a main regulatory target of the cAMP/PKA pathway is defective in different human diseases (English)

1 reference

25 August 2017

Anna Signorile

5

0 references

Antonio Gnoni

Antonio Gnoni

10

0 references

Domenico De Rasmo

Domenico De Rasmo

2

0 references

Vittoria Petruzzella

Vittoria Petruzzella

7

0 references

Giuseppe Palmisano

Giuseppe Palmisano

9

0 references

Anna Maria Sardanelli

Anna Maria Sardanelli

12

0 references

Salvatore Scacco

Salvatore Scacco

6

0 references

Sergio Papa

Sergio Papa

1

0 references

Loris Micelli

11

Loris Micelli

1 reference

25 August 2017

4

Damiano Panelli

1 reference

PubMed ID

21945319

Zuzana Technikova-Dobrova

25 August 2017

3

Zuzana Technikova-Dobrova

1 reference

25 August 2017

Francesco Papa

8

1 reference

PubMed ID

21945319

25 August 2017

language of work or name

English

0 references

publication date

19 September 2011

1 reference

25 August 2017

1 reference

25 August 2017

586

1 reference

25 August 2017

5

1 reference

25 August 2017

568-577

1 reference

The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains

25 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Energy converting NADH:quinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

21 January 2018

ATP and brain function

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The nuclear encoded subunits of complex I from bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The architecture of respiratory complex I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial free radical generation, oxidative stress, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Generation of superoxide by the mitochondrial Complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Towards the molecular mechanism of respiratory complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Bovine complex I is a complex of 45 different subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Identification and characterization of a common set of complex I assembly intermediates in mitochondria from patients with complex I deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Pathological mutations of the human NDUFS4 gene of the 18-kDa (AQDQ) subunit of complex I affect the expression of the protein and the assembly and function of the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Molecular genetics of complex I-deficient Chinese hamster cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mutation in the NDUFS4 gene of complex I abolishes cAMP-dependent activation of the complex in a child with fatal neurological syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Analysis of the subunit composition of complex I from bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Phosphorylation pattern of the NDUFS4 subunit of complex I of the mammalian respiratory chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The phosphorylation of subunits of complex I from bovine heart mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Assembly factors of human mitochondrial complex I and their defects in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Assembly of the oxidative phosphorylation system in humans: what we have learned by studying its defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Regulation of mitochondrial oxidative phosphorylation through cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Generation of reactive oxygen species by mitochondrial complex I: implications in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Progress on the mitochondrial permeability transition pore: regulation by complex I and ubiquinone analogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Human complex I deficiency: clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

cAMP-dependent phosphorylation of the nuclear encoded 18-kDa (IP) subunit of respiratory complex I and activation of the complex in serum-starved mouse fibroblast cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The genetics and pathology of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mutations in human nuclear genes encoding for subunits of mitochondrial respiratory complex I: the NDUFS4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Clinical and molecular findings in children with complex I deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Pathogenetic mechanisms in hereditary dysfunctions of complex I of the respiratory chain in neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial respiratory dysfunction and mutations in mitochondrial DNA in PINK1 familial parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial DNA mutations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

A mitochondrial protein compendium elucidates complex I disease biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Occurrence of A-kinase anchor protein and associated cAMP-dependent protein kinase in the inner compartment of mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Cyclic nucleotide research -- still expanding after half a century

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

AKAP signalling complexes: focal points in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The biological functions of A-kinase anchor proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: enzyme and substrate characterization and functional role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Organelle-specific targeting of protein kinase AII (PKAII). Molecular and in situ characterization of murine A kinase anchor proteins that recruit regulatory subunits of PKAII to the cytoplasmic surface of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Serine (threonine) phosphatase(s) acting on cAMP-dependent phosphoproteins in mammalian mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

cAMP controls oxygen metabolism in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Transcriptional regulation by the phosphorylation-dependent factor CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Sensing of energy and nutrients by AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Cyclic AMP-responsive element binding protein in brain mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The protein import motor of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

cAMP-dependent protein kinase regulates the mitochondrial import of the nuclear encoded NDUFS4 subunit of complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mitochondrial DNA mutations and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Demonstration of a new pathogenic mutation in human complex I deficiency: a 5-bp duplication in the nuclear gene encoding the 18-kD (AQDQ) subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Mutations in the NDUFS4 gene of mitochondrial complex I alter stability of the splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

A nonsense mutation in the NDUFS4 gene encoding the 18 kDa (AQDQ) subunit of complex I abolishes assembly and activity of the complex in a patient with Leigh-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Molecular diagnostics of mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

The role of perforin and granzymes in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.09.019

10.1016/J.FEBSLET.2011.09.019

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

21945319